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Results for “Moderately to Severely Active Ulcerative Colitis (UC)”

61 trials

Showing 20 of 61 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07535489
What this trial is testing

Efficacy and Safety of IPG11406 in Moderately to Severely Active Ulcerative Colitis (Phase 2)

Who this might be right for
Moderately to Severely Active Ulcerative Colitis (UC)
Nanjing Immunophage Biotech Co., Ltd 144
Testing effectiveness (Phase 2)Ended earlyNCT01659138
What this trial is testing

Efficacy and Safety of SAR339658 in Patients With Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Sanofi 28
Not applicableLooking for participantsNCT06838845
What this trial is testing

An Observational Study to Evaluate Effectiveness and Safety of Upadacitinib in Chinese Adult Participants With Moderate to Severely Active Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
AbbVie 80
Large-scale testing (Phase 3)Study completedNCT03398148
What this trial is testing

A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
AbbVie 1,558
Testing effectiveness (Phase 2)Ended earlyNCT01716039
What this trial is testing

Pharmacokinetics of Adalimumab With Methotrexate for Treatment of Patients With Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Alimentiv Inc. 22
Large-scale testing (Phase 3)Study completedNCT04779307
What this trial is testing

Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)

Who this might be right for
Colitis, Ulcerative
Takeda 121
Testing effectiveness (Phase 2)Looking for participantsNCT06254950
What this trial is testing

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Takeda 207
Large-scale testing (Phase 3)Study completedNCT02165215
What this trial is testing

The Efficacy and Safety of Etrolizumab Treatment in Maintenance of Disease Remission in Ulcerative Colitis (UC) Participants Who Are Naive to Tumor Necrosis Factor (TNF) Inhibitors

Who this might be right for
Colitis, Ulcerative
Hoffmann-La Roche 359
Testing effectiveness (Phase 2)Active Not RecruitingNCT05731128
What this trial is testing

Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

Who this might be right for
Colitis Ulcerative
Sanofi 68
Testing effectiveness (Phase 2)Study completedNCT04504383
What this trial is testing

PN-943 in Adults With Moderate to Severe Active Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis Chronic ModerateUlcerative Colitis Chronic Severe
Protagonist Therapeutics, Inc. 169
Testing effectiveness (Phase 2)Ended earlyNCT01671956
What this trial is testing

Evaluation of Safety, Efficacy, Pharmacokinetic and Pharmacodynamic of Bertilimumab in Patients With Active Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis, Active ModerateUlcerative Colitis, Active Severe
Alexion Pharmaceuticals, Inc. 32
Testing effectiveness (Phase 2)Looking for participantsNCT07080034
What this trial is testing

Study of the Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of BCD-261 in Subjects With Moderate to Severe Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
Biocad 198
Testing effectiveness (Phase 2)Active Not RecruitingNCT05611671
What this trial is testing

Evaluate MORF-057 in Adults With Moderately to Severely Active UC

Who this might be right for
Inflammatory Bowel DiseasesColitis, Ulcerative
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) 280
Post-approval studies (Phase 4)Looking for participantsNCT06095128
What this trial is testing

Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Takeda 65
Early research (Phase 1)Study completedNCT04254783
What this trial is testing

Evaluate the Effect of Intravenous (IV) Infusions of Risankizumab on Pharmacokinetics of Cytochome P450 Substrates in Adult Participants With Moderately to Severely Active Ulcerative Colitis or Crohn's Disease

Who this might be right for
Ulcerative Colitis (UC)Crohn's Disease
AbbVie 20
Testing effectiveness (Phase 2)Looking for participantsNCT07374471
What this trial is testing

MB-001 in Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
Mage Biologics 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT06290934
What this trial is testing

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Gilead Sciences 228
Testing effectiveness (Phase 2)Study completedNCT04004611
What this trial is testing

Mirikizumab (LY3074828) in Children and Teenagers With Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Eli Lilly and Company 26
Not applicableActive Not RecruitingNCT05494606
What this trial is testing

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice

Who this might be right for
Ulcerative Colitis
AbbVie 785
Large-scale testing (Phase 3)Study completedNCT03653026
What this trial is testing

The Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
AbbVie 522
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