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Results for “Mismatch Repair-Deficient Gastric Cancer”

23 trials

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Showing 20 of 23 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04556253
What this trial is testing

AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer

Who this might be right for
MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Peking University 47
Not applicableNot Yet RecruitingNCT07625735
What this trial is testing

MMR Status Modulates the Predictive Value of Lymphatic Invasion for Lymph Node Metastasis in Gastric Cancer

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMismatch Repair Deficient or MSI-High Solid TumorsLymph Node Metastasis+1 more
Shanghai Zhongshan Hospital 3,000
Testing effectiveness (Phase 2)Enrolling By InvitationNCT07542262
What this trial is testing

Low-dose Immunotherapy in Metastatic and Locally Advanced Colorectal and Gastric MSI/dMMR Cancers

Who this might be right for
Colorectal CancerGastric Cancer
Blokhin's Russian Cancer Research Center 128
Testing effectiveness (Phase 2)Looking for participantsNCT06580574
What this trial is testing

Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers

Who this might be right for
Gastric CancerColon CancerMSI-H+1 more
Peking University 34
Not applicableLooking for participantsNCT07829081
What this trial is testing

Research on Effective Strategies After Immunotherapy for Mismatch Repair-deficient Early-stage GI Tumors

Who this might be right for
Quality of Life (QOL)Mismatch Repair Deficient Colorectal CancerMicrosatellite Instability-High Colorectal Cancer+8 more
University Hospital, Basel, Switzerland 234
Early research (Phase 1)Study completedNCT03652077
What this trial is testing

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Who this might be right for
Cervical CancerGastric CancerStomach Cancer+18 more
Incyte Corporation 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07595523
What this trial is testing

Iparomlimab Tolvorlimab as Neoadjuvant Immunotherapy for Locally Advanced Gastric Adenocarcinoma With Microsatellite Instability/Mismatch Repair Deficiency

Who this might be right for
Gastric Cancer
Peking University Cancer Hospital & Institute 30
Not applicableLooking for participantsNCT03452774
What this trial is testing

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

Who this might be right for
Cancer, MetastaticCancerCancer of Pancreas+40 more
Massive Bio, Inc. 50,000
Early research (Phase 1)Study completedNCT03894618
What this trial is testing

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Who this might be right for
Squamous Cell Carcinoma of the Head and NeckMelanomaNon Small Cell Lung Cancer+10 more
Shattuck Labs, Inc. 49
Early research (Phase 1)Study completedNCT02635672
What this trial is testing

Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Vincerx Pharma, Inc. 110
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06426654
What this trial is testing

Sintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric Cancer

Who this might be right for
Gastric Cancer
West China Hospital 45
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07266025
What this trial is testing

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Who this might be right for
Gastric AdenocarcinomaGastroesophageal AdenocarcinomaMismatch Repair Deficient or MSI-High Solid Tumors+1 more
Shanghai Zhongshan Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT07262619
What this trial is testing

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Who this might be right for
Advanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more
Eikon Therapeutics 160
Testing effectiveness (Phase 2)UnknownNCT03475953
What this trial is testing

A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors

Who this might be right for
Colorectal Cancer Not MSI-H or MMR-deficientGISTOesophageal or Gastric Carcinoma+12 more
Institut Bergonié 747
Testing effectiveness (Phase 2)Active Not RecruitingNCT03257163
What this trial is testing

Pembrolizumab, Capecitabine, and Radiation Therapy in Treating Patients With Mismatch-Repair Deficient and Epstein-Barr Virus Positive Gastric Cancer

Who this might be right for
Epstein-Barr Virus PositiveGastric AdenocarcinomaMismatch Repair Protein Deficiency+8 more
Rutgers, The State University of New Jersey 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07259473
What this trial is testing

Factors Influencing Immunotherapy Response in dMMR/MSI-H Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMismatch Repair Deficient or MSI-High Solid TumorsImmunotherapy
Shanghai Zhongshan Hospital 15
Testing effectiveness (Phase 2)Temporarily pausedNCT06250036
What this trial is testing

Zimberelimab Anti-PD1 +/- Domvanalimab in Resectable Mmrd Gastric Cancer

Who this might be right for
Locally Advanced Gastric AdenocarcinomaMSI-H/dMMR Gastric CancerMSI-H/dMMR Gastroesophageal-junction Cancer
Royal Marsden NHS Foundation Trust 50
Testing effectiveness (Phase 2)Looking for participantsNCT06047379
What this trial is testing

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Who this might be right for
Diffuse Astrocytoma, IDH-MutantGlioblastoma, IDH-wildtypeBrain Metastases, Adult+18 more
Neonc Technologies, Inc. 134
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Testing effectiveness (Phase 2)Active Not RecruitingNCT03228667
What this trial is testing

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

Who this might be right for
Non-Small Cell Lung CancerSmall Cell Lung CancerUrothelial Carcinoma+10 more
ImmunityBio, Inc. 40
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