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Results for “Moderate-to-severe Pruritus”

65 trials

Showing 20 of 65 results

Post-approval studies (Phase 4)Study completedNCT02767271
What this trial is testing

Maximal Use of Luliconazole Cream 1% in Pediatric Participants With Moderate to Severe Tinea Pedis or Tinea Cruris

Who this might be right for
Tinea PedisTinea Cruris
Bausch Health Americas, Inc. 30
Testing effectiveness (Phase 2)Study completedNCT03617536
What this trial is testing

Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Who this might be right for
Chronic Kidney DiseasesPruritus
Cara Therapeutics, Inc. 269
Large-scale testing (Phase 3)Study completedNCT02858726
What this trial is testing

Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Who this might be right for
Uremic Pruritus
Cara Therapeutics, Inc. 226
Large-scale testing (Phase 3)Study completedNCT05075408
What this trial is testing

To Evaluate the Efficacy and Safety of Nemolizumab for 12 Weeks in Participants With Chronic Kidney Disease With Associated Moderate to Severe Pruritus

Who this might be right for
Chronic Kidney Disease Associated Moderate to Severe Pruritus
Galderma R&D 258
Large-scale testing (Phase 3)Study completedNCT03504852
What this trial is testing

Efficacy and Safety of 2 Secukinumab Regimens in 90kg or More Weight Group With Moderate/Severe Chronic Plaque Psoriasis

Who this might be right for
Moderate to Severe Chronic Plaque-type Psoriasis
Novartis Pharmaceuticals 331
Post-approval studies (Phase 4)Study completedNCT02752776
What this trial is testing

Evaluate Clear Skin Effect on Quality of Life in Patients With Plaque Psoriasis.

Who this might be right for
Plaque Psoriasis
Novartis Pharmaceuticals 1,660
Large-scale testing (Phase 3)Study completedNCT01241591
What this trial is testing

A Phase 3, Multi Site, Randomized, Double Blind, Placebo Controlled Study Of The Efficacy And Safety Comparing CP- 690,550 And Etanercept In Subjects With Moderate To Severe Chronic Plaque Psoriasis

Who this might be right for
Psoriasis
Pfizer 1,101
Testing effectiveness (Phase 2)Ended earlyNCT03995212
What this trial is testing

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Who this might be right for
Cholestatic Pruritus
Cara Therapeutics, Inc. 14
Early research (Phase 1)Study completedNCT05454462
What this trial is testing

KM-001 Cream for Treatment of Pruritus in Adult Patients With Lichen Simplex Chronicus (LSC)

Who this might be right for
Lichen Simplex Chronicus
Orvida Pharma (formerly Kamari Pharma) 55
Large-scale testing (Phase 3)Study completedNCT03364309
What this trial is testing

Ixekizumab (LY2439821) in Chinese Participants With Moderate-to-Severe Plaque Psoriasis

Who this might be right for
Plaque Psoriasis
Eli Lilly and Company 438
Post-approval studies (Phase 4)Study completedNCT03440736
What this trial is testing

Comparison of Secukinumab 300 mg Combined With a Lifestyle Intervention to Secukinumab Alone for the Treatment of Moderate to Severe Psoriasis Patients With Concomitant Metabolic Syndrome

Who this might be right for
PsoriasisMetabolic Syndrome
Novartis Pharmaceuticals 781
Testing effectiveness (Phase 2)Ended earlyNCT03517566
What this trial is testing

Assess the Safety and Efficacy of ZPL389 in Patients With Moderate to Severe Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
Novartis Pharmaceuticals 293
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06733519
What this trial is testing

TH104 for the Treatment of Pruritus in Primary Biliary Cholangitis

Who this might be right for
PruritusPrimary Biliary Cholangitis
Tharimmune Inc 40
Large-scale testing (Phase 3)Study completedNCT03281538
What this trial is testing

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Who this might be right for
Uremic Pruritus
Cara Therapeutics, Inc. 288
Post-approval studies (Phase 4)WithdrawnNCT03146247
What this trial is testing

Analysis of the Pathogenesis of Itch in Response to Apremilast Therapy in Psoriasis Patients

Who this might be right for
Moderate to Severe Plaque Psoriasis
Diamant Thaci
Large-scale testing (Phase 3)Study completedNCT03998163
What this trial is testing

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Who this might be right for
Uremic Pruritus
Cara Therapeutics, Inc. 222
Testing effectiveness (Phase 2)UnknownNCT06290375
What this trial is testing

HSK21542 in a Peritoneal Dialysis Pruritus Population.

Who this might be right for
Pruritus
Xizang Haisco Pharmaceutical Co., Ltd 250
Testing effectiveness (Phase 2)Study completedNCT03100344
What this trial is testing

Dose-ranging Study of Nemolizumab in Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
Galderma R&D 226
Post-approval studies (Phase 4)Study completedNCT05590585
What this trial is testing

Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial

Who this might be right for
Moderate-to-Severe Atopic DermatitisAtopic Eczema
Regeneron Pharmaceuticals 124
Testing effectiveness (Phase 2)Study completedNCT04256759
What this trial is testing

Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus

Who this might be right for
Pruritus
Mayo Clinic 9
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