Testing effectiveness (Phase 2)Study completedNCT02398201What this trial is testingBezafibrate in Mitochondrial MyopathyWho this might be right forMitochondrial Diseases Newcastle-upon-Tyne Hospitals NHS Trust 6
Not applicableStudy completedNCT00004770What this trial is testingPilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial MyopathyWho this might be right forMitochondrial Myopathy National Center for Research Resources (NCRR) 1
Not applicableStudy completedNCT02161848What this trial is testingMRI Study - Chronic Progressive External OphthalmoplegiaWho this might be right forChronic Progressive External Ophthalmoplegia Rigshospitalet, Denmark 133
Not applicableUnknownNCT02635269What this trial is testingFat and Sugar Metabolism During Exercise in Patients With Metabolic MyopathyWho this might be right forMetabolism, Inborn ErrorsLipid Metabolism, Inborn ErrorsCarbohydrate Metabolism, Inborn Errors+20 more Rigshospitalet, Denmark 60
Testing effectiveness (Phase 2)Study completedNCT02255422What this trial is testingRTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTORWho this might be right forMItochondrial Myopathies Biogen 53
Testing effectiveness (Phase 2)Ended earlyNCT04475549What this trial is testingPhase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)Who this might be right forMELAS Tisento Therapeutics 8
Not applicableLooking for participantsNCT02435940What this trial is testingInherited Retinal Degenerative Disease RegistryWho this might be right forEye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more Foundation Fighting Blindness 20,000
Not applicableUnknownNCT05199740What this trial is testingMtDNA Mutation Load Analysis in MesoangioblastsWho this might be right forMitochondrial Myopathies Maastricht University 30
Not applicableNot Yet RecruitingNCT07317401What this trial is testingInvestigating the Effects of Intermittent Hypoxia-Hyperoxia Treatment (IHHT) in People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) to Improve Fatigue, Pain, and Quality of Life by Targeting Mitochondrial Dysfunction and Autonomic Nervous System ImpairmentWho this might be right forMyalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3) University of Aarhus 104
Testing effectiveness (Phase 2)Study completedNCT02500628What this trial is testingHeart Rate Variability in Response to Metformin ChallengeWho this might be right forFibromyalgiaMitochondrial DiseasesMovement Disorders+1 more Woodinville Psychiatric Associates 61
Not applicableStudy completedNCT02375438What this trial is testingNutritional Assessment in Mitochondrial CytopathyWho this might be right forMitochondrial DiseasesMitochondrial MyopathiesMitochondrial Cytopathies Insel Gruppe AG, University Hospital Bern 26
Large-scale testing (Phase 3)Study completedNCT05162768What this trial is testingStudy to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)Who this might be right forMitochondrial MyopathiesMitochondrial PathologyMitochondrial DNA Mutation+5 more Stealth BioTherapeutics Inc. 102
Testing effectiveness (Phase 2)Study completedNCT06051448What this trial is testingPromoting Resilience in Stress Management (PRISM) and Clinical-focused Narrative (CFN) Pilot in Adults With Primary Mitochondrial Disease (PMD).Who this might be right forMitochondrial DiseasesMitochondrial MyopathiesMitochondrial Encephalomyopathies+2 more Children's Hospital of Philadelphia 16
Not applicableStudy completedNCT03704311What this trial is testingEvaluation of Mitochondrial Function in Myofascial Trigger Points Cohort Pilot Study Using High-resolution RespirometryWho this might be right forPain, NeckPain, BackMyofascial Trigger Point Pain+2 more Medical University Innsbruck 20
Testing effectiveness (Phase 2)Looking for participantsNCT06754098What this trial is testingDoxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) DeficiencyWho this might be right forThymidine Kinase 2 (TK2 ) DeficiencyMitochondrial Myopathies Cristina Domínguez González 15
Testing effectiveness (Phase 2)Study completedNCT01856868What this trial is testingUse of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)Who this might be right forBecker Muscular Dystrophy Craig McDonald, MD 7
Testing effectiveness (Phase 2)Study completedNCT04976140What this trial is testingAllogeneic Mitochondria (PN-101) Transplantation for Refractory Polymyositis or DermatomyositisWho this might be right forPolymyositisDermatomyositis Paean Biotechnology Inc. 9
Not applicableActive Not RecruitingNCT07558213What this trial is testingA Multi-Dimensional Model of cAre and transItion for Patients With cOmplex RAre DiseasesWho this might be right forRare DiseasesMitochondrial DiseasesMuscular Dystrophies+1 more Fondazione Policlinico Universitario Agostino Gemelli IRCCS 136
Not applicableLooking for participantsNCT05250375What this trial is testingNatural History Study of Mitochondrial MyopathyWho this might be right forPrimary Mitochondrial Disease Children's Hospital of Philadelphia 1,300
Early research (Phase 1)Study completedNCT03056209What this trial is testingSafety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male VolunteersWho this might be right forMELAS SyndromeMitochondrial Respiratory Chain Deficiencies Yungjin Pharm. Co., Ltd. 60