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Results for “Mixed Chimerism”

37 trials

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Showing 20 of 37 results

Testing effectiveness (Phase 2)Study completedNCT01780454
What this trial is testing

Renal Allograft Tolerance Through Mixed Chimerism

Who this might be right for
End Stage Renal Disease
Massachusetts General Hospital 2
Testing effectiveness (Phase 2)WithdrawnNCT03606746
What this trial is testing

Cellular Immunotherapy for Immune Tolerance in Past Recipients of HLA Zero-mismatch, Living Donor Kidney Transplants

Who this might be right for
Kidney Transplant Rejection
Medeor Therapeutics, Inc.
Testing effectiveness (Phase 2)Study completedNCT00004143
What this trial is testing

Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes

Who this might be right for
Sickle Cell AnemiaSevere Aplastic AnemiaParoxysmal Nocturnal Hemoglobinuria (PNH)+1 more
David Rizzieri, MD 2
Testing effectiveness (Phase 2)Study completedNCT00176865
What this trial is testing

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+3 more
Masonic Cancer Center, University of Minnesota 19
Early research (Phase 1)Study completedNCT00008450
What this trial is testing

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Who this might be right for
Adenosine Deaminase DeficiencyAutosomal Recessive DisorderImmune System Disorder+4 more
Fred Hutchinson Cancer Center 6
Not applicableStudy completedNCT00112593
What this trial is testing

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in Remission+176 more
Fred Hutchinson Cancer Center 5
Testing effectiveness (Phase 2)WithdrawnNCT01419704
What this trial is testing

Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies

Who this might be right for
Anemia, Sickle CellComplex and Transfusion-dependent HemoglobinopathiesThalassemia+4 more
Talaris Therapeutics Inc.
Testing effectiveness (Phase 2)Study completedNCT00004485
What this trial is testing

Bone Marrow Transplantation in Treating Children With Sickle Cell Disease

Who this might be right for
Sickle Cell Anemia
Fred Hutchinson Cancer Center 50
Early research (Phase 1)UnknownNCT00531635
What this trial is testing

Induction of Mixed Hemopoietic Chimerism in Patients Using Fludarabine, Low Dose TBI, PBSC Infusion and Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil

Who this might be right for
Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil
King Faisal Specialist Hospital & Research Center 350
Early research (Phase 1)Ended earlyNCT02370888
What this trial is testing

Lenalidomide After Allo-Hematopoietic Cell Transplant (HCT) in Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndromes (MDS) Subjects With Minimal Residual Disease

Who this might be right for
Leukemia, MyeloidMyelodysplastic Syndromes
University of Florida 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT00408447
What this trial is testing

Stem Cell Transplant in Sickle Cell Disease and Thalassemia

Who this might be right for
Sickle Cell DiseaseBeta Thalassemia
Columbia University 53
Not applicableStudy completedNCT05249452
What this trial is testing

Adding Azathioprine/Hydroxyurea Preconditioning to Alemtuzumab/TBI to Reduce Risk of Graft Failure in MSD HSCT in Adult SCD Patients

Who this might be right for
Sickle Cell Disease
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 20
Not applicableUnknownNCT04944511
What this trial is testing

PD-1 Antibody Improve Mixed Chimerism

Who this might be right for
PD-1 AntibodyMixed Chimerism
Beijing Friendship Hospital 20
Testing effectiveness (Phase 2)WithdrawnNCT03982992
What this trial is testing

Allogeneic Donor Lymphocyte Infusions Combined With Blinatumomab

Who this might be right for
B Cell Precursor Acute Lymphoblastic Leukemia With Mixed Chimerism or Minimal Residual Disease After Allogeneic Stem Cell TransplantationB-Cell Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia+2 more
Ludwig-Maximilians - University of Munich
Testing effectiveness (Phase 2)Study completedNCT00006251
What this trial is testing

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Who this might be right for
Acute Undifferentiated LeukemiaAdult Nasal Type Extranodal NK/T-cell LymphomaAnaplastic Large Cell Lymphoma+61 more
Fred Hutchinson Cancer Center 21
Very early researchLooking for participantsNCT06972069
What this trial is testing

Tolerance Through Mixed Chimerism (Sip-Tego)

Who this might be right for
Kidney FailureTransplant Recipient (Kidney)Transplant Tolerance+2 more
Tatsuo Kawai, MD, PhD 12
Early research (Phase 1)Study completedNCT02314403
What this trial is testing

Renal Allograft Tolerance Through Mixed Chimerism (Belatacept)

Who this might be right for
Kidney Failure, ChronicRenal Insufficiency
Massachusetts General Hospital 2
Testing effectiveness (Phase 2)Looking for participantsNCT07269041
What this trial is testing

Immune Tolerance Induction After Liver Transplantation

Who this might be right for
Liver TransplantationImmune ToleranceImmune Tolerance/Drug Effects+6 more
University of California, Los Angeles 12
Testing effectiveness (Phase 2)Study completedNCT00801632
What this trial is testing

Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection

Who this might be right for
Kidney TransplantationKidney Failure, Chronic
National Institute of Allergy and Infectious Diseases (NIAID) 5
Not applicableStudy completedNCT00427661
What this trial is testing

A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen

Who this might be right for
Sickle Cell DiseaseThalassemiaHemoglobinopathies
University of Pittsburgh 8
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