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Results for “Microangiopathy”

66 trials

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Showing 20 of 66 results

Large-scale testing (Phase 3)Active Not RecruitingNCT04889430
What this trial is testing

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 34
Testing effectiveness (Phase 2)Ended earlyNCT02763644
What this trial is testing

Efficacy and Safety of LFG316 in Transplant Associated Microangiopathy (TAM) Patients

Who this might be right for
Transplant Associated Microangiopathy TAM
Novartis Pharmaceuticals 7
Not applicableStudy completedNCT02134171
What this trial is testing

Early Predictive Factors of Cardiac and Cerebral Involvement in TMA

Who this might be right for
Thrombotic MicroangiopathiesThrombotic Thrombocytopenic Purpura
Assistance Publique - Hôpitaux de Paris 119
Not applicableStudy completedNCT05449782
What this trial is testing

Macro- and Microvascular Response to Cocoa Flavanols in Healthy and Type 2 Diabetes

Who this might be right for
Microangiopathy, DiabeticPolyphenolOptical Tomography+3 more
University of Surrey 22
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 125
Not applicableStudy completedNCT02610036
What this trial is testing

Obliterating Diabetic Microangiopathy of the Diabetic Foot

Who this might be right for
Diabetic Foot
IRCCS Multimedica 60
Not applicableNot Yet RecruitingNCT07347990
What this trial is testing

Safety and Efficacy of Iptacopan in Patients With High-Risk Transplantation-Associated Thrombotic Microangiopathy

Who this might be right for
Thrombotic MicroangiopathyHematopoietic Stem Cell Transplantation (HSCT)
First Affiliated Hospital of Zhejiang University 30
Not applicableLooking for participantsNCT06759961
What this trial is testing

Post-transplant Thrombotic Microangiopathy: Evaluation of Outcomes at the Bologna Kidney Transplant Centre

Who this might be right for
MicroangiopathyKidney Transplant
IRCCS Azienda Ospedaliero-Universitaria di Bologna 250
Not applicableLooking for participantsNCT06376786
What this trial is testing

Italian iTTP Registry

Who this might be right for
TTP - Thrombotic Thrombocytopenic Purpura
Fondazione Luigi Villa 132
Large-scale testing (Phase 3)Ended earlyNCT04743804
What this trial is testing

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

Who this might be right for
Thrombotic Microangiopathy
Alexion Pharmaceuticals, Inc. 16
Not applicableLooking for participantsNCT04838249
What this trial is testing

Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System

Who this might be right for
TranssexualismTransgenderismAdiposity+3 more
University of Leipzig 80
Very early researchNot Yet RecruitingNCT07198815
What this trial is testing

A Preliminary Exploratory Clinical Trial to Evaluate the Efficacy of NPDR-01 Eye Drops in the Treatment of Non-Proliferative Diabetic Retinopathy

Who this might be right for
Non-proliferative Diabetic Retinopathy (NPDR)Diabetic Retinal MicroangiopathyRetinal Microaneurysms+1 more
Sichuan Academy of Medical Sciences 10
Not applicableLooking for participantsNCT07205861
What this trial is testing

Retrospective Epidemiological Study of Patients in the National Cohort of the French TMA Center

Who this might be right for
Thrombotic Thrombocytopenic Purpura (TTP)Immune Thrombotic Thrombocytopenic PurpuraThrombotic Microangiopathies+5 more
Assistance Publique - Hôpitaux de Paris 1,200
Large-scale testing (Phase 3)Looking for participantsNCT05935215
What this trial is testing

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 50
Not applicableUnknownNCT02220257
What this trial is testing

The Influence of Partial Remission Phase of Type 1 Diabetes on Patient Outcome

Who this might be right for
Diabetes Mellitus Type 1Remission of Type 1 DiabetesChronic Complications of Diabetes
Poznan University of Medical Sciences 140
Not applicableUnknownNCT06098378
What this trial is testing

Study of Patients With Thrombotic Microangiopathy Associated With Mitomycin C, Treated or Not With Eculizumab

Who this might be right for
Thrombotic Microangiopathies
University Hospital, Strasbourg, France 30
Large-scale testing (Phase 3)Study completedNCT04557735
What this trial is testing

Study of Ravulizumab in Pediatric Participants With HSCT-TMA

Who this might be right for
Thrombotic Microangiopathy
Alexion Pharmaceuticals, Inc. 41
Not applicableNot Yet RecruitingNCT06727955
What this trial is testing

Prospective Cohort Study on Predicting the Progression of Diabetic Microangiopathy Using Multimodal Eye Imaging

Who this might be right for
Diabetic Retinopathy
Peking University Third Hospital 250
Testing effectiveness (Phase 2)WithdrawnNCT03303313
What this trial is testing

An Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Alnylam Pharmaceuticals
Not applicableLooking for participantsNCT04777435
What this trial is testing

Therapeutic Orientation Test in Thrombotic Microangiopathy

Who this might be right for
Thrombotic Micro-angiopathy
University Hospital, Montpellier 100
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