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Results for “Moderate Liver Impairment”

98 trials

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Showing 20 of 98 results

Early research (Phase 1)Study completedNCT03681457
What this trial is testing

Evaluation of the Pharmacokinetics of Tropifexor in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Healthy Control Subjects

Who this might be right for
Non-alcoholic Fatty Liver Disease
Novartis Pharmaceuticals 42
Early research (Phase 1)Study completedNCT05116826
What this trial is testing

Nitazoxanide Pharmacokinetic Parameters in Hepatic Impaired Patients

Who this might be right for
Moderate Hepatic ImpairmentSevere Hepatic ImpairmentLiver Diseases
Genfit 25
Early research (Phase 1)Study completedNCT05419635
What this trial is testing

Learn How the Study Treatment Asundexian Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body in Participants With Mild or Moderate Reduction of Liver Function Compared to Participants With Normal Liver Function

Who this might be right for
Prevention of Thromboembolic EventsAtrial FibrillationAcute Myocardial Infarction+2 more
Bayer 27
Early research (Phase 1)Study completedNCT04634149
What this trial is testing

Evaluate the Drug Levels, Safety, and Tolerability of BMS-986036 in Participants With Normal Liver Function and Participants With Moderate and Severe Liver Impairment

Who this might be right for
Moderate Liver ImpairmentSevere Liver Impairment
Bristol-Myers Squibb 16
Early research (Phase 1)Study completedNCT04406896
What this trial is testing

The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics

Who this might be right for
Healthy SubjectsHepatic Impairment
Viatris Innovation GmbH 24
Early research (Phase 1)Looking for participantsNCT07168356
What this trial is testing

Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease

Who this might be right for
Hepatitis B
GlaxoSmithKline 32
Early research (Phase 1)Ended earlyNCT03295266
What this trial is testing

Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006)

Who this might be right for
Hepatic InsufficiencyAntibacterial Agents
Merck Sharp & Dohme LLC 9
Early research (Phase 1)Study completedNCT00698464
What this trial is testing

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Who this might be right for
Hepatic CirrhosisAlcoholism
Novartis Pharmaceuticals 34
Early research (Phase 1)Study completedNCT06340347
What this trial is testing

Learn How the Body Processes the Study Medicine Called Osivelotor (PF-07940367) in People With Loss of Liver Function

Who this might be right for
Liver Diseases
Pfizer 8
Early research (Phase 1)Not Yet RecruitingNCT05093972
What this trial is testing

Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)

Who this might be right for
Hepatic Insufficiency
Merck Sharp & Dohme LLC 22
Early research (Phase 1)Study completedNCT00851227
What this trial is testing

Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function

Who this might be right for
Liver DiseaseHyponatremia
Cumberland Pharmaceuticals 26
Early research (Phase 1)UnknownNCT05151705
What this trial is testing

A Trial of HR17031 Injection With Hepatic Insufficiency

Who this might be right for
Improved Glycemic Control in Patients With Type 2 Diabetes
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT02581592
What this trial is testing

Pharmacokinetics of TD-4208 in Patients With Moderate Hepatic Impairment

Who this might be right for
Hepatic Impairment
Mylan Inc. 16
Early research (Phase 1)Study completedNCT00416702
What this trial is testing

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Who this might be right for
Hepatic Insufficiency
Novartis 32
Early research (Phase 1)Study completedNCT04867941
What this trial is testing

Evaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196

Who this might be right for
Hepatic Insufficiency
Acerta Pharma BV 18
Early research (Phase 1)Study completedNCT05731908
What this trial is testing

Test How BI 690517 is Taken up in the Body of People With and Without Liver Problems

Who this might be right for
Liver DiseasesHealthy
Boehringer Ingelheim 28
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Testing effectiveness (Phase 2)Study completedNCT01830127
What this trial is testing

BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3

Who this might be right for
Hepatitis C, Chronic
Boehringer Ingelheim 35
Early research (Phase 1)Study completedNCT03341884
What this trial is testing

Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants

Who this might be right for
Hepatic Insufficiency
Genentech, Inc. 29
Early research (Phase 1)Study completedNCT06812780
What this trial is testing

Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD2389

Who this might be right for
Hepatic Impairment
AstraZeneca 35
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