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Results for “Mitochondrial Myopathies”

131 trials

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Showing 20 of 131 results

Not applicableStudy completedNCT06784453
What this trial is testing

Evolution of Nutritional Status and Intestinal Function in Patients With MNGIE

Who this might be right for
Mitochondrial Neurogastrointestinal Encephalopathy Disease
IRCCS Azienda Ospedaliero-Universitaria di Bologna 8
Testing effectiveness (Phase 2)Ended earlyNCT02976038
What this trial is testing

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 28
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Testing effectiveness (Phase 2)Study completedNCT02805790
What this trial is testing

Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 30
Not applicableLooking for participantsNCT05653544
What this trial is testing

Natural History in Primary Mitochondrial Myopathies

Who this might be right for
Primary Mitochondrial Myopathies
Cristina Domínguez González 150
Testing effectiveness (Phase 2)Study completedNCT01642056
What this trial is testing

EPI-743 for Metabolism or Mitochondrial Disorders

Who this might be right for
Mitochondrial DiseaseNeurologyMyopathy
National Human Genome Research Institute (NHGRI) 20
Not applicableStudy completedNCT04678115
What this trial is testing

Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

Who this might be right for
BlepharoptosisPtosis, EyelidMyasthenia Gravis+3 more
Massachusetts Eye and Ear Infirmary 16
Post-approval studies (Phase 4)Study completedNCT01831934
What this trial is testing

Responses to Influenza Vaccine in Patients With Mitochondrial Disorders (MELAS)

Who this might be right for
MELAS Syndrome
Stanford University 22
Testing effectiveness (Phase 2)Temporarily pausedNCT04846036
What this trial is testing

The KHENERGYC Study

Who this might be right for
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMELAS+1 more
Khondrion BV 24
Not applicableStudy completedNCT03704311
What this trial is testing

Evaluation of Mitochondrial Function in Myofascial Trigger Points Cohort Pilot Study Using High-resolution Respirometry

Who this might be right for
Pain, NeckPain, BackMyofascial Trigger Point Pain+2 more
Medical University Innsbruck 20
Testing effectiveness (Phase 2)Study completedNCT01856868
What this trial is testing

Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)

Who this might be right for
Becker Muscular Dystrophy
Craig McDonald, MD 7
Not applicableWithdrawnNCT01872351
What this trial is testing

Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder

Who this might be right for
Chronic Fatigue Syndrome
Columbia University
Large-scale testing (Phase 3)Study completedNCT05162768
What this trial is testing

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)

Who this might be right for
Mitochondrial MyopathiesMitochondrial PathologyMitochondrial DNA Mutation+5 more
Stealth BioTherapeutics Inc. 102
Early research (Phase 1)Study completedNCT05063721
What this trial is testing

MABs Therapy m.3243A>G Mutation Carriers

Who this might be right for
Mitochondrial Myopathies
Maastricht University 6
Not applicableLooking for participantsNCT05346627
What this trial is testing

Home Based Personalized Training and Video Consultation in Mitochondrial Myopathies: Study of Efficacy and Tolerance.

Who this might be right for
Mitochondrial Myopathies
Centre Hospitalier Universitaire de Nice 15
Early research (Phase 1)Ended earlyNCT03862846
What this trial is testing

The Safety of REN001 in Patients With Primary Mitochondrial Myopathy

Who this might be right for
Primary Mitochondrial Myopathy
Reneo Pharma Ltd 23
Not applicableStudy completedNCT02490527
What this trial is testing

Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity

Who this might be right for
Statin Intolerance
University of California, San Diego 19
Not applicableLooking for participantsNCT04602325
What this trial is testing

Systemic Biomarkers of Brain Injury From Hyperammonemia

Who this might be right for
Urea Cycle DisorderOrganic AcidemiaMaple Syrup Urine Disease+3 more
Children's National Research Institute 24
Not applicableEnrolling By InvitationNCT07072676
What this trial is testing

The Use of Assistive Gait Devices Can Reduce the Risk of Falls in Patients With Neuromuscular Diseases Following a Training Period.

Who this might be right for
Inclusion Body MyositisMyotonic Dystrophy 1Myotonic Dystrophy 2+10 more
LMU Klinikum 30
Not applicableStudy completedNCT03973203
What this trial is testing

Niacin Supplementation in Healthy Controls and Mitochondrial Myopathy Patients

Who this might be right for
Mitochondrial Myopathies
University of Helsinki 15
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