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Results for “Moderate and Severe Active Rheumatoid Arthritis”

147 trials

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Showing 20 of 147 results

Testing effectiveness (Phase 2)Study completedNCT00243412
What this trial is testing

The Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate

Who this might be right for
Rheumatoid Arthritis
Genentech, Inc. 42
Large-scale testing (Phase 3)Ended earlyNCT01682512
What this trial is testing

Efficacy, Pharmacokinetics, and Safety of BI 695500 in Patients With Rheumatoid Arthritis

Who this might be right for
Arthritis, Rheumatoid
Boehringer Ingelheim 294
Testing effectiveness (Phase 2)Study completedNCT06800157
What this trial is testing

Study of LW402 Tablets in Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Arthritis, Rheumatoid
Shanghai Longwood Biopharmaceuticals Co., Ltd. 72
Testing effectiveness (Phase 2)Study completedNCT03813199
What this trial is testing

Study of Two Doses of ABX464 in Participants With Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Abivax S.A. 60
Post-approval studies (Phase 4)Ended earlyNCT01283971
What this trial is testing

RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 96
Testing effectiveness (Phase 2)Study completedNCT07335952
What this trial is testing

Proximod, a Selective Sphingosine-1-phosphate Receptor 1 Modulator in Patients With Moderate-to-severe Active Rheumatoid Arthritis: a Double-blind, Randomised, Placebo-controlled, Phase 2 Trial.

Who this might be right for
Rheumatoid Arthritis
Peking University People's Hospital 179
Testing effectiveness (Phase 2)Study completedNCT01894516
What this trial is testing

Dose-finding Study of GLPG0634 as Monotherapy in Active Rheumatoid Arthritis (RA) Participants (DARWIN2)

Who this might be right for
Rheumatoid Arthritis
Galapagos NV 287
Large-scale testing (Phase 3)Study completedNCT03357471
What this trial is testing

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease

Who this might be right for
Moderate and Severe Active Rheumatoid ArthritisActive Psoriatic ArthritisActive Ankylosing Spondylitis+1 more
UCB Biopharma S.P.R.L. 70
Large-scale testing (Phase 3)Study completedNCT02955212
What this trial is testing

A Study With Upadacitinib (ABT-494) in Subjects From China and Selected Countries With Moderately to Severely Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Conventional Synthetic Disease-Modifying Anti-Rheumatic Drugs (csDMARDs)

Who this might be right for
Rheumatoid Arthritis (RA)
AbbVie 338
Large-scale testing (Phase 3)Active Not RecruitingNCT06245408
What this trial is testing

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Who this might be right for
Sjögren's Syndrome (SS)
Amgen 434
Testing effectiveness (Phase 2)Active Not RecruitingNCT07100938
What this trial is testing

A Study Investigating the Efficacy and Safety of BGB-45035 Versus Placebo in Adults With Moderate to Severe Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
BeiGene 49
Testing effectiveness (Phase 2)Study completedNCT04413617
What this trial is testing

TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE

Who this might be right for
Rheumatoid Arthritis
Pfizer 460
Testing effectiveness (Phase 2)Ended earlyNCT04888585
What this trial is testing

Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Who this might be right for
Rheumatoid Arthritis (RA)
AbbVie 473
Early research (Phase 1)Study completedNCT05232396
What this trial is testing

Clinical Study of Single Dose IL-6R mAb Injection in RA Patients

Who this might be right for
Rheumatoid Arthritis
Beijing VDJBio Co., LTD. 40
Testing effectiveness (Phase 2)Study completedNCT02504671
What this trial is testing

Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 222
Not applicableStudy completedNCT05572567
What this trial is testing

Study to Evaluate Safety and Effects of Tofacitinib and Biologic Disease Modifying Antirheumatic Drugs in People Treated for Rheumatoid Arthritis

Who this might be right for
Arthritis, Rheumatoid
Pfizer 1,972
Large-scale testing (Phase 3)Study completedNCT02760407
What this trial is testing

Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo and Adalimumab, in Subjects With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Have Active Disease

Who this might be right for
Rheumatoid Arthritis
R-Pharm International, LLC 1,648
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07423533
What this trial is testing

Phase IIb Clinical Study to Assess the Efficacy and Safety of GenSci120 Injection in Patients With Moderately to Severely Active RA Who Have an Inadequate Response to at Least One DMARD

Who this might be right for
Rheumatoid Arthritis
Changchun GeneScience Pharmaceutical Co., Ltd. 450
Large-scale testing (Phase 3)Study completedNCT02886728
What this trial is testing

Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy

Who this might be right for
Rheumatoid Arthritis
Gilead Sciences 1,252
Not applicableStudy completedNCT01362062
What this trial is testing

Study to Evaluate the Safety, Tolerability and Efficacy of Tocilizumab in Participants With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Non-Biologic Disease Modifying Anti-rheumatic Drugs (DMARDs) and/or Anti-tumor Necrosis Factor (Anti-TNF) Therapy

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 110
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