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Results for “Molecular Abnormality”

24 trials

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Showing 20 of 24 results

Not applicableUnknownNCT03620955
What this trial is testing

Risk-stratified Therapy Based on Molecular Cytogenetic Aberration and Treatment Response in AML

Who this might be right for
Risk-directed TherapyCytogenetic AbnormalityMolecular Abnormality+1 more
Nanfang Hospital, Southern Medical University 1,000
Not applicableEnded earlyNCT00763191
What this trial is testing

Analysis of Oculo-motor Deficiencies Associated With FMR1 Gene Expression (Genetic Abnormality Predisposing to a Neurodegenerative Disease)

Who this might be right for
Pre-mutation on FMR1 Gene
Nantes University Hospital 27
Not applicableLooking for participantsNCT06782451
What this trial is testing

Development of Preclinical Models Derived From Tumors With a Molecular Abnormality of Interest to Test Their Sensitivity to New Anti-tumor Therapies.

Who this might be right for
Neoplasm Malignant
Centre Antoine Lacassagne 50
Large-scale testing (Phase 3)Looking for participantsNCT07218380
What this trial is testing

Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

Who this might be right for
Carcinoma, Transitional CellUrinary Bladder NeoplasmsNeoplasm Metastasis
Eli Lilly and Company 450
Not applicableStudy completedNCT05079074
What this trial is testing

Clinical Application of Circulating Tumor DNA (ctDNA) in Patients With Late-stage Breast Cancer

Who this might be right for
Metastatic Breast CancerCirculating Tumor DNAGene Abnormality
Hunan Cancer Hospital 223
Testing effectiveness (Phase 2)Looking for participantsNCT06239272
What this trial is testing

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Who this might be right for
Adipocytic NeoplasmLiposarcomaAtypical Fibroxanthoma+6 more
St. Jude Children's Research Hospital 139
Not applicableLooking for participantsNCT04151342
What this trial is testing

CAnadian CAncers With Rare Molecular Alterations (CARMA) - Basket Real-world Observational Study (BROS)

Who this might be right for
CancerMalignancies MultipleMalignant Solid Tumor+7 more
University Health Network, Toronto 5,500
Not applicableUnknownNCT02591966
What this trial is testing

Genetic Alteration After Systemic Treatment in Breast Cancer

Who this might be right for
Breast Cancer
Samsung Medical Center 350
Not applicableStudy completedNCT05456048
What this trial is testing

Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML

Who this might be right for
Relapsed Acute Myeloid LeukemiaRefractory Acute Myeloid LeukemiaGene Abnormality+1 more
Nanfang Hospital, Southern Medical University 231
Not applicableLooking for participantsNCT07370792
What this trial is testing

Contribution of Optical Genome Mapping (OGM) in the Diagnosis of Multiple Congenital Malformations With or Without Intellectual Disability Without Genetic Abnormality

Who this might be right for
Congenital Malformations
Céline PEBREL-RICHARD 55
Testing effectiveness (Phase 2)Ended earlyNCT02150967
What this trial is testing

A Phase II, Single Arm Study of BGJ398 in Patients With Advanced Cholangiocarcinoma

Who this might be right for
Advanced CholangiocarcinomaFGFR2 Gene Mutation
QED Therapeutics, a BridgeBio company 143
Testing effectiveness (Phase 2)Temporarily pausedNCT04668365
What this trial is testing

Zanubrutinib Combined With Standard Chemotherapy in the Treatment for Patients With Diffuse Large B Cell Lymphoma

Who this might be right for
Diffuse Large B Cell LymphomaCD79A Gene MutationCD79B Gene Mutation
Henan Cancer Hospital 59
Not applicableStudy completedNCT00001609
What this trial is testing

Studies of Families With Hereditary Cataracts

Who this might be right for
CataractCongenital Anomaly
National Eye Institute (NEI) 1,200
Not applicableStudy completedNCT02437617
What this trial is testing

Genomic Profiling Assay in Phase I

Who this might be right for
Advanced Cancers
M.D. Anderson Cancer Center 500
Not applicableStudy completedNCT05848050
What this trial is testing

Evaluation of the Humoral and Tumoral Molecular Alteration Profile of Brain Metastases

Who this might be right for
Brain Metastases
GCS Ramsay Santé pour l'Enseignement et la Recherche 21
Not applicableStudy completedNCT01198743
What this trial is testing

Presence of Circulating Tumor DNA in Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Assistance Publique - Hôpitaux de Paris 261
Not applicableUnknownNCT04823741
What this trial is testing

Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma

Who this might be right for
Mesothelioma, MalignantGene AbnormalityPleural Mesothelioma
Hospices Civils de Lyon 30
Large-scale testing (Phase 3)UnknownNCT03230162
What this trial is testing

Sildenafil Versus Low Molecular Weight Heparin in Fetal Growth Restriction Treatment

Who this might be right for
Fetal Growth AbnormalityFetal Growth Restriction
Ain Shams University 100
Not applicableUnknownNCT02072551
What this trial is testing

Future of Beta Cells in Adults With Genetic Abnormality Behind Neonatal Diabetes

Who this might be right for
Diabetes
Assistance Publique - Hôpitaux de Paris 17
Not applicableStudy completedNCT02546453
What this trial is testing

Use of Specific Genetic Alteration s of Tumoral Cells Identified by the Next Generation Sequencing Techniques (NGS) to Follow Peripheral Samples of Children With Metastatic and/or High Risk Solid Tumor - NGSKids

Who this might be right for
Metastatic and/or High Risk Solid Tumor of Children
Institut Curie 30
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