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Results for “Microsatellite Stable Rectal Carcinoma”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT07540572
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

Who this might be right for
ER+, HER 2- Breast CancerNon-small Cell Lung Cancer (NSCLC)Castration-resistant Prostate Cancer (CRPC)+1 more
IDEAYA Biosciences 160
Testing effectiveness (Phase 2)Looking for participantsNCT07594925
What this trial is testing

Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial

Who this might be right for
Rectal Cancer
Tianjin Medical University Cancer Institute and Hospital 130
Large-scale testing (Phase 3)Not Yet RecruitingNCT06832917
What this trial is testing

Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)

Who this might be right for
Rectal Cancer
Wan He 238
Testing effectiveness (Phase 2)WithdrawnNCT05518032
What this trial is testing

Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)

Who this might be right for
Metastatic Microsatellite Stable Colorectal CarcinomaRecurrent Colorectal CarcinomaStage III Colorectal Cancer AJCC v8+2 more
Roswell Park Cancer Institute
Early research (Phase 1)Not Yet RecruitingNCT07363408
What this trial is testing

Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer

Who this might be right for
Advanced Microsatellite Stable Colorectal CarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaStage III Colorectal Cancer AJCC v8+1 more
City of Hope Medical Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT05576480
What this trial is testing

SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer

Who this might be right for
Rectal CancerLocally Advanced
Ruijin Hospital 55
Testing effectiveness (Phase 2)Active Not RecruitingNCT04963283
What this trial is testing

Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaColon CancerColon Adenocarcinoma+4 more
University of Colorado, Denver 48
Testing effectiveness (Phase 2)Active Not RecruitingNCT03983993
What this trial is testing

Niraparib and Panitumumab in Patients With Advanced or Metastatic Colorectal Cancer

Who this might be right for
Advanced Microsatellite Stable Colorectal CarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaMicrosatellite Stable+3 more
Emory University 26
Testing effectiveness (Phase 2)Looking for participantsNCT06522919
What this trial is testing

Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticMicrosatellite Stable Colorectal CarcinomaRefractory Mismatch-repair-proficient (pMMR) Metastatic Colorectal Cancer
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Early research (Phase 1)UnknownNCT04432857
What this trial is testing

AN0025 and Pembrolizumab Combination in Advanced Solid Tumors

Who this might be right for
Triple-negative Breast CancerNSCLC, Squamous or Non-SquamousUrothelial Carcinoma of the Bladder+2 more
Adlai Nortye Biopharma Co., Ltd. 63
Testing effectiveness (Phase 2)Looking for participantsNCT06850103
What this trial is testing

SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases

Who this might be right for
Colorectal CarcinomaOligometastasespMMR+2 more
First Affiliated Hospital of Zhejiang University 51
Testing effectiveness (Phase 2)Active Not RecruitingNCT05308446
What this trial is testing

Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Rectal AdenocarcinomaStage III Colon Cancer AJCC v8+5 more
National Cancer Institute (NCI) 86
Testing effectiveness (Phase 2)UnknownNCT06206096
What this trial is testing

PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC

Who this might be right for
Colorectal CancerRAS MutationColorectal Neoplasms+1 more
Chinese PLA General Hospital 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT05672316
What this trial is testing

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

Who this might be right for
Advanced Colorectal AdenocarcinomaAdvanced Microsatellite Stable Colorectal CarcinomaMetastatic Colorectal Adenocarcinoma+3 more
City of Hope Medical Center 28
Testing effectiveness (Phase 2)UnknownNCT05980689
What this trial is testing

Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Sun Yat-sen University 33
Large-scale testing (Phase 3)Not Yet RecruitingNCT07277842
What this trial is testing

PD-1 + FOLFOXIRI vs CAPOX as Total Neoadjuvant Therapy for pMMR Low Rectal Cancer

Who this might be right for
Locally Advanced Low Rectal AdenocarcinomapMMR (Microsatellite Stable Rectal Cancer)
Sun Yat-sen University 382
Testing effectiveness (Phase 2)Looking for participantsNCT06864013
What this trial is testing

SCRT Combined With Chemotherapy and Iparomlimab and Tuvonralimab in MSS or pMMR Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
First Affiliated Hospital of Zhejiang University 116
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07381400
What this trial is testing

Neoadjuvant mFOLFOX6 Chemotherapy Combined With Anti-PD-1 Therapy in MSS/pMMR Locally Advanced Rectal Cancer (FIRM02 Study)

Who this might be right for
Rectal Cancer
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 128
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05359393
What this trial is testing

A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal Metastasis

Who this might be right for
Advanced Rectal CancerLiver MetastasisPulmonary Metastasis+1 more
Fudan University 52
Testing effectiveness (Phase 2)WithdrawnNCT05582031
What this trial is testing

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers

Who this might be right for
Anal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more
Translational Research in Oncology
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