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Results for “Midline Diffuse Glioma”

70 trials

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Showing 20 of 70 results

Not applicableNo Longer AvailableNCT05518838
What this trial is testing

Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-altered

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine Glioma
Oblato, Inc.
Testing effectiveness (Phase 2)Study completedNCT02960230
What this trial is testing

H3.3K27M Peptide Vaccine With Nivolumab for Children With Newly Diagnosed DIPG and Other Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGliomaDiffuse Midline Glioma, H3 K27M-Mutant
Sabine Mueller, MD, PhD 50
Early research (Phase 1)Looking for participantsNCT06894979
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group 54
Testing effectiveness (Phase 2)Ended earlyNCT02525692
What this trial is testing

Oral ONC201 in Adult Recurrent Glioblastoma

Who this might be right for
GlioblastomaDiffuse Midline GliomaH3 K27M Glioma+3 more
Jazz Pharmaceuticals 84
Testing effectiveness (Phase 2)Ended earlyNCT02758366
What this trial is testing

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Who this might be right for
Glioblastoma (GBM)DIPGBrainstem Glioma, Pediatric+5 more
Meyer Children's Hospital IRCCS 21
Not applicableNo Longer AvailableNCT06439849
What this trial is testing

Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline Glioma

Who this might be right for
DIPG Brain TumorDiffuse Brainstem GliomaH3 K27M+2 more
Petrov, Andrey
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Early research (Phase 1)Study completedNCT00020579
What this trial is testing

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

Who this might be right for
Cancer
National Institutes of Health Clinical Center (CC) 75
Testing effectiveness (Phase 2)Temporarily pausedNCT05123534
What this trial is testing

Sonodynamic Therapy Using SONALA-001 and Exablate 4000 Type 2.0 in Patients with DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma
SonALAsense, Inc. 15
Not applicableLooking for participantsNCT06000787
What this trial is testing

MCT for the Harvard/UCSF ROBIN Center

Who this might be right for
Glioma, Childhood BrainstemNeuroblastoma
Brigham and Women's Hospital 47
Not applicableLooking for participantsNCT06140719
What this trial is testing

XPedite: A Study to Expedite DIPG and DMG Research

Who this might be right for
OncologyDIPGDMG
xCures 400
Large-scale testing (Phase 3)Looking for participantsNCT05580562
What this trial is testing

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

Who this might be right for
H3 K27MGlioma
Jazz Pharmaceuticals 510
Early research (Phase 1)Looking for participantsNCT05835687
What this trial is testing

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Who this might be right for
Central Nervous System NeoplasmsAtypical Teratoid/Rhabdoid TumorDiffuse Midline Glioma, H3 K27M-Mutant+4 more
St. Jude Children's Research Hospital 48
Early research (Phase 1)Looking for participantsNCT04541082
What this trial is testing

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Who this might be right for
Central Nervous System NeoplasmsGlioblastomaGliosarcoma, Adult+20 more
Jazz Pharmaceuticals 102
Not applicableNot Yet RecruitingNCT06093165
What this trial is testing

RE-irradiation of Diffuse MIdline Glioma paTients

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine GliomaDiffuse Glioma+3 more
Rigshospitalet, Denmark 59
Early research (Phase 1)Looking for participantsNCT05544526
What this trial is testing

CAR T Cells to Target GD2 for DMG

Who this might be right for
Diffuse Midline Glioma, H3 K27M-Mutant
University College, London 12
Not applicableNot Yet RecruitingNCT07020052
What this trial is testing

Phase II Exploratory Study of Sequential Triple Therapy (Temozolomide/Anlotinib/Bemarituzumab) in Combination With Concurrent Radiotherapy With Temozolomide and Anlotinib for the Maintenance Treatment of Diffuse Midline Gliomas in Children

Who this might be right for
Maintenance Treatment of Diffuse Midline Gliomas in Children
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 33
Early research (Phase 1)Looking for participantsNCT06305910
What this trial is testing

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantRecurrent High Grade Glioma
OX2 Therapeutics 24
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Early research (Phase 1)Not Yet RecruitingNCT07455045
What this trial is testing

A Phase I Study of FZ-AD005 in Patients With High-Grade Glioma (HGG)

Who this might be right for
High Grade Glioma (III or IV)Diffuse Midline Glioma (DMG)Glioblastoma (GBM)
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. 40
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