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Results for “Microsatellite Stable Colorectal Cancer”

165 trials

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Showing 20 of 165 results

Testing effectiveness (Phase 2)Study completedNCT03647839
What this trial is testing

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Australasian Gastro-Intestinal Trials Group 90
Early research (Phase 1)Looking for participantsNCT07321106
What this trial is testing

Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography Biosciences 80
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Testing effectiveness (Phase 2)UnknownNCT04724239
What this trial is testing

Sintilimab and Chidamide in Combination With or Without IBI305 in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
Advanced Microsatellite Stable Colorectal CancerMetastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 48
Testing effectiveness (Phase 2)Looking for participantsNCT06567782
What this trial is testing

Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer

Who this might be right for
Neoplasms, Colon
GlaxoSmithKline 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Very early researchLooking for participantsNCT07328087
What this trial is testing

COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColorectal Cancer Stage IIIColorectal Cancer Stage IV
Biogenea Pharmaceuticals Ltd. 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03104439
What this trial is testing

Nivolumab and Ipilimumab and Radiation Therapy in MSS and MSI High Colorectal and Pancreatic Cancer

Who this might be right for
Microsatellite Stable Colorectal CancerPancreatic CancerMSI High Colorectal Cancer
Massachusetts General Hospital 84
Testing effectiveness (Phase 2)Active Not RecruitingNCT04068610
What this trial is testing

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
MedImmune LLC 61
Early research (Phase 1)Looking for participantsNCT06654037
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

Who this might be right for
Metastatic Microsatellite Stable Colorectal CarcinomaRefractory Microsatellite Stable Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8
National Cancer Institute (NCI) 39
Testing effectiveness (Phase 2)WithdrawnNCT06575725
What this trial is testing

Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer

Who this might be right for
Advanced Colon AdenocarcinomaAdvanced Colorectal AdenocarcinomaAdvanced Rectal Adenocarcinoma+9 more
City of Hope Medical Center
Early research (Phase 1)Ended earlyNCT04609579
What this trial is testing

Study of SNX281 in Subjects With Advanced Solid Tumors and Lymphoma

Who this might be right for
Advanced Solid TumorAdvanced Lymphoma
Stingthera, Inc. 27
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06872606
What this trial is testing

Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal Cancer

Who this might be right for
Rectal Adenocarcinoma
Sir Run Run Shaw Hospital 33
Post-approval studies (Phase 4)UnknownNCT02887365
What this trial is testing

A Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon Cancer

Who this might be right for
MSI-L/MSSStage II Colon Cancer
National Taiwan University Hospital 300
Testing effectiveness (Phase 2)Study completedNCT02060188
What this trial is testing

Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread

Who this might be right for
Microsatellite Unstable Colorectal CancerMicrosatellite Stable Colorectal CancerMismatch Repair Proficient Colorectal Cancer+1 more
Bristol-Myers Squibb 385
Testing effectiveness (Phase 2)UnknownNCT04535024
What this trial is testing

The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Fudan University 60
Testing effectiveness (Phase 2)Looking for participantsNCT05963490
What this trial is testing

Regorafenib Alone or in Combination With Hypofractionated/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer

Who this might be right for
Microsatellite Stable Metastatic Colorectal Cancer
Fudan University 108
Testing effectiveness (Phase 2)Active Not RecruitingNCT06268015
What this trial is testing

Botensilimab and Balstilimab Optimization in Colorectal Cancer

Who this might be right for
Colorectal Cancer
Nicholas DeVito, MD 16
Testing effectiveness (Phase 2)WithdrawnNCT05178576
What this trial is testing

A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy

Who this might be right for
Colon Cancer
NSABP Foundation Inc
Early research (Phase 1)Ended earlyNCT04060342
What this trial is testing

GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic AdenocarcinomaEsophageal AdenocarcinomaEsophageal Squamous Cell Carcinoma+11 more
GB006, Inc., a wholly owned subsidiary of Gossamer Bio, Inc. 61
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