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Results for “Metastatic Urothelial Carcinoma”

455 trials

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Showing 20 of 455 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03854474
What this trial is testing

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaStage III Bladder Cancer AJCC v8+1 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Looking for participantsNCT04724018
What this trial is testing

Sacituzumab Govitecan Plus EV in Metastatic UC

Who this might be right for
Urothelial CancerMetastatic Urothelial CarcinomaMetastatic Urothelial Carcinoma of the Renal Pelvis and Ureter+1 more
Dana-Farber Cancer Institute 106
Testing effectiveness (Phase 2)WithdrawnNCT06018116
What this trial is testing

A Canadian Trial of Bicalutamide in Patients Receiving Maintenance Avelumab for Metastatic Urothelial Cancer.

Who this might be right for
Metastatic Urothelial Carcinoma
CHU de Quebec-Universite Laval
Early research (Phase 1)Study completedNCT01522820
What this trial is testing

Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligoastrocytomaAnaplastic Oligodendroglioma+62 more
Roswell Park Cancer Institute 18
Not applicableLooking for participantsNCT07390617
What this trial is testing

Neuropathy Caused by Enfortumab Vedotin in People With Urothelial Carcinoma

Who this might be right for
NeuropathyUrothelial CarcinomaMetastatic Urothelial Carcinoma
Memorial Sloan Kettering Cancer Center 50
Testing effectiveness (Phase 2)Study completedNCT02006667
What this trial is testing

Herceptin (Trastuzumab) Combination Therapy in Patients With Metastatic Urothelial Cancer

Who this might be right for
Urinary Tract Cancer
Hoffmann-La Roche 13
Large-scale testing (Phase 3)Looking for participantsNCT06738251
What this trial is testing

A Phase III Study of SHR-A2102 Versus Investigator-selected Therapy in Advanced Urothelial Carcinoma

Who this might be right for
Advanced Urothelial Carcinoma
Shanghai Hengrui Pharmaceutical Co., Ltd. 402
Testing effectiveness (Phase 2)Study completedNCT01090466
What this trial is testing

Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium

Who this might be right for
Bladder CancerTransitional Cell Cancer of the Renal Pelvis and UreterUrethral Cancer
Cardiff University 15
Early research (Phase 1)Study completedNCT01963052
What this trial is testing

ASG-15ME is a Study of Escalating Doses of AGS15E Given as Monotherapy in Subjects With Metastatic Urothelial Cancer

Who this might be right for
Metastatic Urothelial Cancer
Astellas Pharma Global Development, Inc. 93
Testing effectiveness (Phase 2)Active Not RecruitingNCT04152499
What this trial is testing

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Who this might be right for
Epithelial Ovarian CancerGastric AdenocarcinomaGastroesophageal Junction Adenocarcinoma+7 more
Klus Pharma Inc. 1,410
Testing effectiveness (Phase 2)Active Not RecruitingNCT05645692
What this trial is testing

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

Who this might be right for
Urothelial Cancer
Hoffmann-La Roche 204
Testing effectiveness (Phase 2)Active Not RecruitingNCT05845814
What this trial is testing

Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04)

Who this might be right for
Metastatic Urothelial CarcinomaUrothelial Neoplasms
Merck Sharp & Dohme LLC 390
Large-scale testing (Phase 3)Looking for participantsNCT06493552
What this trial is testing

Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors

Who this might be right for
Muscle-Invasive Bladder CarcinomaMetastatic Urothelial Carcinoma
Vasgene Therapeutics, Inc 700
Early research (Phase 1)Looking for participantsNCT06439836
What this trial is testing

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Who this might be right for
Metastatic Urothelial CarcinomaUnresectable Urothelial Carcinoma
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Study completedNCT03464734
What this trial is testing

Pembrolizumab and Nab Paclitaxel in Patients With Metastatic Urothelial Carcinoma

Who this might be right for
Metastatic Urothelial Carcinoma
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 70
Testing effectiveness (Phase 2)Looking for participantsNCT07043972
What this trial is testing

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Fox Chase Cancer Center 55
Early research (Phase 1)Not Yet RecruitingNCT07353294
What this trial is testing

Propranolol With Tislelizumab Plus GC in Neoadjuvant Bladder UC

Who this might be right for
Bladder Urothelial CarcinomaLymph Node Metastasis
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 12
Testing effectiveness (Phase 2)Ended earlyNCT04639245
What this trial is testing

Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Solid Neoplasm+3 more
Fred Hutchinson Cancer Center 1
Testing effectiveness (Phase 2)Study completedNCT00805129
What this trial is testing

Everolimus (RAD001) in Metastatic Transitional Cell Carcinoma of the Urothelium

Who this might be right for
Bladder CancerMetastatic Transitional Cell Carcinoma
Memorial Sloan Kettering Cancer Center 46
Testing effectiveness (Phase 2)UnknownNCT03544723
What this trial is testing

Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.

Who this might be right for
Solid TumorLymphoma
MultiVir, Inc. 40
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