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Results for “Metastatic Urothelial Cancer”

466 trials

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Showing 20 of 466 results

Testing effectiveness (Phase 2)WithdrawnNCT05574504
What this trial is testing

Phase II Trial of Lurbinectedin Combined With Avelumab as Switch Maintenance Firstline Therapy

Who this might be right for
Metastatic CancerUrothelial Carcinoma
AdventHealth
Testing effectiveness (Phase 2)Active Not RecruitingNCT03093922
What this trial is testing

Two Dosing Schedules of Atezolizumab in Combination With Gemcitabine and Cisplatin as First-Line Treatment for Metastatic Bladder Cancer

Who this might be right for
Urothelial CarcinomaLocally AdvancedUnresectable
Memorial Sloan Kettering Cancer Center 32
Early research (Phase 1)Study completedNCT02437370
What this trial is testing

Pembrolizumab and Docetaxel or Gemcitabine Hydrochloride in Treating Patients Urothelial Cancer

Who this might be right for
Metastatic Urothelial Carcinoma of the Renal Pelvis and UreterRecurrent Bladder CarcinomaRecurrent Urothelial Carcinoma of the Renal Pelvis and Ureter+6 more
University of California, Davis 32
Large-scale testing (Phase 3)Study completedNCT03410693
What this trial is testing

Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Carcinoma, Transitional Cell
Bayer 175
Very early researchNot Yet RecruitingNCT07671092
What this trial is testing

Imaging Study in Metastatic UC, HR+ and HER2- Breast Cancer, TNBC, and NSCLC

Who this might be right for
Metastatic Urothelial CarcinomaBreast CancerTNBC - Triple-Negative Breast Cancer+2 more
RayzeBio, Inc. 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06483334
What this trial is testing

Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

Who this might be right for
Metastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Merck Sharp & Dohme LLC 38
Large-scale testing (Phase 3)Study completedNCT02256436
What this trial is testing

Pembrolizumab (MK-3475) Versus Paclitaxel, Docetaxel, or Vinflunine for Participants With Advanced Urothelial Cancer (MK-3475-045/KEYNOTE-045)

Who this might be right for
Urothelial Cancer
Merck Sharp & Dohme LLC 542
Not applicableUnknownNCT03230201
What this trial is testing

Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma)

Who this might be right for
RecurrenceMetastasisUpper Tract Urothelial Carcinoma+1 more
Peking University First Hospital 80
Testing effectiveness (Phase 2)UnknownNCT03676946
What this trial is testing

A Clinical Study of PD-L1 Antibody ZKAB001（Drug Code） in Locally Advanced and Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Lee's Pharmaceutical Limited 15
Early research (Phase 1)Ended earlyNCT02608125
What this trial is testing

A Dose Escalation Study in Solid Tumors and a Dose Expansion Study of PRN1371 in Adult Patients With Metastatic Urothelial Carcinoma

Who this might be right for
Solid TumorsMetastatic Urothelial Carcinoma & Renal Pelvis & Ureter
Principia Biopharma, a Sanofi Company 45
Testing effectiveness (Phase 2)Looking for participantsNCT05269381
What this trial is testing

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+98 more
Mayo Clinic 138
Testing effectiveness (Phase 2)Ended earlyNCT03029832
What this trial is testing

MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-Based Therapy

Who this might be right for
Urothelial Carcinoma
Genentech, Inc. 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Looking for participantsNCT07034053
What this trial is testing

Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Advanced Urothelial CarcinomaMetastatic Urothelial Cancer
Ekaterina Laukhtina 50
Testing effectiveness (Phase 2)Study completedNCT02178241
What this trial is testing

Gemcitabine Hydrochloride and Eribulin Mesylate in Treating Patients With Bladder Cancer That is Advanced or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Ureter CarcinomaMetastatic Urethral CarcinomaStage III Bladder Urothelial Carcinoma AJCC v6 and v7+7 more
National Cancer Institute (NCI) 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT05101096
What this trial is testing

Study of Sacituzumab Govitecan (SG) in Japanese Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Triple-Negative Breast CancerHR+/HER2- Metastatic Breast Cancer+1 more
Gilead Sciences 135
Testing effectiveness (Phase 2)Looking for participantsNCT05394337
What this trial is testing

Neoadjuvant PD-1 Plus TIGIT Blockade in Patients With Cisplatin-Ineligible Operable High-Risk Urothelial Carcinoma

Who this might be right for
Metastatic Malignancy
M.D. Anderson Cancer Center 10
Not applicableStudy completedNCT05902494
What this trial is testing

HER2 and LA/mUC: A Multi-country Chart Review Cohort Study

Who this might be right for
Urothelial Carcinoma
Seagen, a wholly owned subsidiary of Pfizer 389
Testing effectiveness (Phase 2)Study completedNCT05219435
What this trial is testing

Study of NIVOLUMAB/IPILIMUMAB Maintenance in Unresectable Locally Advanced or Metastatic Urothelial Cancer

Who this might be right for
Urothelial Cancer
Spanish Oncology Genito-Urinary Group 25
Early research (Phase 1)Temporarily pausedNCT05958199
What this trial is testing

NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7

Who this might be right for
Metastatic Malignant Neoplasm
NextPoint Therapeutics, Inc. 131
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