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Results for “Moderate-to-severe Pruritus”

64 trials

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Showing 20 of 64 results

Early research (Phase 1)UnknownNCT04317209
What this trial is testing

SHR0410 in Hemodialysis Patients With Pruritus

Who this might be right for
Pruritus
Jiangsu HengRui Medicine Co., Ltd. 54
Large-scale testing (Phase 3)Study completedNCT02210689
What this trial is testing

A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women

Who this might be right for
BACTERIAL VAGINOSISSigns and Symptoms to be Evaluated and Recorded IncludeVaginal Discharge Color, Odor, and Consistency+2 more
Actavis Inc. 604
Large-scale testing (Phase 3)Study completedNCT03281538
What this trial is testing

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Who this might be right for
Uremic Pruritus
Cara Therapeutics, Inc. 288
Post-approval studies (Phase 4)Looking for participantsNCT05042258
What this trial is testing

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

Who this might be right for
Atopic DermatitisSleep Disturbance
Northwestern University 40
Testing effectiveness (Phase 2)Study completedNCT04018027
What this trial is testing

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

Who this might be right for
PruritusAtopic Dermatitis
Cara Therapeutics, Inc. 401
Testing effectiveness (Phase 2)Study completedNCT04706975
What this trial is testing

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)

Who this might be right for
PruritusNotalgia Paresthetica
Cara Therapeutics, Inc. 126
Large-scale testing (Phase 3)Study completedNCT01815424
What this trial is testing

A Study Evaluating The Efficacy And Safety Of CP-690,550 In Asian Subjects With Moderate To Severe Plaque Psoriasis

Who this might be right for
Psoriasis
Pfizer 266
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06733519
What this trial is testing

TH104 for the Treatment of Pruritus in Primary Biliary Cholangitis

Who this might be right for
PruritusPrimary Biliary Cholangitis
Tharimmune Inc 40
Large-scale testing (Phase 3)Looking for participantsNCT06446310
What this trial is testing

Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritus

Who this might be right for
Uremic Pruritus
Qilu Pharmaceutical (Hainan) Co., Ltd. 194
Large-scale testing (Phase 3)Ended earlyNCT05356403
What this trial is testing

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Who this might be right for
Chronic Kidney DiseasesPruritus
Cara Therapeutics, Inc. 105
Large-scale testing (Phase 3)Study completedNCT03668613
What this trial is testing

Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis

Who this might be right for
Moderate to Severe Chronic Plaque-type Psoriasis
Novartis Pharmaceuticals 84
Testing effectiveness (Phase 2)Ended earlyNCT04605094
What this trial is testing

Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
AstraZeneca 194
Large-scale testing (Phase 3)Ended earlyNCT05342623
What this trial is testing

Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Who this might be right for
Chronic Kidney DiseasesPruritus
Cara Therapeutics, Inc. 286
Post-approval studies (Phase 4)Study completedNCT05590585
What this trial is testing

Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial

Who this might be right for
Moderate-to-Severe Atopic DermatitisAtopic Eczema
Regeneron Pharmaceuticals 124
Large-scale testing (Phase 3)Study completedNCT02601703
What this trial is testing

To Study Generic Tacrolimus Ointment, 0.1% in the Treatment of Moderate to Severe Atopic Dermatitis (Inflammation of Skin: Itchy, Red, Swollen, and Cracked Skin)

Who this might be right for
Atopic Dermatitis
Glenmark Pharmaceuticals Ltd. India 1,110
Large-scale testing (Phase 3)Study completedNCT03422653
What this trial is testing

Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Who this might be right for
Uremic Pruritus
Cara Therapeutics, Inc. 378
Testing effectiveness (Phase 2)Looking for participantsNCT06593392
What this trial is testing

Safety and Tolerability of Difelikefalin in Adolescents on Haemodialysis With Moderate-to-Severe Pruritus

Who this might be right for
PruritusChronic Kidney Diseases
Vifor Fresenius Medical Care Renal Pharma 18
Large-scale testing (Phase 3)Study completedNCT03066609
What this trial is testing

Study of Efficacy and Safety of Secukinumab in Subjects With Moderate to Severe Chronic Plaque-type Psoriasis

Who this might be right for
Plaque Psoriasis
Novartis Pharmaceuticals 543
Testing effectiveness (Phase 2)Study completedNCT03100344
What this trial is testing

Dose-ranging Study of Nemolizumab in Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
Galderma R&D 226
Post-approval studies (Phase 4)Study completedNCT03440736
What this trial is testing

Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome

Who this might be right for
PsoriasisMetabolic Syndrome
Novartis Pharmaceuticals 781
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