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Results for “Methylnaltrexone”

48 trials

Showing 20 of 48 results

Testing effectiveness (Phase 2)Study completedNCT01367587
What this trial is testing

Safety and Gastrointestinal Effects of Intravenous Methylnaltrexone

Who this might be right for
Healthy Volunteers
Bausch Health Americas, Inc. 12
Early research (Phase 1)Study completedNCT01367496
What this trial is testing

Pharmacokinetics and Bioavailability of Single Subcutaneous Doses of Methylnaltrexone Versus Intravenous Dose

Who this might be right for
Healthy Subjects
Bausch Health Americas, Inc. 6
Not applicableStudy completedNCT01368562
What this trial is testing

Compassionate Use Study of Methylnaltrexone

Who this might be right for
Opioid-induced Constipation
Bausch Health Americas, Inc. 26
Early research (Phase 1)Study completedNCT01367509
What this trial is testing

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Who this might be right for
Renal Impairment
Bausch Health Americas, Inc. 32
Testing effectiveness (Phase 2)Study completedNCT01004393
What this trial is testing

Methylnaltrexone for Opioid-induced Constipation in Cancer Patients

Who this might be right for
NeoplasmsConstipationOpioid-Related Disorders
University of Vermont 12
Large-scale testing (Phase 3)Study completedNCT01186770
What this trial is testing

Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain

Who this might be right for
Opioid-Induced Constipation
Bausch Health Americas, Inc. 804
Post-approval studies (Phase 4)WithdrawnNCT00949377
What this trial is testing

Can Methylnaltrexone Safely Treat Opioid Related Constipation in the Emergency Department?

Who this might be right for
Colonic Inertia
Beth Israel Medical Center
Large-scale testing (Phase 3)WithdrawnNCT04151719
What this trial is testing

An Extension Study of Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Bausch Health Americas, Inc.
Post-approval studies (Phase 4)Study completedNCT00672139
What this trial is testing

Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness

Who this might be right for
Opioid-Induced Constipation
Bausch Health Americas, Inc. 156
Large-scale testing (Phase 3)UnknownNCT01050595
What this trial is testing

Methylnaltrexone for Treatment of Opiate-Induced Constipation in the Intensive Care Unit

Who this might be right for
Opioid-induced Constipation
St. John Health System, Michigan 80
Large-scale testing (Phase 3)WithdrawnNCT01360372
What this trial is testing

Effect of Methylnaltrexone (Relistor) on Digestion and Tolerance to Tube Feeding in Patients Treated With Opiates

Who this might be right for
Tube Feeding
Drexel University
Large-scale testing (Phase 3)WithdrawnNCT04083651
What this trial is testing

Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Bausch Health Americas, Inc.
Large-scale testing (Phase 3)Study completedNCT00401362
What this trial is testing

A a Single Dose Efficacy Study in Inducing Laxation in Advance Illness Patients

Who this might be right for
Advanced Illness Patients With Opioid Induced Constipation
Bausch Health Americas, Inc. 154
Post-approval studies (Phase 4)WithdrawnNCT00858754
What this trial is testing

Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects

Who this might be right for
Opioid-Induced Constipation
Bausch Health Americas, Inc.
Early research (Phase 1)Study completedNCT01367522
What this trial is testing

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone in Volunteers With Impaired Hepatic Function

Who this might be right for
Liver Dysfunction
Bausch Health Americas, Inc. 24
Early research (Phase 1)Study completedNCT01366326
What this trial is testing

Evaluate the Pharmacokinetics (PK) of Methylnaltrexone (MNTX) in Healthy Adult Subjects

Who this might be right for
Healthy Adult Subjects
Bausch Health Americas, Inc. 20
Post-approval studies (Phase 4)UnknownNCT03283020
What this trial is testing

Opioid-Induced Swallowing Dysfunction - The Impact of Bolus Volume

Who this might be right for
Pharyngeal DysfunctionPharyngeal Swallowing
Region Örebro County 20
Early research (Phase 1)Study completedNCT01367561
What this trial is testing

Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function

Who this might be right for
Healthy Males
Bausch Health Americas, Inc. 15
Post-approval studies (Phase 4)Study completedNCT01055704
What this trial is testing

Effect of Methylnaltrexone on GI Transit in Healthy Volunteers

Who this might be right for
Gastric Motility Disorder
Mayo Clinic 48
Large-scale testing (Phase 3)UnknownNCT02574819
What this trial is testing

Study of Methylnaltrexone in Opioid-Induced Constipation Patients

Who this might be right for
Opioid-induced Constipation
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 198
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