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Results for “Microsatellite Stable”

176 trials

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Showing 20 of 176 results

Testing effectiveness (Phase 2)Study completedNCT04907539
What this trial is testing

Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)

Who this might be right for
Colorectal Cancer
Redx Pharma Ltd 25
Testing effectiveness (Phase 2)UnknownNCT03993626
What this trial is testing

A Trial of CXD101 in Combination With Nivolumab in Patients With Metastatic Microsatellite-Stable Colorectal Cancer

Who this might be right for
Colorectal Neoplasms Malignant
Celleron Therapeutics Ltd. 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT04017650
What this trial is testing

Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer

Who this might be right for
BRAF NP_004324.2:p.V600EMetastatic Colon AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+13 more
M.D. Anderson Cancer Center 38
Not applicableNot Yet RecruitingNCT06682247
What this trial is testing

A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Feng Wang 200
Testing effectiveness (Phase 2)Looking for participantsNCT05691491
What this trial is testing

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Who this might be right for
Advanced Malignant Solid NeoplasmAdvanced Microsatellite Stable Colorectal CarcinomaHematopoietic and Lymphatic System Neoplasm+4 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Active Not RecruitingNCT04361162
What this trial is testing

Nivolumab + Ipilimumab + Radiation in MSS Pancreatic Cancer

Who this might be right for
Pancreatic CancerMetastatic Pancreatic Cancer
Massachusetts General Hospital 30
Testing effectiveness (Phase 2)Study completedNCT03258398
What this trial is testing

Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer

Who this might be right for
Microsatellite Stable Relapsed or Refractory Colorectal Cancer
Effector Therapeutics 56
Testing effectiveness (Phase 2)Looking for participantsNCT06699836
What this trial is testing

Leronlimab in Combination With TAS-102 + Bevacizumab in Previously Treated Participants With mCRC

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
CytoDyn, Inc. 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06594692
What this trial is testing

Node-Sparing Short-Course Radiation with CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: a Randomized, Prospective, Multicenter Study

Who this might be right for
Microsatellite Stable (MSS) Colon CancerLocally Advanced Colon Cancer
Sir Run Run Shaw Hospital 140
Testing effectiveness (Phase 2)Looking for participantsNCT04895709
What this trial is testing

BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors

Who this might be right for
Cervical CancerGastric/Gastroesophageal Junction AdenocarcinomaMicrosatellite Stable Colorectal Cancer+8 more
Bristol-Myers Squibb 949
Testing effectiveness (Phase 2)Active Not RecruitingNCT03104439
What this trial is testing

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Who this might be right for
Microsatellite Stable Colorectal CancerPancreatic CancerMSI High Colorectal Cancer
Massachusetts General Hospital 84
Large-scale testing (Phase 3)Not Yet RecruitingNCT06832917
What this trial is testing

Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)

Who this might be right for
Rectal Cancer
Wan He 238
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07156682
What this trial is testing

QL1706 Plus XELOX as Neoadjuvant Therapy for MSS/pMMR Clinical Stage III Colon Cancer

Who this might be right for
Colon CancerMSS/pMMRQL1706
Qilu Hospital of Shandong University 21
Testing effectiveness (Phase 2)WithdrawnNCT05730673
What this trial is testing

Leronlimab in Combination With Regorafenib in Patients With CCR5+, Metastatic Colorectal Cancer

Who this might be right for
CCR5Microsatellite StableMetastatic+1 more
CytoDyn, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06206096
What this trial is testing

PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC

Who this might be right for
Colorectal CancerRAS MutationColorectal Neoplasms+1 more
Chinese PLA General Hospital 40
Early research (Phase 1)Active Not RecruitingNCT03891953
What this trial is testing

Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

Who this might be right for
Carcinoma, Non-Small-Cell LungMelanomaNasopharyngeal Carcinoma+2 more
Novartis Pharmaceuticals 98
Early research (Phase 1)Ended earlyNCT03189030
What this trial is testing

Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Aduro Biotech, Inc. 28
Early research (Phase 1)Ended earlyNCT04108481
What this trial is testing

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColon CancerMetastatic Colorectal Cancer+7 more
University of Iowa 5
Testing effectiveness (Phase 2)Looking for participantsNCT06356597
What this trial is testing

Tislelizumab With Fruquintinib, Metronidazole, in Mismatch Repair-proficient or Microsatellite Stability, Advanced Colorectal Cancer: a Multicenter, Single Arm, Clinical Trial

Who this might be right for
Colorectal Cancer
Jing-yuan Fang, MD, Ph. D 25
Testing effectiveness (Phase 2)Looking for participantsNCT07011550
What this trial is testing

Phase 2, Single-arm Trial of BMS-986340 in Association With Nivolumab, Trifluridine/Tipiracil and Bevacizumab for Patients Refractory to Standard of Care Treatment and With Microsatellite-stable Colorectal Cancer

Who this might be right for
Microsatellite-stable Colorectal CancerStandard of CareNivolumab+1 more
M.D. Anderson Cancer Center 40
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