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Results for “Mitochondrial DNA Depletion”

7 trials

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Showing 7 of 7 results

Not applicableLooking for participantsNCT07775872
What this trial is testing

Prospective Natural History Study of POLG Disease

Who this might be right for
PolG, Primary Mitochondrial Myopathy
The POLG Foundation 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT03639701
What this trial is testing

Treatment of TK2 Deficiency With Thymidine and Deoxycytidine

Who this might be right for
Mitochondrial DNA Depletion Syndrome 2 Myopathic TypeThymidine Kinase 2 Deficiency
Columbia University 23
Large-scale testing (Phase 3)Study completedNCT05162768
What this trial is testing

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)

Who this might be right for
Mitochondrial MyopathiesMitochondrial PathologyMitochondrial DNA Mutation+5 more
Stealth BioTherapeutics Inc. 102
Testing effectiveness (Phase 2)Looking for participantsNCT06754098
What this trial is testing

Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency

Who this might be right for
Thymidine Kinase 2 (TK2 ) DeficiencyMitochondrial Myopathies
Cristina Domínguez González 15
Testing effectiveness (Phase 2)Looking for participantsNCT04802707
What this trial is testing

Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome

Who this might be right for
Mitochondrial DiseasesMitochondrial EncephalomyopathyMitochondrial Encephalopathy+2 more
Kenneth Myers, MD 200
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Not applicableEnrolling By InvitationNCT06938542
What this trial is testing

Palliative Care Needs of Children With Rare Diseases and Their Families

Who this might be right for
Trisomy 13 SyndromeArthrogryposis Congenita Multiplex With Intestinal AtresiaAsparagine Synthetase Deficiency+16 more
Children's National Research Institute 480