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Results for “Mitochondrial Disease”

857 trials

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Showing 20 of 857 results

Not applicableStudy completedNCT03464500
What this trial is testing

AMAZ-02 Effect on Exercise ToLerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial)

Who this might be right for
Muscle Function, Mitochondrial FunctionOverweightHealthy Aging
Amazentis SA 90
Not applicableStudy completedNCT06784453
What this trial is testing

Evolution of Nutritional Status and Intestinal Function in Patients With MNGIE

Who this might be right for
Mitochondrial Neurogastrointestinal Encephalopathy Disease
IRCCS Azienda Ospedaliero-Universitaria di Bologna 8
Early research (Phase 1)Ended earlyNCT00060515
What this trial is testing

RG2133 (2',3',5'-Tri-O-Acetyluridine) in Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Repligen Corporation 12
Not applicableActive Not RecruitingNCT01911091
What this trial is testing

Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus)

Who this might be right for
ObesityDisorder of Lipid Storage and MetabolismLipid Metabolism Disorders+1 more
AdventHealth Translational Research Institute 56
Not applicableNo Longer AvailableNCT04381091
What this trial is testing

Expanded Access Program for Idebenone in Patients With Leber's Hereditary Optic Neuropathy Who Completed the LEROS Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Not applicableLooking for participantsNCT06483490
What this trial is testing

Environmental Pollutants in COPD and Lung Cancer

Who this might be right for
COPD and Lung Cancer
University of Campania Luigi Vanvitelli 200
Testing effectiveness (Phase 2)Ended earlyNCT02976038
What this trial is testing

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 28
Not applicableLooking for participantsNCT05522374
What this trial is testing

TIRCON International NBIA Registry

Who this might be right for
Neurodegeneration With Brain Iron Accumulation (NBIA)Pantothenate Kinase-associated Neurodegeneration (PKAN)Beta-Propeller Protein-Associated Neurodegeneration (BPAN)+8 more
LMU Klinikum 2,000
Not applicableStudy completedNCT01776918
What this trial is testing

Energy Requirements in Mitochondrial Disease

Who this might be right for
Mitochondrial DiseaseChronic Metabolic Disorder
University of British Columbia 23
Very early researchStudy completedNCT02697201
What this trial is testing

Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D)

Who this might be right for
Insulin Resistance
Pennington Biomedical Research Center 25
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Testing effectiveness (Phase 2)Looking for participantsNCT05526144
What this trial is testing

Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans

Who this might be right for
Nonalcoholic SteatohepatitisLiver Fibrosis
VA Office of Research and Development 128
Not applicableStudy completedNCT01625663
What this trial is testing

Heart and Muscle Metabolism in Barth Syndrome

Who this might be right for
Barth Syndrome
Duke University 64
Testing effectiveness (Phase 2)Study completedNCT02805790
What this trial is testing

Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 30
Not applicableStudy completedNCT04126551
What this trial is testing

Mitochondrial Methylation in Type 2 Diabetes

Who this might be right for
OverweightObesityDiabetes Mellitus, Type 2+1 more
University of Arizona 27
Not applicableWithdrawnNCT03514875
What this trial is testing

Effects of Mitochondrial-targeted Antioxidant on Mild Cognitive Impairment (MCI) Patients

Who this might be right for
Alzheimer Disease, Early OnsetMild Cognitive Impairment
University of Nebraska
Testing effectiveness (Phase 2)Study completedNCT02445794
What this trial is testing

A First in Human Study of RT001 in Patients With Friedreich's Ataxia

Who this might be right for
Friedreich's Ataxia
Biojiva LLC 19
Not applicableStudy completedNCT03049228
What this trial is testing

In and ex Vivo Mitochondrial Function of the Heart

Who this might be right for
Diabetes Mellitus, Type 2Diabetic Cardiomyopathies
Maastricht University Medical Center 38
Not applicableStudy completedNCT03227367
What this trial is testing

Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.

Who this might be right for
Periodontal DiseasePeriodontal Bone LossOsteoclastic Bone Loss
Meenakshi Ammal Dental College and Hospital 50
Early research (Phase 1)Study completedNCT02161380
What this trial is testing

Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Byron Lam 28
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