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Results for “Microsatellite Instability-High”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07731607
What this trial is testing

Sintilimab Monotherapy in Patients With Stage I-II MSI-H/dMMR Endometrial Cancer

Who this might be right for
MMRd Endometrial Cancer of Stage I~II
Wang Jianliu 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT05879822
What this trial is testing

Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Who this might be right for
Advanced Solid Tumor
Incyte Corporation 73
Testing effectiveness (Phase 2)Looking for participantsNCT07244705
What this trial is testing

ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC

Who this might be right for
Colorectal Cancer (Diagnosis)Colorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc. 66
Testing effectiveness (Phase 2)Active Not RecruitingNCT04817826
What this trial is testing

TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC.

Who this might be right for
Gastric CancerMicrosatellite Instability
Gruppo Oncologico del Nord-Ovest 31
Testing effectiveness (Phase 2)Looking for participantsNCT03736889
What this trial is testing

Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors

Who this might be right for
MSI-H/dMMR Solid Tumors
BeiGene 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07127822
What this trial is testing

Assessing Iparomlimab and Tuvonralimab in Recurrent or Metastatic MSI-H/dMMR Gastric Cancer

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMSI-H Cancer
Peking University 106
Not applicableLooking for participantsNCT07352280
What this trial is testing

Neoadjuvant Therapy With Tislelizumab for dMMR/MSI-H Stage II-III Colorectal Cancer

Who this might be right for
Colo-rectal Cancer (dMMR/MSI-H CRC)
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 30
Not applicableUnknownNCT06004713
What this trial is testing

Registry Study in MSI/dMMR Solid Tumors

Who this might be right for
DMMR CancerMSI-HSolid Tumor
Peking University Cancer Hospital & Institute 190
Testing effectiveness (Phase 2)Looking for participantsNCT07108270
What this trial is testing

Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC)

Who this might be right for
Neoplasms, Endometrial
GlaxoSmithKline 30
Testing effectiveness (Phase 2)Study completedNCT05535569
What this trial is testing

Phase Ib/II Study to Evaluate the Safety and Efficacy of Nivolumab in Combination With Paclitaxel in Epstein-Barr Virus(EBV)-Related, or Microsatellite Instability-High (MSI-H), or Programmed Cell Death Ligand 1 (PD-L1) Positive Advanced Gastric Cancer

Who this might be right for
Recurrent/Metastatic Gastric Cancer
Yonsei University 50
Testing effectiveness (Phase 2)Looking for participantsNCT06580574
What this trial is testing

Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers

Who this might be right for
Gastric CancerColon CancerMSI-H+1 more
Peking University 34
Testing effectiveness (Phase 2)Active Not RecruitingNCT03983993
What this trial is testing

Niraparib and Panitumumab in Patients With Advanced or Metastatic Colorectal Cancer

Who this might be right for
Advanced Microsatellite Stable Colorectal CarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaMicrosatellite Stable+3 more
Emory University 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT05217446
What this trial is testing

Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Pfizer 108
Large-scale testing (Phase 3)Not Yet RecruitingNCT07740720
What this trial is testing

The Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer

Who this might be right for
Neoplasms, Rectal
GlaxoSmithKline 90
Testing effectiveness (Phase 2)UnknownNCT03941574
What this trial is testing

A Clinical Study to Evaluate HLX10 Monotherapy for the Treatment of MSI-H or dMMR Solid Tumors That Failed to Respond to Standard Therapy

Who this might be right for
MSI-H Solid Malignant Tumor
Shanghai Henlius Biotech 108
Testing effectiveness (Phase 2)Study completedNCT03126110
What this trial is testing

Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies

Who this might be right for
Advanced MalignanciesMetastatic Cancer
Incyte Biosciences International Sàrl 145
Testing effectiveness (Phase 2)Active Not RecruitingNCT05200559
What this trial is testing

T-regulatory Cell Depletion With E7777 Combined With Pembrolizumab in Recurrent or Metastatic Solid Tumors

Who this might be right for
Epithelial Ovarian Cancer
Alexander B Olawaiye, MD 25
Not applicableStudy completedNCT07194954
What this trial is testing

Dietary Fiber and Probiotics in Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)Malnutrition (Calorie)
The First Hospital of Hebei Medical University 80
Testing effectiveness (Phase 2)Looking for participantsNCT07003022
What this trial is testing

Phase Ⅱ Clinical Trial of Cadonilimab Combined With Anti-angiogenic Agents in Metastatic dMMR/MSI-H CRC

Who this might be right for
Colo-rectal CancerMSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Fudan University 40
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