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Results for “Microsatellite Stable (MSS) Colon Cancer”

74 trials

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Showing 20 of 74 results

Testing effectiveness (Phase 2)Study completedNCT03258398
What this trial is testing

Evaluate eFT508 Alone and in Combination With Avelumab in Subjects With MSS Colorectal Cancer

Who this might be right for
Microsatellite Stable Relapsed or Refractory Colorectal Cancer
Effector Therapeutics 56
Testing effectiveness (Phase 2)Looking for participantsNCT06699836
What this trial is testing

Leronlimab in Combination With TAS-102 + Bevacizumab in Previously Treated Participants With mCRC

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
CytoDyn, Inc. 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06594692
What this trial is testing

Node-Sparing Short-Course Radiation with CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: a Randomized, Prospective, Multicenter Study

Who this might be right for
Microsatellite Stable (MSS) Colon CancerLocally Advanced Colon Cancer
Sir Run Run Shaw Hospital 140
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07156682
What this trial is testing

QL1706 Plus XELOX as Neoadjuvant Therapy for MSS/pMMR Clinical Stage III Colon Cancer

Who this might be right for
Colon CancerMSS/pMMRQL1706
Qilu Hospital of Shandong University 21
Testing effectiveness (Phase 2)WithdrawnNCT05730673
What this trial is testing

Leronlimab in Combination With Regorafenib in Patients With CCR5+, Metastatic Colorectal Cancer

Who this might be right for
CCR5Microsatellite StableMetastatic+1 more
CytoDyn, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06206096
What this trial is testing

PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC

Who this might be right for
Colorectal CancerRAS MutationColorectal Neoplasms+1 more
Chinese PLA General Hospital 40
Early research (Phase 1)Ended earlyNCT03189030
What this trial is testing

Study of Personalized Immunotherapy in Adults With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Aduro Biotech, Inc. 28
Early research (Phase 1)Ended earlyNCT04108481
What this trial is testing

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColon CancerMetastatic Colorectal Cancer+7 more
University of Iowa 5
Very early researchLooking for participantsNCT07328087
What this trial is testing

COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColorectal Cancer Stage IIIColorectal Cancer Stage IV
Biogenea Pharmaceuticals Ltd. 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04599140
What this trial is testing

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Adenocarcinoma+18 more
M.D. Anderson Cancer Center 51
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
Testing effectiveness (Phase 2)Active Not RecruitingNCT04963283
What this trial is testing

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaColon CancerColon Adenocarcinoma+4 more
University of Colorado, Denver 48
Testing effectiveness (Phase 2)Study completedNCT03642067
What this trial is testing

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal AdenocarcinomasColorectal Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 59
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07281716
What this trial is testing

Combination Immunotherapy for the Treatment of Chemotherapy-refractory Metastatic MSS CRC

Who this might be right for
Metastatic Microsatellite Stable Colorectal Carcinoma
Dan Feng 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT04068610
What this trial is testing

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
MedImmune LLC 61
Testing effectiveness (Phase 2)Looking for participantsNCT07079631
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BioNTech SE 482
Early research (Phase 1)Ended earlyNCT06546553
What this trial is testing

Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

Who this might be right for
NeoplasmsNon-small-cell Lung CancerSquamous Cell Carcinoma of the Head and Neck+3 more
Pfizer 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07229872
What this trial is testing

A Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Fruquintinib in the Treatment of Immunodominant pMMR/MSS Metastatic Colorectal Cancer That Has Failed Second-line or Above Treatment

Who this might be right for
Colorectal Cancer
Harbin Medical University 18
Early research (Phase 1)Ended earlyNCT06448364
What this trial is testing

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination

Who this might be right for
Advanced or Metastatic Solid TumorsNon-Small Cell Lung CancerColorectal Cancer+2 more
Pfizer 4
Large-scale testing (Phase 3)Not Yet RecruitingNCT07132008
What this trial is testing

Neoadjuvant CAPOX Plus Tislelizumab vs CAPOX in MSS High-Risk Locally Advanced Colon Cancer

Who this might be right for
Colonic NeoplasmsNeoadjuvant TherapyImmune Checkpoint Inhibitors
First Affiliated Hospital of Guangxi Medical University 94
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