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Results for “Mismatch Repair-proficient”

52 trials

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Showing 20 of 52 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05609370
What this trial is testing

A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer

Who this might be right for
Unresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal Cancer
BeiGene 113
Testing effectiveness (Phase 2)Looking for participantsNCT06856837
What this trial is testing

- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases

Who this might be right for
Metastatic Colorectal Cancer
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 140
Testing effectiveness (Phase 2)Looking for participantsNCT06843434
What this trial is testing

Botensilimab and Balstilimab for Rectal Adenocarcinoma

Who this might be right for
Microsatellite Stable Rectal CarcinomaLocally Advanced Rectal Adenocarcinoma
Memorial Sloan Kettering Cancer Center 40
Testing effectiveness (Phase 2)Ended earlyNCT05263492
What this trial is testing

Study of Lenvatinib w/ Pembro in Black Participants w/Mismatch Repair-Prof Recurrent Endometrial Cancer

Who this might be right for
Endometrial CancerMismatch Repair-ProficientRecurrent Endometrial Cancer
Virginia Commonwealth University 4
Testing effectiveness (Phase 2)UnknownNCT05933980
What this trial is testing

Toripalimab,Celecoxib and Regorafenib in the Treatment of Refractory Advanced Colorectal Cancer

Who this might be right for
Colorectal CancerLiver MetastasesMSS
Sun Yat-sen University 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT05205330
What this trial is testing

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

Who this might be right for
Refractory Metastatic Colorectal CancerSolid TumorMetastatic Microsatellite-stable Colorectal Cancer+3 more
Rottapharm Biotech 107
Testing effectiveness (Phase 2)Looking for participantsNCT06792695
What this trial is testing

Novel Study Interventions and Combinations in Participants With Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
AstraZeneca 120
Testing effectiveness (Phase 2)Looking for participantsNCT06850103
What this trial is testing

SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases

Who this might be right for
Colorectal CarcinomaOligometastasespMMR+2 more
First Affiliated Hospital of Zhejiang University 51
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07580339
What this trial is testing

Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer

Who this might be right for
Rectal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 30
Testing effectiveness (Phase 2)Study completedNCT04126733
What this trial is testing

Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)

Who this might be right for
Colorectal Cancer
Bayer 70
Testing effectiveness (Phase 2)Ended earlyNCT05609656
What this trial is testing

Electroporation and Immunotherapy in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Ismail Gögenur 4
Testing effectiveness (Phase 2)WithdrawnNCT04119830
What this trial is testing

Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaMicrosatellite StableMismatch Repair Proficient+10 more
Roswell Park Cancer Institute
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07621562
What this trial is testing

Tafolecimab Combined With Sintilimab and SOX in the Treatment of pMMR/MSS Gastric Cancer

Who this might be right for
Gastric AdenocarcinomaEsophagogastric Juction CancerProficient Mismatch Repair
First Affiliated Hospital of Zhejiang University 30
Testing effectiveness (Phase 2)WithdrawnNCT06730100
What this trial is testing

CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer

Who this might be right for
Metastatic Mismatch Repair Proficient Colorectal CarcinomaRefractory Mismatch Repair Proficient Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Ended earlyNCT05733611
What this trial is testing

RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

Who this might be right for
Refractory Metastatic Colorectal CancerpMMRMSS
Replimune, Inc. 5
Large-scale testing (Phase 3)Not Yet RecruitingNCT06832917
What this trial is testing

Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)

Who this might be right for
Rectal Cancer
Wan He 238
Early research (Phase 1)Study completedNCT03712943
What this trial is testing

Regorafenib and Nivolumab in Mismatch Repair (MMR) Refractory Colorectal Cancer

Who this might be right for
Colorectal CancerMetastatic Colorectal CancerColon Cancer
H. Lee Moffitt Cancer Center and Research Institute 52
Testing effectiveness (Phase 2)Study completedNCT02437136
What this trial is testing

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)

Who this might be right for
Non-Small Cell Lung CancerMelanomaMismatch Repair-Proficient Colorectal Cancer
Syndax Pharmaceuticals 191
Testing effectiveness (Phase 2)Looking for participantsNCT07244705
What this trial is testing

ABT-301 Plus Tislelizumab With Bevacizumab in pMMR/Non-MSI-H Locally Advanced or mCRC

Who this might be right for
Colorectal Cancer (Diagnosis)Colorectal Cancer MetastaticColorectal Cancer (CRC)+1 more
Anbogen Therapeutics, Inc. 66
Testing effectiveness (Phase 2)Study completedNCT03396926
What this trial is testing

Pembrolizumab, Capecitabine, and Bevacizumab for Treating Colorectal Cancer

Who this might be right for
Microsatellite StableMismatch Repair Protein ProficientStage III Colorectal Cancer AJCC v7+5 more
University of California, San Francisco 44
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