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Results for “Moderately to Severely Active Crohn's Disease”

135 trials

Showing 20 of 135 results

Early research (Phase 1)Ended earlyNCT03169894
What this trial is testing

Evaluation of the Safety, Tolerability, and Efficacy of MDGN-002 in Adults With Moderate to Severe Active Crohn's Disease or Ulcerative Colitis

Who this might be right for
Crohn DiseaseUlcerative Colitis
Avalo Therapeutics, Inc. 8
Post-approval studies (Phase 4)WithdrawnNCT02760615
What this trial is testing

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Who this might be right for
Colitis, UlcerativeCrohn Disease
Takeda
Large-scale testing (Phase 3)Study completedNCT02611817
What this trial is testing

Efficacy and Safety of Vedolizumab Subcutaneous (SC) as Maintenance Therapy in Crohn's Disease (CD)

Who this might be right for
Crohn's Disease
Takeda 644
Testing effectiveness (Phase 2)Ended earlyNCT04102111
What this trial is testing

A Study Evaluating Participants With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn Disease
Janssen Research & Development, LLC 48
Large-scale testing (Phase 3)Study completedNCT02914561
What this trial is testing

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn's Disease
Lakefront Biotherapeutics NV 1,372
Post-approval studies (Phase 4)Looking for participantsNCT06581328
What this trial is testing

Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

Who this might be right for
Ulcerative ColitisCrohn's Disease
Takeda 200
Large-scale testing (Phase 3)Study completedNCT03782376
What this trial is testing

Evaluate Efficacy and Safety of Ustekinumab Re-induction Therapy in Participants With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn Disease
Janssen-Cilag Ltd. 215
Testing effectiveness (Phase 2)Study completedNCT02378688
What this trial is testing

Safety and Efficacy of MT-1303 in Subjects With Moderate to Severe Active Crohn's Disease

Who this might be right for
Crohn's Disease
Tanabe Pharma Corporation 78
Large-scale testing (Phase 3)Study completedNCT03234907
What this trial is testing

Vedolizumab Intravenous (IV) Compared to Placebo in Chinese Participants With Crohn's Disease.

Who this might be right for
Crohn's Disease
Takeda 215
Testing effectiveness (Phase 2)Study completedNCT00042055
What this trial is testing

CP-461 for the Treatment of Crohn's Disease

Who this might be right for
Crohn's Disease
Astellas Pharma Inc 30
Large-scale testing (Phase 3)Looking for participantsNCT06100289
What this trial is testing

Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

Who this might be right for
Ulcerative ColitisCrohn's Disease
Takeda 70
Large-scale testing (Phase 3)Looking for participantsNCT06430801
What this trial is testing

Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Who this might be right for
Crohn's Disease
Merck Sharp & Dohme LLC 1,200
Large-scale testing (Phase 3)Study completedNCT00206674
What this trial is testing

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease

Who this might be right for
Crohn Disease
Genzyme, a Sanofi Company 286
Not applicableStudy completedNCT01338740
What this trial is testing

Switching From Adalimumab to Infliximab

Who this might be right for
Crohn's Disease
University Hospital, Ghent 21
Not applicableStudy completedNCT01218360
What this trial is testing

Observational Study of Disease Severity in Participants Diagnosed With Crohn's Disease and Long Term Impact of Treatment Strategies in Participants With Moderate to Severe Crohn's Disease (Protocol P06484)

Who this might be right for
Crohn Disease
Merck Sharp & Dohme LLC 71
Testing effectiveness (Phase 2)WithdrawnNCT02913508
What this trial is testing

Vedolizumab Subcutaneous (SC) Versus Intravenous (IV) in Ulcerative Colitis or Crohn's Disease

Who this might be right for
Ulcerative ColitisCrohn's Disease
Takeda
Large-scale testing (Phase 3)Ended earlyNCT01536418
What this trial is testing

An Active Treatment Study to Induce Clinical Response and/or Remission With GSK1605786A in Subjects With Crohn's Disease

Who this might be right for
Crohn's Disease
GlaxoSmithKline 255
Testing effectiveness (Phase 2)Study completedNCT00102921
What this trial is testing

Safety and Activity Study of an Oral Medication to Treat Moderate to Severe Crohn's Disease

Who this might be right for
Crohn Disease
Amgen 70
Testing effectiveness (Phase 2)Looking for participantsNCT07483099
What this trial is testing

LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

Who this might be right for
Crohn Disease
Eli Lilly and Company 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07677514
What this trial is testing

A Phase II Study of H021 Enteric-coated Tablets for Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn's Disease
Jiangsu Carephar Pharmaceutical Co., Ltd. 156
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