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Results for “Methylnaltrexone”

48 trials

Showing 20 of 48 results

Early research (Phase 1)Study completedNCT01367496
What this trial is testing

Pharmacokinetics and Bioavailability of Single Subcutaneous Doses of Methylnaltrexone Versus Intravenous Dose

Who this might be right for
Healthy Subjects
Bausch Health Americas, Inc. 6
Post-approval studies (Phase 4)WithdrawnNCT00858754
What this trial is testing

Study Evaluating Safety & Efficacy of Subcutaneous Methylnaltrexone on Opioid-Induced Constipation in Cancer Subjects

Who this might be right for
Opioid-Induced Constipation
Bausch Health Americas, Inc.
Post-approval studies (Phase 4)Study completedNCT00672477
What this trial is testing

Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness

Who this might be right for
Opioid-Induced Constipation
Bausch Health Americas, Inc. 237
Post-approval studies (Phase 4)Study completedNCT02403830
What this trial is testing

Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine

Who this might be right for
Coronary Artery Disease
University of Florida 30
Early research (Phase 1)Study completedNCT01367561
What this trial is testing

Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function

Who this might be right for
Healthy Males
Bausch Health Americas, Inc. 15
Post-approval studies (Phase 4)Study completedNCT01012960
What this trial is testing

Opioids and Esophageal Function

Who this might be right for
Pharyngeal DysfunctionEsophageal Dysfunction
Region Örebro County 13
Not applicableEnded earlyNCT01955213
What this trial is testing

Methylnaltrexone for Opioid Induced Constipation

Who this might be right for
Constipation
Amsterdam UMC, location VUmc 7
Large-scale testing (Phase 3)Study completedNCT00936884
What this trial is testing

Study Evaluating the Efficacy and Safety of Subcutaneous Methylnaltrexone (MOA-728) for the Treatment of Opioid-Induced-Constipation

Who this might be right for
Constipation
Bausch Health Americas, Inc. 50
Early research (Phase 1)Study completedNCT01366339
What this trial is testing

Tolerance and Pharmacokinetics Study of MNTX Tablets

Who this might be right for
Normal Healthy Volunteers
Bausch Health Americas, Inc. 37
Early research (Phase 1)Study completedNCT01367509
What this trial is testing

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Who this might be right for
Renal Impairment
Bausch Health Americas, Inc. 32
Testing effectiveness (Phase 2)Study completedNCT00640146
What this trial is testing

Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures

Who this might be right for
Opioid-induced Constipation
Bausch Health Americas, Inc. 37
Large-scale testing (Phase 3)Study completedNCT00528970
What this trial is testing

A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair

Who this might be right for
Ileus
Bausch Health Americas, Inc. 374
Early research (Phase 1)Study completedNCT01367535
What this trial is testing

Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan

Who this might be right for
Healthy Adults
Bausch Health Americas, Inc. 54
Post-approval studies (Phase 4)Study completedNCT02942550
What this trial is testing

Methylnaltrexone as a Method to Improve Ticagrelor Uptake in Morphine Treated STEMI Patients

Who this might be right for
STEMIMorphineTicagrelor+1 more
Karolinska University Hospital 82
Post-approval studies (Phase 4)UnknownNCT03283020
What this trial is testing

Opioid-Induced Swallowing Dysfunction - The Impact of Bolus Volume

Who this might be right for
Pharyngeal DysfunctionPharyngeal Swallowing
Region Örebro County 20
Early research (Phase 1)Study completedNCT01366365
What this trial is testing

Study of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone Bromide

Who this might be right for
Healthy Adults
Bausch Health Americas, Inc. 28
Post-approval studies (Phase 4)Study completedNCT00672139
What this trial is testing

Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness

Who this might be right for
Opioid-Induced Constipation
Bausch Health Americas, Inc. 156
Early research (Phase 1)Study completedNCT01015222
What this trial is testing

Dasatinib, Bevacizumab, Paclitaxel in Patients With Advanced Malignancies

Who this might be right for
Advanced Cancer
M.D. Anderson Cancer Center 122
Testing effectiveness (Phase 2)Study completedNCT03852524
What this trial is testing

Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention

Who this might be right for
Postoperative Ileus
Ohio State University 82
Testing effectiveness (Phase 2)Study completedNCT01367574
What this trial is testing

Methylnaltrexone in Patients With Opioid-Induced Bowel Dysfunction

Who this might be right for
Bowel Dysfunction
Bausch Health Americas, Inc. 39
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