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Results for “Mitochondrial Depletion Disorder”

11 trials

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Showing 11 of 11 results

Not applicableLooking for participantsNCT07775872
What this trial is testing

Prospective Natural History Study of POLG Disease

Who this might be right for
PolG, Primary Mitochondrial Myopathy
The POLG Foundation 300
Not applicableStudy completedNCT05017818
What this trial is testing

A Retrospective Study of Subjects With Thymidine Kinase 2 Deficiency

Who this might be right for
Thymidine Kinase 2 Deficiency
Zogenix MDS, Inc. 61
Large-scale testing (Phase 3)Study completedNCT05162768
What this trial is testing

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)

Who this might be right for
Mitochondrial MyopathiesMitochondrial PathologyMitochondrial DNA Mutation+5 more
Stealth BioTherapeutics Inc. 102
Testing effectiveness (Phase 2)Looking for participantsNCT06754098
What this trial is testing

Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency

Who this might be right for
Thymidine Kinase 2 (TK2 ) DeficiencyMitochondrial Myopathies
Cristina Domínguez González 15
Testing effectiveness (Phase 2)Looking for participantsNCT04802707
What this trial is testing

Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome

Who this might be right for
Mitochondrial DiseasesMitochondrial EncephalomyopathyMitochondrial Encephalopathy+2 more
Kenneth Myers, MD 200
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Large-scale testing (Phase 3)WithdrawnNCT04581733
What this trial is testing

The Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)

Who this might be right for
Thymidine Kinase 2 Deficiency
Zogenix MDS, Inc.
Not applicableEnrolling By InvitationNCT01803906
What this trial is testing

Tissue Sample Study for Mitochondrial Disorders

Who this might be right for
Mitochondrial DisordersMitochondrial DiseaseMelas+6 more
Columbia University 6,900
Testing effectiveness (Phase 2)Study completedNCT03845712
What this trial is testing

An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency

Who this might be right for
Thymidine Kinase 2 Deficiency
UCB BIOSCIENCES, Inc. 47
Not applicableEnrolling By InvitationNCT06938542
What this trial is testing

Palliative Care Needs of Children With Rare Diseases and Their Families

Who this might be right for
Trisomy 13 SyndromeArthrogryposis Congenita Multiplex With Intestinal AtresiaAsparagine Synthetase Deficiency+16 more
Children's National Research Institute 480
Not applicableStudy completedNCT07467889
What this trial is testing

Impact of CRRT on Serum Carnitine and Micronutrient Levels

Who this might be right for
Acute Kidney Injury (Nontraumatic)Critical Illness
Gulhane Training and Research Hospital 43