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Results for “Methotrexate Toxicity”

27 trials

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Showing 20 of 27 results

Not applicableStudy completedNCT04283955
What this trial is testing

A Retrospective Cohort Study: The Influence of MTHFR C677T and A1298C on the High-dose Methotrexate-Related Toxicities in Pediatric Patients With Non-Hodgkin Lymphoma

Who this might be right for
Pediatric NHL
Sun Yat-sen University 93
Testing effectiveness (Phase 2)WithdrawnNCT00397501
What this trial is testing

BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerCognitive/Functional Effects+2 more
OHSU Knight Cancer Institute
Not applicableStudy completedNCT02133599
What this trial is testing

Prediction of Excretion and Toxicity of High Dose Methotrexate in Children and Adolescents With ALL

Who this might be right for
ALL
Ann & Robert H Lurie Children's Hospital of Chicago 23
Testing effectiveness (Phase 2)Study completedNCT01987102
What this trial is testing

Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.

Who this might be right for
Osteosarcoma
Isofol Medical AB 18
Testing effectiveness (Phase 2)Temporarily pausedNCT04668768
What this trial is testing

HM-178: Assessing Methods for Improvement in Methotrexate Toxicity Management and Detection of Central Nervous System Involvement of Aggressive Lymphoma

Who this might be right for
Lymphoma
Fox Chase Cancer Center 3
Testing effectiveness (Phase 2)Study completedNCT00727831
What this trial is testing

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

Who this might be right for
Chemotherapeutic Agent ToxicityLymphomaMucositis+1 more
University College, London 4
Not applicableUnknownNCT02174354
What this trial is testing

Methotrexate Polyglutamates as a Marker of Clinical Response and Toxicity in the Treatment of Psoriasis

Who this might be right for
Psoriasis ChronicInjury of Liver
King's College London 350
Post-approval studies (Phase 4)Not Yet RecruitingNCT06724952
What this trial is testing

Effect of Silymarin in Rheumatoid Arthritis Patients Treated With Methotrexate

Who this might be right for
Rheumatoid Arthritis (RA)
Tanta University 44
Early research (Phase 1)Study completedNCT00001298
What this trial is testing

A Trial of Carboxypeptidase-G2 (CPDG2) and Thymidine for the Management of Patients With Methotrexate Toxicity and Renal Dysfunction

Who this might be right for
Kidney Diseases
National Cancer Institute (NCI) 10
Early research (Phase 1)Study completedNCT00634504
What this trial is testing

Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze

Who this might be right for
OsteosarcomaLeukemiaLymphoma
BTG International Inc. 20
Testing effectiveness (Phase 2)Study completedNCT00004567
What this trial is testing

Comparison of Treatments to Maintain Disease Remission in Patients With Wegener's Granulomatosis and Related Vasculitis Syndromes

Who this might be right for
VasculitisWegener's Granulomatosis
National Institute of Allergy and Infectious Diseases (NIAID) 75
Not applicableUnknownNCT04168619
What this trial is testing

MTX-related Liver Toxicity in Psoriasis Patients, Using Ultrasound-based Techniques as a Diagnostic Tool

Who this might be right for
PsoriasisLiver Fibrosis
The University of Hong Kong 50
Not applicableStudy completedNCT02076997
What this trial is testing

Individualized High Dose Methotrexate to Treat Cancer in Children Who Have a Significant Risk for Side Effects to Methotrexate

Who this might be right for
Cancer
Baylor College of Medicine 23
Not applicableUnknownNCT06123403
What this trial is testing

Evaluation of High Dose Methotrexate Toxicity

Who this might be right for
Methotrexate Toxicity
Sohag University 100
Not applicableStudy completedNCT00993135
What this trial is testing

Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia

Who this might be right for
LeukemiaRenal Toxicity
Vanderbilt University Medical Center 10
Not applicableUnknownNCT06217224
What this trial is testing

Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma

Who this might be right for
Mucositis Oral
Instituto Nacional de Cancer, Brazil 53
Not applicableStudy completedNCT01886651
What this trial is testing

The Influence of Thiopurine Methyltransferase Activity on Toxicity After High-dose Methotrexate in Childhood Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic Leukemia
Rigshospitalet, Denmark 411
Testing effectiveness (Phase 2)Study completedNCT01399372
What this trial is testing

Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Who this might be right for
Chemotherapeutic Agent ToxicityCognitive/Functional EffectsLymphoma+2 more
Radiation Therapy Oncology Group 91
Testing effectiveness (Phase 2)UnknownNCT04351308
What this trial is testing

Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma

Who this might be right for
OsteosarcomaSurvivalChemotherapy Effect+1 more
Peking University People's Hospital 60
Not applicableNot Yet RecruitingNCT07406230
What this trial is testing

Methotrexate Early Toxicity Monitoring

Who this might be right for
Primary Central Nervous System Lymphoma
Assistance Publique Hopitaux De Marseille 50
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