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Results for “Moderate to Severe Opioid-use Disorder”

18 trials

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Showing 18 of 18 results

Post-approval studies (Phase 4)UnknownNCT05594121
What this trial is testing

Monthly Versus Daily Buprenorphine Formulations for Treatment of Opiate Use Disorder

Who this might be right for
Moderate to Severe Opioid Use Disorder
Royal Victoria Hospital, Canada 90
Testing effectiveness (Phase 2)Study completedNCT02611752
What this trial is testing

A Multiple Dose Opioid Challenge Study

Who this might be right for
Moderate or Severe Opioid Use Disorder
Braeburn Pharmaceuticals 47
Testing effectiveness (Phase 2)Looking for participantsNCT06651177
What this trial is testing

Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

Who this might be right for
Opioid Use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
T. John Winhusen, PhD 310
Not applicableActive Not RecruitingNCT04921787
What this trial is testing

EXHIT ENTRE Implementation Trial of High Intensity Versus Low Intensity Strategy

Who this might be right for
Substance Use DisordersOpioid Use Disorder, SevereOpioid Use Disorder, Moderate
Gavin Bart 24
Testing effectiveness (Phase 2)Looking for participantsNCT05529927
What this trial is testing

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Who this might be right for
Cocaine Use Disorder
Parnassia Addiction Research Centre 204
Testing effectiveness (Phase 2)Study completedNCT03389750
What this trial is testing

Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.

Who this might be right for
Opioid Use Disorder
New York State Psychiatric Institute 16
Early research (Phase 1)Ended earlyNCT06406400
What this trial is testing

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Who this might be right for
Opioid Use Disorder
AstraZeneca 15
Large-scale testing (Phase 3)Study completedNCT03661996
What this trial is testing

An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA

Who this might be right for
Knee Osteoarthritis
Centrexion Therapeutics 854
Not applicableLooking for participantsNCT07780097
What this trial is testing

TRTME: Improving Outpatient Initiation of Medication for Opioid Use Disorder Following Hospitalization

Who this might be right for
Opioid Use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
T. John Winhusen, PhD 30
Large-scale testing (Phase 3)Study completedNCT04345718
What this trial is testing

EXHIT ENTRE Comparative Effectiveness Trial

Who this might be right for
Substance Use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
Gavin Bart 344
Not applicableLooking for participantsNCT07631598
What this trial is testing

Buprenorphine Implementation at Syringe Service Programs to Reduce Overdoses

Who this might be right for
Opioid Use DisorderOpioid Use Disorder, SevereOpioid Use Disorder, Moderate
Montefiore Medical Center 512
Post-approval studies (Phase 4)WithdrawnNCT03529331
What this trial is testing

A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED

Who this might be right for
Pain
Antonios Likourezos
Not applicableNot Yet RecruitingNCT07451197
What this trial is testing

Family-Focused Study to Support Medication for Opioid Use Disorder

Who this might be right for
Opioid Use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
University of Wisconsin, Madison 338
Not applicableStudy completedNCT05063227
What this trial is testing

Prediction of Postoperative Pain by Nociception Monitoring

Who this might be right for
Pain, PostoperativeAnalgesiaAnesthesia Recovery Period+1 more
Universitätsklinikum Hamburg-Eppendorf 60
Post-approval studies (Phase 4)Study completedNCT04995029
What this trial is testing

Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users

Who this might be right for
Moderate to Severe Opioid-use Disorder
Indivior Inc. 785
Testing effectiveness (Phase 2)Study completedNCT06576843
What this trial is testing

INDV-6001 Multiple-Dose Pharmacokinetic Study

Who this might be right for
Moderate to Severe Opioid Use Disorder
Indivior Inc. 123
Not applicableStudy completedNCT04982627
What this trial is testing

A Brief Negotiation Interview Chatbot to Improve Buprenorphine Engagement Among Justice-Involved Individuals

Who this might be right for
Opioid Use Disorder, ModerateOpioid Use Disorder, SevereCriminal Behavior
Center for Progressive Recovery, LLC 4
Testing effectiveness (Phase 2)Study completedNCT06384157
What this trial is testing

Proof of Concept and Dose-ranging Study of INDV-2000 in Individuals With Moderate to Severe Opioid Use Disorder

Who this might be right for
Opioid Use Disorder
Indivior Inc. 300