Not applicableEnded earlyNCT01955213What this trial is testingMethylnaltrexone for Opioid Induced ConstipationWho this might be right forConstipation Amsterdam UMC, location VUmc 7
Early research (Phase 1)Study completedNCT01367535What this trial is testingEffects of MNTX on CYP450 2D6 in Metabolizers of DextromethorphanWho this might be right forHealthy Adults Bausch Health Americas, Inc. 54
Testing effectiveness (Phase 2)Ended earlyNCT01117376What this trial is testingMethylnaltrexone vs Erythromycin for Facilitating Gastric Emptying Time in Critically Ill PatientsWho this might be right forGastroparesis Shiraz University of Medical Sciences 42
Post-approval studies (Phase 4)Study completedNCT02403830What this trial is testingEffect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With MorphineWho this might be right forCoronary Artery Disease University of Florida 30
Early research (Phase 1)Study completedNCT01596777What this trial is testingEffects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy SubjectsWho this might be right forIntestinal Obstruction University Medicine Greifswald 15
Large-scale testing (Phase 3)UnknownNCT02574819What this trial is testingStudy of Methylnaltrexone in Opioid-Induced Constipation PatientsWho this might be right forOpioid-induced Constipation Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 198
Early research (Phase 1)Study completedNCT01367522What this trial is testingPharmacokinetics, Safety, and Tolerability of Methylnaltrexone in Volunteers With Impaired Hepatic FunctionWho this might be right forLiver Dysfunction Bausch Health Americas, Inc. 24
Early research (Phase 1)Study completedNCT01366365What this trial is testingStudy of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone BromideWho this might be right forHealthy Adults Bausch Health Americas, Inc. 28
Large-scale testing (Phase 3)Study completedNCT00387309What this trial is testingStudy Evaluating IV Methylnaltrexone for the Treatment of Post Operative IleusWho this might be right forPost Operative Bowel Dysfunction Bausch Health Americas, Inc. 495
Early research (Phase 1)Study completedNCT01367496What this trial is testingPharmacokinetics and Bioavailability of Single Subcutaneous Doses of Methylnaltrexone Versus Intravenous DoseWho this might be right forHealthy Subjects Bausch Health Americas, Inc. 6
Large-scale testing (Phase 3)Study completedNCT01186770What this trial is testingOral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant PainWho this might be right forOpioid-Induced Constipation Bausch Health Americas, Inc. 804
Post-approval studies (Phase 4)WithdrawnNCT00858754What this trial is testingStudy Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer SubjectsWho this might be right forOpioid-Induced Constipation Bausch Health Americas, Inc.
Early research (Phase 1)Study completedNCT01366326What this trial is testingEvaluate the Pharmacokinetics (PK) of Methylnaltrexone (MNTX) in Healthy Adult SubjectsWho this might be right forHealthy Adult Subjects Bausch Health Americas, Inc. 20
Early research (Phase 1)Study completedNCT01367509What this trial is testingPharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal FunctionWho this might be right forRenal Impairment Bausch Health Americas, Inc. 32
Post-approval studies (Phase 4)Study completedNCT02942550What this trial is testingMethylnaltrexone as a Method to Improve Ticagrelor Uptake in Morphine Treated STEMI PatientsWho this might be right forSTEMIMorphineTicagrelor+1 more Karolinska University Hospital 82
Early research (Phase 1)Study completedNCT01596764What this trial is testingEffects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time.Who this might be right forIntestinal Obstruction University Medicine Greifswald 16
Large-scale testing (Phase 3)Study completedNCT00528970What this trial is testingA Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia RepairWho this might be right forIleus Bausch Health Americas, Inc. 374
Post-approval studies (Phase 4)Study completedNCT01012960What this trial is testingOpioids and Esophageal FunctionWho this might be right forPharyngeal DysfunctionEsophageal Dysfunction Region Örebro County 13
Large-scale testing (Phase 3)WithdrawnNCT04083651What this trial is testingMethylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic CancerWho this might be right forPancreatic Cancer Bausch Health Americas, Inc.
Large-scale testing (Phase 3)Study completedNCT00401362What this trial is testingA a Single Dose Efficacy Study in Inducing Laxation in Advance Illness PatientsWho this might be right forAdvanced Illness Patients With Opioid Induced Constipation Bausch Health Americas, Inc. 154