Not applicableStudy completedNCT07597330What this trial is testingPOD Risk for Colorectal Cancer SurgeryWho this might be right forColorectal Cancer (MSI-H)Postoperative Delirium (POD) LanZhou University 590
Not applicableNot Yet RecruitingNCT07656740What this trial is testingNon-Operative Management and Following Immunotherapy for Colorectal Cancer and Other GI CancersWho this might be right forGastrointestinal CancerColorectal (Colon or Rectal) CancerStomach (Gastric) Cancer Peking University Cancer Hospital & Institute 50
Not applicableStudy completedNCT04482608What this trial is testingThe mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and SurvivalWho this might be right forColorectal Cancer MetastaticMismatch Repair DeficiencyMicrosatellite Instability High Sun Yat-sen University 671
Testing effectiveness (Phase 2)UnknownNCT04636008What this trial is testingSintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal CancerWho this might be right forAnti-PD-1 AntibodyRadiotherapyRectal Cancer+2 more West China Hospital 20
Large-scale testing (Phase 3)Active Not RecruitingNCT05652894What this trial is testingHX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal CancerWho this might be right forMetastatic Colorectal Cancer Taizhou Hanzhong biomedical co. LTD 190
Testing effectiveness (Phase 2)Ended earlyNCT05572684What this trial is testingA Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid TumorsWho this might be right forAdvanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more NextCure, Inc. 97
Large-scale testing (Phase 3)Study completedNCT02563002What this trial is testingStudy of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)Who this might be right forColorectal Carcinoma Merck Sharp & Dohme LLC 307
Testing effectiveness (Phase 2)Study completedNCT02178722What this trial is testingStudy to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected CancersWho this might be right forMicrosatellite-instability (MSI) High Colorectal Cancer (CRC)Endometrial CancerHead and Neck Cancer+11 more Incyte Corporation 444
Testing effectiveness (Phase 2)Active Not RecruitingNCT04802876What this trial is testingEfficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing TumorsWho this might be right forMSI-H Colorectal CancerMelanomaAnal Carcinoma+28 more SOLTI Breast Cancer Research Group 184
Early research (Phase 1)Ended earlyNCT04244552What this trial is testingA Phase 1b Trial of ATRC-101 in Adults With Advanced Solid MalignanciesWho this might be right forBreast CancerColorectal CancerOvarian Cancer+13 more Atreca, Inc. 87
Testing effectiveness (Phase 2)Active Not RecruitingNCT06640049What this trial is testingDostarlimab in Participants With Untreated Locally Advanced Rectal Cancer in ChinaWho this might be right forNeoplasms, Rectal GlaxoSmithKline 23
Testing effectiveness (Phase 2)UnknownNCT05429866What this trial is testingImmunological Variables Associated to ICI Toxicity in Cancer PatientsWho this might be right forBreast CancerMelanomaNon Small Cell Lung Cancer+10 more Jules Bordet Institute 441
Not applicableLooking for participantsNCT04643041What this trial is testingWatch and Wait in PD-1 Monoclonal Antibody Treated dMMR/MSI-H Distal Rectal CancerWho this might be right forRectal Cancer Sixth Affiliated Hospital, Sun Yat-sen University 47
Not applicableStudy completedNCT05871567What this trial is testingPredictive Value of DNA Mismatch Repair System in Colorectal CancersWho this might be right forMSI-H Colorectal Cancer University of Campania Luigi Vanvitelli 403
Testing effectiveness (Phase 2)Looking for participantsNCT07262619What this trial is testingEIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) TumorsWho this might be right forAdvanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more Eikon Therapeutics 160
Testing effectiveness (Phase 2)Study completedNCT02460198What this trial is testingStudy of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164)Who this might be right forColorectal Carcinoma Merck Sharp & Dohme LLC 124
Testing effectiveness (Phase 2)UnknownNCT03475953What this trial is testingA Phase I/II Study of Regorafenib Plus Avelumab in Solid TumorsWho this might be right forColorectal Cancer Not MSI-H or MMR-deficientGISTOesophageal or Gastric Carcinoma+12 more Institut Bergonié 747
Not applicableStudy completedNCT07263997What this trial is testingAssessment of a New Traction Device in Submucosal Dissection of Colorectal LesionsWho this might be right forColorectal Cancer (MSI-H) GCS Ramsay Santé pour l'Enseignement et la Recherche 30
Testing effectiveness (Phase 2)UnknownNCT03638297What this trial is testingPD-1 Antibody Combined With COX Inhibitor in MSI-H/dMMR or High TMB Colorectal CancerWho this might be right forColorectal Cancer Sun Yat-sen University 29
Testing effectiveness (Phase 2)Active Not RecruitingNCT02983578What this trial is testingDanvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal CancerWho this might be right forAdvanced Colorectal CarcinomaAdvanced Lung Non-Small Cell CarcinomaLung Non-Small Cell Carcinoma+22 more M.D. Anderson Cancer Center 39