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Results for “Moderate to Severe Functional Impairments”

62 trials

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Showing 20 of 62 results

Early research (Phase 1)Study completedNCT01374113
What this trial is testing

Safinamide Renal Impairment Trial

Who this might be right for
Renal Impairment
Newron Pharmaceuticals SPA 24
Early research (Phase 1)Study completedNCT00750620
What this trial is testing

A Pharmacokinetic Study of YM178 in Normal Subjects and Those With Mild, Moderate, and Severe Renal Impairment

Who this might be right for
Renal Impairment
Astellas Pharma Inc 33
Early research (Phase 1)Study completedNCT01185873
What this trial is testing

Danoprevir in Healthy Volunteers And Patients With Hepatic Impairment

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 81
Not applicableStudy completedNCT01000168
What this trial is testing

Treadmill Therapy and Brain Injuries

Who this might be right for
Cerebral StrokeHemiplegiaModerate to Severe Functional Impairments
Sunnaas Rehabilitation Hospital 60
Early research (Phase 1)Study completedNCT05718843
What this trial is testing

Test How Iclepertin is Taken up in the Blood of People With and Without Kidney Problems

Who this might be right for
Renal Insufficiency
Boehringer Ingelheim 36
Early research (Phase 1)Study completedNCT02096718
What this trial is testing

Afatinib in Subjects With Kidney Dysfunction

Who this might be right for
Renal Insufficiency
Boehringer Ingelheim 30
Early research (Phase 1)Study completedNCT04552808
What this trial is testing

To Evaluate the Pharmacokinetics and Safety of Yimitasvir Phosphate Capsules in Subjects With Moderate and Severe Liver Function Impairment and in Healthy Subjects

Who this might be right for
Hepatic Impairment
Sunshine Lake Pharma Co., Ltd. 16
Early research (Phase 1)Study completedNCT02397707
What this trial is testing

Pharmacokinetics of Voxilaprevir in Adults With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Who this might be right for
HCV Infection
Gilead Sciences 33
Not applicableStudy completedNCT05912933
What this trial is testing

Learn About the Relationship Between Hepatic Impairment and Myelosuppression (Decreased Bone Marrow Function) in Breast Cancer Patients Treated With the Study Medicine Palbociclib (Pal-bow-sai-klib)

Who this might be right for
Breast Cancer
Pfizer 1,342
Early research (Phase 1)Ended earlyNCT02050815
What this trial is testing

MEK162 in Healthy Subjects With Normal Hepatic Function and Subjects With Impaired Hepatic Function

Who this might be right for
Hepatic Impairment
Array Biopharma, now a wholly owned subsidiary of Pfizer 27
Testing effectiveness (Phase 2)Study completedNCT01082640
What this trial is testing

Effect of Febuxostat on Renal Function in Patients With Gout and Moderate to Severe Renal Impairment

Who this might be right for
Renal Impairment
Takeda 96
Early research (Phase 1)Ended earlyNCT04678505
What this trial is testing

Study of a Single Intravenous (IV) Dose of MK-3402 in Participants With Impaired Renal Function and in Healthy Controls (MK-3402-004)

Who this might be right for
Renal Impairment
Merck Sharp & Dohme LLC 9
Testing effectiveness (Phase 2)Looking for participantsNCT05790239
What this trial is testing

MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder

Who this might be right for
Post Traumatic Stress Disorder
Stephen Robert Marder 40
Early research (Phase 1)Study completedNCT03890809
What this trial is testing

An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage

Who this might be right for
Liver DysfunctionHealthy Volunteers
Bristol-Myers Squibb 32
Early research (Phase 1)Study completedNCT00999336
What this trial is testing

Determine the Pharmacokinetics, Pharmacodynamics, and Tolerabiltiy of Betrixaban in Patients With Mild, Moderate, and Severe Renal Impairment

Who this might be right for
Renal Impairment
Portola Pharmaceuticals 32
Early research (Phase 1)Study completedNCT03196206
What this trial is testing

Evaluate Pharmacokinetics and Safety of BMS-986177 in Participants With Normal Renal Function and With Moderate or Severe Renal Impairment

Who this might be right for
Thrombosis
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT01764776
What this trial is testing

Effect of Hepatic Impairment on LDE225..

Who this might be right for
Normal Hepatic FunctionImpaired Hepatic Function
Novartis Pharmaceuticals 33
Early research (Phase 1)Study completedNCT06352411
What this trial is testing

Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems

Who this might be right for
HealthyRenal Impairment
Boehringer Ingelheim 42
Early research (Phase 1)Study completedNCT05835180
What this trial is testing

A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Who this might be right for
Non-alcoholic SteatohepatitisHepatic ImpairmentCirrhosis
Sagimet Biosciences Inc. 48
Early research (Phase 1)Study completedNCT04176536
What this trial is testing

A Study in People With Normal Kidney Function and People With Reduced Kidney Function to Test How BI 764198 is Processed in the Body

Who this might be right for
HealthyChronic Kidney Disease
Boehringer Ingelheim 28
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