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Results for “Moderate-to-severe Ulcerative Colitis”

287 trials

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Showing 20 of 287 results

Not applicableStudy completedNCT05791526
What this trial is testing

An Observational Study to Assess Change in Disease Activity and Adverse Events of Rinvoq in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Japan

Who this might be right for
Ulcerative Colitis
AbbVie 308
Post-approval studies (Phase 4)Looking for participantsNCT07235904
What this trial is testing

Efficacy of Top-down Therapy With Mirikizumab Versus Standard of Care With Azathioprine in Patients With Newly Diagnosed Moderate-to-severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
University Hospital Schleswig-Holstein 300
Not applicableStudy completedNCT02914717
What this trial is testing

The Belgian SMART Study Evaluating the Use of Golimumab for Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Universitaire Ziekenhuizen KU Leuven 100
Not applicableActive Not RecruitingNCT02808780
What this trial is testing

An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Janssen Biotech, Inc. 537
Testing effectiveness (Phase 2)Active Not RecruitingNCT05242484
What this trial is testing

Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 577
Testing effectiveness (Phase 2)Study completedNCT02337608
What this trial is testing

Efficacy and Safety of GLPG1205 in Subjects With Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Galapagos NV 64
Large-scale testing (Phase 3)Ended earlyNCT04985968
What this trial is testing

The Efficacy and Safety of Cobitolimod in Participants With Moderate to Severe Active Left-Sided Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
InDex Pharmaceuticals 171
Large-scale testing (Phase 3)Study completedNCT00853099
What this trial is testing

Adalimumab in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
AbbVie (prior sponsor, Abbott) 274
Large-scale testing (Phase 3)Study completedNCT03945188
What this trial is testing

Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Arena Pharmaceuticals 433
Large-scale testing (Phase 3)Looking for participantsNCT01790061
What this trial is testing

Standardized Fecal Microbiota Transplantation for Ulcerative Colitis

Who this might be right for
BacteriaMicrobiotaFecal Microbiota Transplantation+2 more
The Second Hospital of Nanjing Medical University 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT06636656
What this trial is testing

Test Whether BI 3032950 Helps People With Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Boehringer Ingelheim 45
Testing effectiveness (Phase 2)Looking for participantsNCT06029972
What this trial is testing

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Gilead Sciences 176
Large-scale testing (Phase 3)Active Not RecruitingNCT03596645
What this trial is testing

Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 84
Not applicableStudy completedNCT00791557
What this trial is testing

Open Label Study for Adults With Pyoderma Gangrenosum and Inflammatory Bowel Disease

Who this might be right for
Pyoderma GangrenosumCrohn's DiseaseUlcerative Colitis+1 more
University Hospitals Cleveland Medical Center 2
Testing effectiveness (Phase 2)Ended earlyNCT03298022
What this trial is testing

Efficacy&Safety of ALTB-168 in Patients With Moderate to Severe Active,Anti-TNF Alpha and/or Anti-integrin Refractory UC

Who this might be right for
Ulcerative Colitis
AltruBio Inc. 24
Testing effectiveness (Phase 2)Ended earlyNCT03341962
What this trial is testing

Phase 2 Dose-finding IMU-838 for Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Immunic AG 263
Large-scale testing (Phase 3)UnknownNCT04919252
What this trial is testing

Efficacy and Safety of Vedolizumab in Biologic-naïve Korean Patients With Moderate to Severe Inflammatory Bowel Disease

Who this might be right for
Crohn's Disease and Ulcerative Colitis
Yonsei University 60
Post-approval studies (Phase 4)Study completedNCT06626165
What this trial is testing

Association Between Effectiveness of Mirikizumab and UC Patients With High Neutrophilic Infiltration in Epithelium of the Colonic Mucosa

Who this might be right for
Ulcerative Colitis
Showa Inan General Hospital 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT05611671
What this trial is testing

Evaluate MORF-057 in Adults With Moderately to Severely Active UC

Who this might be right for
Inflammatory Bowel DiseasesColitis, Ulcerative
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) 280
Not applicableStudy completedNCT03532932
What this trial is testing

Evaluate Disease Control and Treatment Pattern in Participants With Moderate to Severe Inflammatory Bowel Disease (IBD) in Real Life Practice

Who this might be right for
Colitis, UlcerativeCrohn DiseaseInflammatory Bowel Diseases
Takeda 1,990
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