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Results for “Metastatic or Locally Advanced Malignancies”

2,594 trials

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Showing 20 of 2,594 results

Large-scale testing (Phase 3)Ended earlyNCT04335006
What this trial is testing

Study Comparing Carelizumab Plus Nab-paclitaxel and Apatinib, Carelizumab Plus Nab-paclitaxel, and Nab-paclitaxel in Patients With Advanced Triple Negative Breast Cancer.

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Jiangsu HengRui Medicine Co., Ltd. 80
Testing effectiveness (Phase 2)Study completedNCT00337649
What this trial is testing

Epothilone D in Combination With Herceptin (Trastuzumab) in Patients With HER-2 Positive Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 27
Testing effectiveness (Phase 2)Study completedNCT00301899
What this trial is testing

Trastuzumab and Pertuzumab in Treating Patients With Unresectable Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Trastuzumab

Who this might be right for
Breast Cancer
National Institutes of Health Clinical Center (CC) 37
Large-scale testing (Phase 3)Study completedNCT03410693
What this trial is testing

Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma

Who this might be right for
Carcinoma, Transitional Cell
Bayer 175
Large-scale testing (Phase 3)UnknownNCT02409199
What this trial is testing

Apatinib Versus Docetaxol Patients With Advanced Gastric Cancer

Who this might be right for
Gastric Carcinoma
Shanghai Zhongshan Hospital 66
Early research (Phase 1)Looking for participantsNCT05857332
What this trial is testing

SG1906 for CLDN18.2-Positive Solid Tumors

Who this might be right for
Locally Advanced Unresectable or Metastatic Solid Tumors
Hangzhou Sumgen Biotech Co., Ltd. 60
Testing effectiveness (Phase 2)Study completedNCT00867009
What this trial is testing

Induction and Maintenance Treatment of Advanced or Metastatic Non Squamous Non-Small Cell Lung Cancer

Who this might be right for
Non-Small-Cell Lung Cancer
Eli Lilly and Company 113
Post-approval studies (Phase 4)Looking for participantsNCT05035147
What this trial is testing

Albumin-bound Paclitaxel Combined With Gemcitabine First-line Inoperable Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital 934
Early research (Phase 1)Ended earlyNCT01876251
What this trial is testing

A Study Evaluating The PF-03084014 In Combination With Docetaxel In Patients With Advanced Breast Cancer

Who this might be right for
Breast Cancer Metastatic
Pfizer 30
Testing effectiveness (Phase 2)Study completedNCT00526045
What this trial is testing

Phase I-II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 in Advanced Solid Malignancies, and Efficacy in HER2+ or ER+ Locally Advanced or Metastatic Breast Cancer Patients

Who this might be right for
Breast CancerHematologic Neoplasms
Novartis Pharmaceuticals 117
Testing effectiveness (Phase 2)Study completedNCT01309633
What this trial is testing

Study Evaluating Two Loading Regimens of Sunitinib or Bevacizumab Alternating With Cisplatin and Gemcitabine as Induction Therapy for Locally Advanced Nasopharyngeal Carcinoma (NPC)

Who this might be right for
Nasopharyngeal Carcinoma
National University Hospital, Singapore 80
Testing effectiveness (Phase 2)Study completedNCT02031458
What this trial is testing

Atezolizumab in Participants With Programmed Death - Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Hoffmann-La Roche 667
Testing effectiveness (Phase 2)Study completedNCT04602078
What this trial is testing

Study of Atezolizumab Combined With Split-dose Gemcitabine Plus Cisplatin in Urothelial Carcinoma

Who this might be right for
Locally Advanced or Metastatic Urothelial Carcinoma
Spanish Oncology Genito-Urinary Group 82
Testing effectiveness (Phase 2)Ended earlyNCT00323063
What this trial is testing

Gemcitabine +/- Imatinib Mesylate, Patients w/Previously Treated Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Rutgers, The State University of New Jersey 49
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07128693
What this trial is testing

A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital of Zhengzhou University 60
Not applicableLooking for participantsNCT06771193
What this trial is testing

Study on Disease Characteristics and Treatment in Locally Advanced or Recurrent / Metastatic Cervical Cancer in Italy

Who this might be right for
Cervical CancerLocally Advanced Cervical CancerRecurrent Cervical Cancer+1 more
MSD Italia S.r.l. 200
Early research (Phase 1)Study completedNCT04094506
What this trial is testing

Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors

Who this might be right for
Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies
Astellas Pharma Inc 9
Early research (Phase 1)Study completedNCT00034463
What this trial is testing

ALIMTA (Pemetrexed) in Patients With Locally Advanced or Metastatic Cancer

Who this might be right for
MetastasesCancer
Eli Lilly and Company
Testing effectiveness (Phase 2)UnknownNCT00066547
What this trial is testing

Monoclonal Antibody Therapy in Treating Women With Locally Advanced or Metastatic Breast Cancer Previously Treated With Combination Chemotherapy

Who this might be right for
Breast Cancer
Jonsson Comprehensive Cancer Center
Early research (Phase 1)Looking for participantsNCT06349408
What this trial is testing

IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced Solid Tumor
Innovent Biologics (Suzhou) Co. Ltd. 250
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