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Results for “Mixed Lineage Leukemia”

24 trials

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Showing 20 of 24 results

Large-scale testing (Phase 3)UnknownNCT03596892
What this trial is testing

Decitabine+BUCY vs BUCY Conditioning Regimen for MLL+ Acute Leukemia Undergoing Allo-HSCT

Who this might be right for
Allogeneic Hematopoietic Stem Cell TransplantationConditionsMixed-lineage-leukemia (MLL)-Rearranged Acute Leukemia
Nanfang Hospital, Southern Medical University 122
Testing effectiveness (Phase 2)Active Not RecruitingNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 45
Testing effectiveness (Phase 2)Study completedNCT02828358
What this trial is testing

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Who this might be right for
Acute Leukemia of Ambiguous LineageB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia
National Cancer Institute (NCI) 78
Testing effectiveness (Phase 2)Looking for participantsNCT06013423
What this trial is testing

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+7 more
Fred Hutchinson Cancer Center 54
Early research (Phase 1)Looking for participantsNCT04375631
What this trial is testing

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRecurrent Chronic Myelomonocytic LeukemiaRecurrent Myelodysplastic Syndrome+6 more
Fred Hutchinson Cancer Center 120
Not applicableStudy completedNCT04938115
What this trial is testing

Cell Therapy for CD7 Positive Acute Myeloid Leukemia or Mixed Lineage Leukemia

Who this might be right for
Leukemia, T Cell
Hebei Senlang Biotechnology Inc., Ltd. 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05761171
What this trial is testing

Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Who this might be right for
Recurrent Acute Leukemia of Ambiguous LineageRecurrent Acute Lymphoblastic LeukemiaRecurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage+9 more
Children's Oncology Group 78
Early research (Phase 1)Looking for participantsNCT05735184
What this trial is testing

Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Who this might be right for
Acute Myeloid LeukemiaMixed Lineage Leukemia Gene MutationRefractory AML+7 more
Kura Oncology, Inc. 420
Testing effectiveness (Phase 2)Study completedNCT02799147
What this trial is testing

GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia

Who this might be right for
Leukemia, Acute LymphoblasticAcute Myeloid LeukemiaMixed-Lineage Acute Leukemias
St. Petersburg State Pavlov Medical University 27
Early research (Phase 1)Active Not RecruitingNCT02091245
What this trial is testing

Phase I Trial of the Selective Inhibitor of Nuclear Export, KPT-330, in Relapsed Childhood ALL and AML

Who this might be right for
Relapsed Acute Lymphoblastic Leukemia (ALL)Refractory Acute Lymphoblastic Leukemia (ALL)Relapsed Acute Myelogenous Leukemia (AML)+6 more
Dana-Farber Cancer Institute 16
Early research (Phase 1)Study completedNCT00889408
What this trial is testing

DT2219ARL for Relapsed or Refractory CD19 (+), CD 22 (+) B-Lineage Leukemia Or Lymphoma

Who this might be right for
LeukemiaLymphoma
Masonic Cancer Center, University of Minnesota 25
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07819396
What this trial is testing

Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+11 more
Fred Hutchinson Cancer Center 52
Early research (Phase 1)UnknownNCT00004858
What this trial is testing

Monoclonal Antibody Therapy in Treating Patients With Recurrent Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma

Who this might be right for
LeukemiaLymphoma
Parker Hughes Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02135874
What this trial is testing

Clofarabine, Idarubicin, Cytarabine, Vincristine Sulfate, and Dexamethasone in Treating Patients With Newly Diagnosed or Relapsed Mixed Phenotype Acute Leukemia

Who this might be right for
Acute Bilineal LeukemiaAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+5 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Looking for participantsNCT04988555
What this trial is testing

Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

Who this might be right for
Leukemia, Myeloid, AcuteLeukemia, Lymphocytic, AcuteMultiple Myeloma+1 more
Sumitomo Pharma America, Inc. 606
Testing effectiveness (Phase 2)Looking for participantsNCT04065399
What this trial is testing

Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMixed Lineage Acute Leukemia+2 more
Syndax Pharmaceuticals 447
Testing effectiveness (Phase 2)Active Not RecruitingNCT04067336
What this trial is testing

First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Advanced Malignant NeoplasmAcute Myeloid LeukemiaMixed Lineage Leukemia+4 more
Kura Oncology, Inc. 263
Testing effectiveness (Phase 2)Ended earlyNCT02419755
What this trial is testing

Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies

Who this might be right for
Mixed Lineage Acute LeukemiaAcute Myeloid LeukemiaAcute Lymphoid Leukemia
St. Jude Children's Research Hospital 12
Testing effectiveness (Phase 2)Ended earlyNCT00866281
What this trial is testing

The Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic Leukemia
Novartis Pharmaceuticals 22
Early research (Phase 1)Study completedNCT01684150
What this trial is testing

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Epizyme, Inc. 51
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