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Results for “Microsatellite Stable Rectal Carcinoma”

60 trials

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Showing 20 of 60 results

Testing effectiveness (Phase 2)WithdrawnNCT04119830
What this trial is testing

Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaMicrosatellite StableMismatch Repair Proficient+10 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Active Not RecruitingNCT04599140
What this trial is testing

SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Adenocarcinoma+18 more
M.D. Anderson Cancer Center 51
Early research (Phase 1)Looking for participantsNCT06654037
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

Who this might be right for
Metastatic Microsatellite Stable Colorectal CarcinomaRefractory Microsatellite Stable Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8
National Cancer Institute (NCI) 39
Early research (Phase 1)Ended earlyNCT04044430
What this trial is testing

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+25 more
University of California, San Francisco 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT05585814
What this trial is testing

CapeOX Combined With Bevacizumab Plus Anti-PD1 Antibody as Neoadjuvant Therapy for Microsatellite Stable Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Shanghai Changzheng Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT05771181
What this trial is testing

Vitamin E Combined With Fruquintinib and Tislelizumab in Microsatellite Stabilized Metastatic Colorectal Cancer Patients

Who this might be right for
Colorectal CancerMicrosatellite Stable Colorectal Carcinoma
Fudan University 25
Testing effectiveness (Phase 2)Study completedNCT03800602
What this trial is testing

Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaRefractory Colorectal Carcinoma+5 more
Emory University 29
Testing effectiveness (Phase 2)Study completedNCT03642067
What this trial is testing

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal AdenocarcinomasColorectal Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 59
Testing effectiveness (Phase 2)WithdrawnNCT03576963
What this trial is testing

Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaCpG Island Methylator PhenotypeMetastatic Microsatellite Stable Colorectal Carcinoma+5 more
University of Southern California
Early research (Phase 1)Active Not RecruitingNCT06544655
What this trial is testing

BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 213
Early research (Phase 1)Study completedNCT05130060
What this trial is testing

A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Colorectal Carcinoma+8 more
Mayo Clinic 15
Testing effectiveness (Phase 2)Study completedNCT03102047
What this trial is testing

Study of Durvalumab (MEDI4736) After Chemo-Radiation for Microsatellite Stable Stage II-IV Rectal Cancer

Who this might be right for
Rectal Cancer
NSABP Foundation Inc 45
Large-scale testing (Phase 3)Not Yet RecruitingNCT07551479
What this trial is testing

SCRT Based iTNT vs. LCRT Based TNT for MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)MSS (Microsatellite Stable)
Fudan University 612
Testing effectiveness (Phase 2)Looking for participantsNCT07735624
What this trial is testing

RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer

Who this might be right for
Early Rectal CancerStage I Rectal CancerMicrosatellite Stable Rectal Carcinoma
Dana-Farber Cancer Institute 16
Testing effectiveness (Phase 2)Ended earlyNCT05572684
What this trial is testing

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants With Advanced Unresectable or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsMicrosatellite Instability LowMicrosatellite Instability High+9 more
NextCure, Inc. 97
Not applicableActive Not RecruitingNCT06688786
What this trial is testing

A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 30
Testing effectiveness (Phase 2)Looking for participantsNCT07150949
What this trial is testing

Long-course Chemoradiotherapy or Short-course Radiotherapy Combined With CAPOX, PD-1antibody, and COX-2 Inhibitor for MSS Locally Advanced Rectal Cancer (SERRAC)

Who this might be right for
Locally Advanced Rectal CancerNeoadjuvant Therapy
Fudan University 138
Testing effectiveness (Phase 2)Looking for participantsNCT05136326
What this trial is testing

Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal Cancer

Who this might be right for
Rectal Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT05627635
What this trial is testing

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+4 more
City of Hope Medical Center 20
Testing effectiveness (Phase 2)WithdrawnNCT06730100
What this trial is testing

CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer

Who this might be right for
Metastatic Mismatch Repair Proficient Colorectal CarcinomaRefractory Mismatch Repair Proficient Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8
National Cancer Institute (NCI)
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