Post-approval studies (Phase 4)UnknownNCT04521452What this trial is testingRandomized, Open-label Trial of Inhibitory Effect of Evogliptin on Progression of CAVDWho this might be right forCAVD Asan Medical Center 218
Not applicableActive Not RecruitingNCT05149755What this trial is testingEvolut™ EXPAND TAVR II Pivotal TrialWho this might be right forModerate Aortic Valve Stenosis Medtronic Cardiovascular 650
Not applicableLooking for participantsNCT05851209What this trial is testingMechanisms Of Disease Progression in Aortic Stenosis - the MODAS StudyWho this might be right forAortic StenosisImagingPathogenesis+3 more Heinrich-Heine University, Duesseldorf 938
Not applicableEnrolling By InvitationNCT07827105What this trial is testingECG-based AI Screening for Cases of Undiagnosed Moderate-to-Severe Aortic Stenosis in the Primary Care SettingWho this might be right forAortic Stenosis AccurKardia, Inc. 4,000
Not applicableLooking for participantsNCT06168123What this trial is testingFuture Optimal Research and Care Evaluation - Aortic StenosisWho this might be right forSevere Aortic Valve StenosisModerate Aortic Valve Stenosis St. Antonius Hospital 800
Testing effectiveness (Phase 2)Ended earlyNCT02862600What this trial is testingOpen-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart FailureWho this might be right forCardiomyopathy, HypertrophicCardiomyopathy, Hypertrophic, Familial Heart Metabolics Limited 35
Early research (Phase 1)Study completedNCT02049203What this trial is testingSafety of Ataciguat in Patients With Moderate Calcific Aortic Valve StenosisWho this might be right forAortic Valve Stenosis Jordan D. Miller, Ph.D. 44
Not applicableUnknownNCT01575249What this trial is testingIdentification of Parameters in rapId-proGression Subgroup Patients With Moderate Aortic StenosisWho this might be right forAortic Stenosis Carol Davila University of Medicine and Pharmacy 200
Large-scale testing (Phase 3)WithdrawnNCT02431221What this trial is testingEfficacy, Safety, and Tolerability of Perhexiline in Subjects With Hypertrophic Cardiomyopathy and Heart FailureWho this might be right forHypertrophic Cardiomyopathy Heart Metabolics Limited
Not applicableNot Yet RecruitingNCT07532317What this trial is testingComparison of Myval THV Series With Guideline-Directed Medical Therapy in Participants With Moderate Aortic StenosisWho this might be right forModerate Aortic Stenosis Meril Life Sciences Pvt. Ltd. 778
Not applicableWithdrawnNCT07060183What this trial is testingAortic Valve Replacement for Moderate Aortic Stenosis With Left Ventricular Decompensation Early Feasibility StudyWho this might be right forModerate Aortic Valve Stenosis Dermed Diagnostics, Inc.
Testing effectiveness (Phase 2)Study completedNCT02481258What this trial is testingA Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve CalcificationWho this might be right forAortic Valve Stenosis Mayo Clinic 35
Not applicableNot Yet RecruitingNCT07690748What this trial is testingRemote Monitoring for Patients With Aortic StenosisWho this might be right forAortic Stenosis Baker Heart and Diabetes Institute 160
Not applicableLooking for participantsNCT06595992What this trial is testingProspective Observational Cohort Study of Moderate Aortic Valve DiseaseWho this might be right forModerate Aortic Valve StenosisModerate Aortic Valve RegurgitationAortic Valve Disease Second Affiliated Hospital, Zhejiang University, School of Medicine 1,000
Large-scale testing (Phase 3)Study completedNCT06469645What this trial is testingThe Role of SGLT2i in Management of Moderate ASWho this might be right forModerate Aortic Valve Stenosis University of East Anglia 104
Not applicableNot Yet RecruitingNCT07828730What this trial is testingSparrow App Guided Evaluation (SAGE) Vanguard Trial for Aortic Stenosis in Adults Aged Seventy and OlderWho this might be right forModerate or Severe Aortic Stenosis Sunnybrook Health Sciences Centre 1,000
Large-scale testing (Phase 3)Looking for participantsNCT07001800What this trial is testingAtaciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled StudyWho this might be right forModerate Aortic Valve Stenosis Kardigan, Inc. 1,276
Large-scale testing (Phase 3)Ended earlyNCT05143177What this trial is testingEvaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS)Who this might be right forCalcific Aortic Valve Disease REDNVIA Co., Ltd. 486
Not applicableLooking for participantsNCT04889872What this trial is testingPROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVRWho this might be right forAortic Stenosis, CalcificAortic Valve Stenosis Edwards Lifesciences 2,250
Not applicableLooking for participantsNCT05310461What this trial is testingEarly Versus Deferred Aortic Valve Replacement in Patients With Moderate Aortic Stenosis and Mitral RegurgitationWho this might be right forAortic Valve Replacement in Patients With Moderate Aortic Stenosis Combined With Mitral Regurgitation Insel Gruppe AG, University Hospital Bern 80