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Results for “Moderate Hepatic Dysfunction”

26 trials

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Showing 20 of 26 results

Early research (Phase 1)Study completedNCT06916078
What this trial is testing

Lepodisiran (LY3819469) in Participants With Normal, Mild, Moderate, or Severe Liver Function

Who this might be right for
Liver DysfunctionHealthy
Eli Lilly and Company 30
Early research (Phase 1)Study completedNCT00118170
What this trial is testing

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Adult Burkitt Lymphoma+42 more
National Cancer Institute (NCI) 150
Early research (Phase 1)Ended earlyNCT05126329
What this trial is testing

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 13
Early research (Phase 1)Looking for participantsNCT07600788
What this trial is testing

A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function.

Who this might be right for
Chronic Hepatitis B
Ausper Biopharma Co., Ltd. 32
Early research (Phase 1)Study completedNCT06908954
What this trial is testing

The Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose

Who this might be right for
Hepatic ImpairmentHealthy
Ipsen 31
Early research (Phase 1)Study completedNCT00416702
What this trial is testing

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Who this might be right for
Hepatic Insufficiency
Novartis 32
Early research (Phase 1)Study completedNCT00025415
What this trial is testing

Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Undifferentiated LeukemiaAIDS-related Peripheral/Systemic Lymphoma+78 more
National Cancer Institute (NCI) 60
Post-approval studies (Phase 4)Study completedNCT04349696
What this trial is testing

Pharmacokinetic and Pharmacodynamic Study of Glufast Tablets 10mg(Mitiglinide)

Who this might be right for
Type 2 Diabetes MellitusLiver Dysfunction
Orient Europharma Co., Ltd. 16
Early research (Phase 1)Study completedNCT01571388
What this trial is testing

Compare Pharmacokinetics Of Dacomitinib (PF-00299804) Between Healthy Subjects And Subjects With Mild And Moderate Hepatic Impairment

Who this might be right for
HealthyOtherwise Healthy Volunteers With Mild or Moderate Hepatic Dysfunction
Pfizer 25
Early research (Phase 1)Study completedNCT05718258
What this trial is testing

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 26
Early research (Phase 1)Study completedNCT00791284
What this trial is testing

The Pharmacokinetics of Paliperidone in Volunteers With Normal or Impaired Liver Function

Who this might be right for
SchizophreniaHepatic Impairment
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 20
Not applicableActive Not RecruitingNCT01047735
What this trial is testing

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes

Who this might be right for
Type 2 Diabetes MellitusObesity
University of Pittsburgh 69
Early research (Phase 1)UnknownNCT06176716
What this trial is testing

Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride

Who this might be right for
Hepatic Insufficiency
Ahon Pharmaceutical Co., Ltd. 24
Early research (Phase 1)Study completedNCT06444204
What this trial is testing

Evaluate the Effect of Mild and Moderate Hepatic Impairment on the Single-Dose Pharmacokinetics of Rilzabrutinib (PRN1008)

Who this might be right for
Hepatic Function AbnormalHealthy Volunteers
Principia Biopharma, a Sanofi Company 29
Early research (Phase 1)Study completedNCT00437424
What this trial is testing

Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction

Who this might be right for
Carcinoma, Hepatocellular
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT00047346
What this trial is testing

Erlotinib in Treating Patients With Unresectable Liver Cancer and Liver Dysfunction

Who this might be right for
Adult Primary Hepatocellular CarcinomaAdvanced Adult Primary Liver CancerLocalized Unresectable Adult Primary Liver Cancer+1 more
National Cancer Institute (NCI) 24
Early research (Phase 1)Study completedNCT05607173
What this trial is testing

A Pharmacokinetic and Tolerability Study of Fexinidazole in a Single Oral Dose in Adult Participants With Mild and Moderate Hepatic Impairment

Who this might be right for
Hepatic Function Abnormal
Sanofi 21
Early research (Phase 1)Study completedNCT00608361
What this trial is testing

Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery

Who this might be right for
Adult Acute Lymphoblastic Leukemia in RemissionAdult B Acute Lymphoblastic LeukemiaAdult Hepatocellular Carcinoma+82 more
National Cancer Institute (NCI) 80
Early research (Phase 1)Study completedNCT00499811
What this trial is testing

Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction

Who this might be right for
Adult Grade III Lymphomatoid GranulomatosisAdult Nasal Type Extranodal NK/T-cell LymphomaAnaplastic Large Cell Lymphoma+60 more
National Cancer Institute (NCI) 15
Early research (Phase 1)Study completedNCT02604498
What this trial is testing

Pharmacokinetics Study of Nemonoxacin Malate Capsules in Subjects With Moderate Impaired Hepatic Function

Who this might be right for
Liver Dysfunction
Zhejiang Medicine Co., Ltd. 20
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