Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Metastatic or Locally Advanced Cancer”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05784012
What this trial is testing

Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Grupo Español de Tratamiento de Tumores de Cabeza y Cuello 34
Early research (Phase 1)Study completedNCT00648102
What this trial is testing

Phase I Study of CDX-1307, hCG-B Vaccine, for Patients With Incurable, Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian Cancer

Who this might be right for
Breast CancerColorectal CancerPancreatic Cancer+2 more
Celldex Therapeutics 36
Testing effectiveness (Phase 2)Study completedNCT03833661
What this trial is testing

M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)

Who this might be right for
Biliary Tract CancerCholangiocarcinomaGallbladder Cancer
EMD Serono Research & Development Institute, Inc. 159
Testing effectiveness (Phase 2)Study completedNCT04432454
What this trial is testing

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Who this might be right for
Metastatic Breast Cancer
Sermonix Pharmaceuticals Inc. 29
Testing effectiveness (Phase 2)Looking for participantsNCT06985602
What this trial is testing

Adebrelimab With Chemoradiotherapy and Surgery for G/GEJ

Who this might be right for
Gastroesophageal AdenocarcinomaGastric Adenocarcinoma
Jiangsu Cancer Institute & Hospital 30
Testing effectiveness (Phase 2)Ended earlyNCT00006001
What this trial is testing

SU5416 in Treating Patients With Metastatic or Locally Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Study completedNCT01514526
What this trial is testing

Clinical Trial of Dovitinib in First-line Metastatic or Locally Advanced Non-resectable Adrenocortical Carcinoma

Who this might be right for
Adrenocortical Carcinoma
Spanish Oncology Genito-Urinary Group 17
Early research (Phase 1)Looking for participantsNCT06582017
What this trial is testing

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

Who this might be right for
Ovarian CancerPancreas CancerUrothelial Carcinoma+6 more
Nammi Therapeutics Inc 100
Testing effectiveness (Phase 2)Study completedNCT01580735
What this trial is testing

ARQ 197 Plus Erlotinib in Patient With Locally Advanced or Metastatic EGFR Mutation-positive Non-small-cell Lung Cancer

Who this might be right for
Non-small-cell Lung Cancer
Kyowa Kirin Co., Ltd. 40
Testing effectiveness (Phase 2)Ended earlyNCT03149549
What this trial is testing

PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors

Who this might be right for
Solid Tumor, AdultBreast CancerNon Small Cell Lung Cancer+2 more
CytomX Therapeutics 99
Not applicableStudy completedNCT02106858
What this trial is testing

Stivarga Regulatory Post-Marketing Surveillance Study in Korea

Who this might be right for
Colorectal Neoplasms
Bayer 316
Early research (Phase 1)Looking for participantsNCT06349408
What this trial is testing

IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Fortvita Biologics (USA)Inc. 250
Testing effectiveness (Phase 2)Study completedNCT05661578
What this trial is testing

Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

Who this might be right for
PD-L1-selected Solid Tumors
Hoffmann-La Roche 64
Early research (Phase 1)Looking for participantsNCT07705035
What this trial is testing

DBC-664 in Adult Patients With Solid Tumors

Who this might be right for
Malignant Germ Cell TumorLung AdenocarcinomaGastric/Esophageal/Gastroesophageal Junction (GEJ) Adenocarcinoma+3 more
Duboce Biopharmaceuticals, Inc. 210
Testing effectiveness (Phase 2)Ended earlyNCT00323063
What this trial is testing

Gemcitabine +/- Imatinib Mesylate, Patients w/Previously Treated Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Rutgers, The State University of New Jersey 49
Large-scale testing (Phase 3)Not Yet RecruitingNCT07633873
What this trial is testing

SYS6010 Combined With Enlonstobart Versus Immunotherapy+ Platinum-based Chemotherapy for Patients With PD-L1-Positive Locally Advanced or Metastatic NSCLC(SYNSTAR 04)

Who this might be right for
Non-Small Cell Lung Cancer
CSPC Megalith Biopharmaceutical Co.,Ltd. 500
Large-scale testing (Phase 3)Study completedNCT00032175
What this trial is testing

Gemcitabine With or Without Capecitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Cancer Research UK 508
Testing effectiveness (Phase 2)Looking for participantsNCT06616766
What this trial is testing

A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)Solid Tumor
Yuhan Corporation 201
Testing effectiveness (Phase 2)Study completedNCT01561456
What this trial is testing

Study of AXL1717 Compared to Docetaxel to Treat Squamous Cell Carcinoma or Adenocarcinoma of the Lung

Who this might be right for
Non-small-cell Lung CancerSquamous Cell CarcinomaAdenocarcinoma of the Lung
Axelar AB 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04117945
What this trial is testing

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E NegativeKRAS Gene Mutation NegativeLocally Advanced Unresectable Colorectal Adenocarcinoma+10 more
Academic and Community Cancer Research United 22
Next Page