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Results for “Moderate-to-severe Ulcerative Colitis”

313 trials

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Showing 20 of 313 results

Large-scale testing (Phase 3)Study completedNCT03398148
What this trial is testing

A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
AbbVie 1,558
Large-scale testing (Phase 3)Looking for participantsNCT07196748
What this trial is testing

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 882
Not applicableWithdrawnNCT02201758
What this trial is testing

Flaxseed Lignan-Enriched Complex (FLC) for the Treatment of Patients With Ulcerative Colitis (UC): A Pilot Assessment

Who this might be right for
Ulcerative Colitis
University of Saskatchewan
Early research (Phase 1)Study completedNCT06693908
What this trial is testing

Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis

Who this might be right for
Moderate to Severe Ulcerative Colitis
Genentech, Inc. 24
Early research (Phase 1)Study completedNCT01831427
What this trial is testing

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of GS-5745 (Andecaliximab) in Adults With Moderate to Severe Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Gilead Sciences 74
Testing effectiveness (Phase 2)Study completedNCT00430898
What this trial is testing

Basiliximab in Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Cerimon Pharmaceuticals 181
Large-scale testing (Phase 3)UnknownNCT05181137
What this trial is testing

Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Reistone Biopharma Company Limited 368
Large-scale testing (Phase 3)Looking for participantsNCT07686081
What this trial is testing

Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
Vanda Pharmaceuticals 150
Testing effectiveness (Phase 2)Ended earlyNCT01716039
What this trial is testing

Pharmacokinetics of Adalimumab With Methotrexate for Treatment of Patients With Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Alimentiv Inc. 22
Large-scale testing (Phase 3)Looking for participantsNCT07185009
What this trial is testing

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Sanofi 751
Post-approval studies (Phase 4)Looking for participantsNCT07235904
What this trial is testing

Efficacy of Top-down Therapy With Mirikizumab Versus Standard of Care With Azathioprine in Patients With Newly Diagnosed Moderate-to-severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
University Hospital Schleswig-Holstein 300
Large-scale testing (Phase 3)Ended earlyNCT02520284
What this trial is testing

Safety and Efficacy of Andecaliximab (GS-5745) in Adults With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Gilead Sciences 165
Large-scale testing (Phase 3)Study completedNCT01465763
What this trial is testing

A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Pfizer 614
Early research (Phase 1)Study completedNCT06281704
What this trial is testing

AK101 in Subjects With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Akeso 34
Testing effectiveness (Phase 2)Study completedNCT02958865
What this trial is testing

Study to Compare Oral PF-06651600, PF-06700841 and Placebo in Subjects With Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Pfizer 319
Post-approval studies (Phase 4)Not Yet RecruitingNCT07665294
What this trial is testing

Combination CurQD and Vedolizumab in Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Ryan C Ungaro 160
Large-scale testing (Phase 3)Study completedNCT02611830
What this trial is testing

Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Takeda 383
Testing effectiveness (Phase 2)Study completedNCT05061446
What this trial is testing

Etrasimod Dose-Ranging Versus Placebo as Induction Therapy Study in Adult Japanese Subjects With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Pfizer 54
Post-approval studies (Phase 4)Study completedNCT05205603
What this trial is testing

Efficacy of Mesalazine Combined With Biologics in the Treatment of Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative ColitisEfficacy, SelfBiologics+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 438
Early research (Phase 1)Not Yet RecruitingNCT07760831
What this trial is testing

A Trial of HRS-7085 Tablets in Patients With Moderate to Severe Active Ulcerative Colitis

Who this might be right for
Moderate to Severe Ulcerative Colitis
Jiangsu HengRui Medicine Co., Ltd. 8
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