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Results for “Mild Hepatic Dysfunction”

26 trials

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Showing 20 of 26 results

Not applicableLooking for participantsNCT07454824
What this trial is testing

E-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

Who this might be right for
DementiaPotentially Inappropriate Medication UseMild Cognitive Impairment (MCI)
Johns Hopkins University 100
Early research (Phase 1)Study completedNCT06916078
What this trial is testing

Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function

Who this might be right for
Liver DysfunctionHealthy
Eli Lilly and Company 30
Early research (Phase 1)Study completedNCT00118170
What this trial is testing

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Adult Burkitt Lymphoma+42 more
National Cancer Institute (NCI) 150
Early research (Phase 1)Ended earlyNCT05126329
What this trial is testing

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 13
Early research (Phase 1)Looking for participantsNCT07600788
What this trial is testing

A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function.

Who this might be right for
Chronic Hepatitis B
Ausper Biopharma Co., Ltd. 32
Early research (Phase 1)Study completedNCT00416702
What this trial is testing

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Who this might be right for
Hepatic Insufficiency
Novartis 32
Not applicableStudy completedNCT02992639
What this trial is testing

Weight Loss Effect on Circulating Liver Enzymes

Who this might be right for
Visceral FatLiver Dysfunction
Yonsei University 80
Early research (Phase 1)Study completedNCT00025415
What this trial is testing

Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAIDS-related Peripheral/Systemic Lymphoma+78 more
National Cancer Institute (NCI) 60
Early research (Phase 1)Study completedNCT01571388
What this trial is testing

Compare Pharmacokinetics Of Dacomitinib (PF-00299804) Between Healthy Subjects And Subjects With Mild And Moderate Hepatic Impairment

Who this might be right for
HealthyOtherwise Healthy Volunteers With Mild or Moderate Hepatic Dysfunction
Pfizer 25
Not applicableStudy completedNCT06509373
What this trial is testing

A Portal-based Advance Care Planning Intervention Among Community-Dwelling Persons Living With Cognitive Impairment

Who this might be right for
Advanced Care Planning
Wake Forest University Health Sciences 300
Early research (Phase 1)Study completedNCT04123769
What this trial is testing

Study on PK of Hydronidone in Patients and Special Population

Who this might be right for
Hepatitis b & Liver Dysfunction
Beijing Continent Pharmaceutical Co, Ltd. 8
Early research (Phase 1)Study completedNCT05718258
What this trial is testing

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 26
Early research (Phase 1)UnknownNCT06176716
What this trial is testing

Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride

Who this might be right for
Hepatic Insufficiency
Ahon Pharmaceutical Co., Ltd. 24
Early research (Phase 1)Study completedNCT06444204
What this trial is testing

Evaluate the Effect of Mild and Moderate Hepatic Impairment on the Single-Dose Pharmacokinetics of Rilzabrutinib (PRN1008)

Who this might be right for
Hepatic Function AbnormalHealthy Volunteers
Principia Biopharma, a Sanofi Company 29
Early research (Phase 1)Study completedNCT05283915
What this trial is testing

Study to Assess the Plasma Concentration of Tolebrutinib Given as a Tablet to Adult Participants With Mild Hepatic Impairment Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 10
Early research (Phase 1)Study completedNCT00437424
What this trial is testing

Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction

Who this might be right for
Carcinoma, Hepatocellular
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT05607173
What this trial is testing

A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment

Who this might be right for
Hepatic Function Abnormal
Sanofi 21
Early research (Phase 1)Study completedNCT00608361
What this trial is testing

Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery

Who this might be right for
Adult Acute Lymphoblastic Leukemia in RemissionAdult B Acute Lymphoblastic LeukemiaAdult Hepatocellular Carcinoma+82 more
National Cancer Institute (NCI) 80
Early research (Phase 1)Study completedNCT00499811
What this trial is testing

Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction

Who this might be right for
Adult Grade III Lymphomatoid GranulomatosisAdult Nasal Type Extranodal NK/T-cell LymphomaAnaplastic Large Cell Lymphoma+60 more
National Cancer Institute (NCI) 15
Early research (Phase 1)Study completedNCT01358565
What this trial is testing

Pharmacokinetics Of Orally Administered Fx-1006A In Subjects With Hepatic Dysfunction

Who this might be right for
Mild Hepatic DysfunctionModerate Hepatic Dysfunction
Pfizer 16
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