Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Microsatellite High Cancers”

114 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 114 results

Not applicableNot Yet RecruitingNCT07645742
What this trial is testing

Pilot Study of Intermittent Fasting With Immune Checkpoint Inhibitors

Who this might be right for
Cancer (Advanced Stage)
West Virginia University 90
Testing effectiveness (Phase 2)Looking for participantsNCT03667170
What this trial is testing

KN035 for dMMR/MSI-H Advanced Solid Tumors

Who this might be right for
Solid Tumor
3D Medicines (Sichuan) Co., Ltd. 200
Testing effectiveness (Phase 2)UnknownNCT04411524
What this trial is testing

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Fudan University 50
Testing effectiveness (Phase 2)WithdrawnNCT04001101
What this trial is testing

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Who this might be right for
Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer
University of Colorado, Denver
Testing effectiveness (Phase 2)UnknownNCT04118933
What this trial is testing

PD-1 Antibody JS001 in MSI-H Advanced or Recurrent Colorectal Cancer

Who this might be right for
Colorectal Cancer
Xu jianmin 40
Testing effectiveness (Phase 2)Looking for participantsNCT04114136
What this trial is testing

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Who this might be right for
MelanomaNSCLCHepatocellular Carcinoma+5 more
Dan Zandberg 72
Early research (Phase 1)Ended earlyNCT05909995
What this trial is testing

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

Who this might be right for
MelanomaHepatocellular Carcinoma (HCC)Renal Cell Carcinoma (RCC)+3 more
Incyte Corporation 8
Testing effectiveness (Phase 2)Looking for participantsNCT06002789
What this trial is testing

Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC

Who this might be right for
Multiple CancerColorectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 17
Large-scale testing (Phase 3)Active Not RecruitingNCT05890742
What this trial is testing

A Clinical Trial Evaluating the Efficacy and Safety of IBI310 in Combination With Sintilimab, for Neoadjuvant Treatment of MSI-H/dMMR Resectable Colon Cancer

Who this might be right for
MSI-H
Innovent Biologics (Suzhou) Co. Ltd. 453
Large-scale testing (Phase 3)Active Not RecruitingNCT02997228
What this trial is testing

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Who this might be right for
Metastatic Colorectal AdenocarcinomaStage IV Colorectal Cancer AJCC v7
National Cancer Institute (NCI) 120
Large-scale testing (Phase 3)Looking for participantsNCT06686576
What this trial is testing

Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer

Who this might be right for
Colon Cancer
Qilu Pharmaceutical Co., Ltd. 363
Not applicableStudy completedNCT05162248
What this trial is testing

Microsatellite Instability in Colorectal Cancers

Who this might be right for
Colorectal CancerColorectal CarcinomaMicrosatellite Instability High+2 more
Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 231
Testing effectiveness (Phase 2)Temporarily pausedNCT05337735
What this trial is testing

A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

Who this might be right for
Microsatellite High CancersPeritoneal MesotheliomaExtrapulmonary High Grade+5 more
M.D. Anderson Cancer Center 140
Post-approval studies (Phase 4)Not Yet RecruitingNCT06897527
What this trial is testing

Evaluate the Safety of Dostarlimab in Adult Participants in India With Recurrent or Advanced Endometrial Cancer (EC)

Who this might be right for
Neoplasms, Endometrial
GlaxoSmithKline 100
Early research (Phase 1)Ended earlyNCT03866239
What this trial is testing

A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal Adenocarcinoma

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT04895722
What this trial is testing

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008)

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 302
Early research (Phase 1)Ended earlyNCT04187872
What this trial is testing

LITT and Pembrolizumab in Recurrent Brain Metastasis

Who this might be right for
MelanomaNon-small Cell Lung Carcinoma (NSCLC)Renal Cell Carcinoma (RCC)+12 more
University of Florida 10
Testing effectiveness (Phase 2)Looking for participantsNCT02332668
What this trial is testing

Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Who this might be right for
MelanomaLymphomaSolid Tumor+2 more
Merck Sharp & Dohme LLC 370
Testing effectiveness (Phase 2)WithdrawnNCT06331598
What this trial is testing

Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors with Resectable Disease with Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)

Who this might be right for
Solid Tumors
Hoffmann-La Roche
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07259473
What this trial is testing

Factors Influencing Immunotherapy Response in dMMR/MSI-H Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMismatch Repair Deficient or MSI-High Solid TumorsImmunotherapy
Shanghai Zhongshan Hospital 15
Load More Results