Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Mild Hypercortisolism”

12 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 12 of 12 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06106295
What this trial is testing

Metyrapone for Mild Autonomous Cortisol Secretion (MACS)

Who this might be right for
Autonomous Cortisol SecretionMild Autonomous Cortisol Secretion (MACS)
Mayo Clinic 30
Not applicableNot Yet RecruitingNCT07361874
What this trial is testing

IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion

Who this might be right for
Mild Autonomous Cortisol Secretion (MACS)Autonomous Cortisol Secretion (ACS)Subclinical Cushing's+1 more
University of Texas Southwestern Medical Center 75
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07138274
What this trial is testing

Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS

Who this might be right for
Mild Autonomous Cortisol Secretion (MACS)Autonomous Cortisol Secretion (ACS)
Mayo Clinic 90
Post-approval studies (Phase 4)Looking for participantsNCT07247058
What this trial is testing

Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)

Who this might be right for
Mild Autonomous Cortisol Secretion (MACS)
Johns Hopkins University 10
Post-approval studies (Phase 4)Looking for participantsNCT06801249
What this trial is testing

Effect of Metyrapone on Cardiovascular Risk Factors in Patients With Adrenal Incidentalomas and Cushing's Syndrome

Who this might be right for
Adrenal IncidentalomasCushing Syndrome
IRCCS Azienda Ospedaliero-Universitaria di Bologna 50
Not applicableActive Not RecruitingNCT05255900
What this trial is testing

Effects of Metyrapone in Patients With Hypercortisolism

Who this might be right for
Hypercortisolism
Istituto Auxologico Italiano 20
Testing effectiveness (Phase 2)Looking for participantsNCT07104812
What this trial is testing

Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)

Who this might be right for
Mild Autonomous Cortisol SecretionAutonomous Cortisol Secretion (ACS)
Mayo Clinic 15
Post-approval studies (Phase 4)Ended earlyNCT05038878
What this trial is testing

An Oral GnRH Antagonist to Treat Mild Autonomous Cortisol Excess (MACE) Due to Adrenal Adenomas in Postmenopausal Women

Who this might be right for
Mild Autonomous Cortisol Excess
Icahn School of Medicine at Mount Sinai 4
Not applicableLooking for participantsNCT07304674
What this trial is testing

The Association Between Primary Aldosteronism and Cognitive Dysfunction

Who this might be right for
Primary AldosteronismCognitive DysfunctionMild Cognitive Impairment (MCI)+1 more
Xinjiang Medical University 1,000
Post-approval studies (Phase 4)Study completedNCT01990560
What this trial is testing

Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism

Who this might be right for
Mild Hypercortisolism
Icahn School of Medicine at Mount Sinai 8
Not applicableLooking for participantsNCT04543253
What this trial is testing

Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)

Who this might be right for
Cushing Syndrome
Mayo Clinic 700
Not applicableEnded earlyNCT01246739
What this trial is testing

Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome

Who this might be right for
Adrenal Tumour With Mild Hypercortisolism
Region Skane 34