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Results for “Moderately to Severely Active Crohn's Disease”

129 trials

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Showing 20 of 129 results

Large-scale testing (Phase 3)Ended earlyNCT03440372
What this trial is testing

Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn Disease
Celgene 625
Large-scale testing (Phase 3)Active Not RecruitingNCT03466411
What this trial is testing

The Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn's Disease
Janssen Research & Development, LLC 1,409
Testing effectiveness (Phase 2)Looking for participantsNCT06764615
What this trial is testing

A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)

Who this might be right for
Crohn's DiseaseUlcerative Colitis
Takeda 183
Testing effectiveness (Phase 2)Study completedNCT00771667
What this trial is testing

Safety and Effectiveness of Ustekinumab in Patients With Moderate to Severe Active Crohn's Disease Who Have Been Previously Treated With Anti-TNF Therapy

Who this might be right for
Crohn's Disease
Centocor, Inc. 526
Large-scale testing (Phase 3)Looking for participantsNCT07196722
What this trial is testing

Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn Disease
Janssen Research & Development, LLC 1,092
Large-scale testing (Phase 3)Ended earlyNCT00295165
What this trial is testing

Efficacy (Induction of Response/Remission) and Safety Study in Patients With Moderate to Severe Crohn's Disease

Who this might be right for
Crohn Disease
Genzyme, a Sanofi Company 33
Large-scale testing (Phase 3)Active Not RecruitingNCT06063967
What this trial is testing

Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease.

Who this might be right for
Crohn's Disease
AbbVie 289
Large-scale testing (Phase 3)Study completedNCT03357471
What this trial is testing

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease

Who this might be right for
Moderate and Severe Active Rheumatoid ArthritisActive Psoriatic ArthritisActive Ankylosing Spondylitis+1 more
UCB Biopharma S.P.R.L. 70
Testing effectiveness (Phase 2)Study completedNCT00102921
What this trial is testing

Safety and Activity Study of an Oral Medication to Treat Moderate to Severe Crohn's Disease

Who this might be right for
Crohn Disease
Amgen 70
Large-scale testing (Phase 3)Not Yet RecruitingNCT07499232
What this trial is testing

Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn Disease
Janssen Research & Development, LLC 530
Large-scale testing (Phase 3)Study completedNCT03464136
What this trial is testing

Safety and Efficacy of Adalimumab Versus Ustekinumab for One Year

Who this might be right for
Crohn Disease
Janssen Scientific Affairs, LLC 386
Large-scale testing (Phase 3)Looking for participantsNCT07184931
What this trial is testing

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn's Disease
Sanofi 980
Testing effectiveness (Phase 2)Study completedNCT02531113
What this trial is testing

Efficacy and Safety Trial of RPC1063 for Moderate to Severe Crohn's Disease

Who this might be right for
Crohn's Disease
Celgene 69
Testing effectiveness (Phase 2)Study completedNCT00265122
What this trial is testing

The Safety and Efficacy of Ustekinumab (CNTO 1275) in Participants With Crohn's Disease

Who this might be right for
Crohn Disease
Centocor, Inc. 131
Testing effectiveness (Phase 2)Active Not RecruitingNCT05242471
What this trial is testing

Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn's Disease
Janssen Research & Development, LLC 703
Large-scale testing (Phase 3)Study completedNCT01369355
What this trial is testing

Evaluate the Safety and Efficacy of Ustekinumab Maintenance Therapy in Patients With Moderately to Severely Active Crohn's Disease (IM-UNITI)

Who this might be right for
Crohn's DiseaseColitisIBD+1 more
Janssen Research & Development, LLC 1,282
Large-scale testing (Phase 3)Study completedNCT02914561
What this trial is testing

Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

Who this might be right for
Crohn's Disease
Galapagos NV 1,372
Large-scale testing (Phase 3)Study completedNCT00207662
What this trial is testing

A Safety and Efficacy Study of Infliximab (Remicade) in Patients With Moderate to Severe Active Crohn's Disease

Who this might be right for
Crohn Disease
Centocor, Inc. 580
Not applicableStudy completedNCT00524537
What this trial is testing

A Long-Term Registry of Humira® (Adalimumab) in Subjects With Moderately to Severely Active Crohn's Disease (CD)

Who this might be right for
Crohn's Disease
AbbVie (prior sponsor, Abbott) 5,025
Testing effectiveness (Phase 2)Study completedNCT02015793
What this trial is testing

Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Two Treatment Modules in Chinese Subjects With Moderate to Severe Crohn's Disease

Who this might be right for
Crohn's Disease
AbbVie 30
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