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Results for “Molecular Mechanism of Pharmacological Action”

141 trials

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Showing 20 of 141 results

Testing effectiveness (Phase 2)Study completedNCT03340493
What this trial is testing

Determining the Optimal Dose of Tenecteplase Before Endovascular Therapy for Ischaemic Stroke (EXTEND-IA TNK Part 2)

Who this might be right for
Ischemic Stroke
Neuroscience Trials Australia 300
Early research (Phase 1)Study completedNCT02185794
What this trial is testing

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Voxilaprevir in Adults With Chronic Hepatitis C Virus Infection

Who this might be right for
Hepatitis C Virus Infection
Gilead Sciences 101
Large-scale testing (Phase 3)UnknownNCT01204801
What this trial is testing

Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors

Who this might be right for
Breast Cancer
Medifocus, Inc. 238
Not applicableStudy completedNCT05542381
What this trial is testing

The Role of Loteprednol in Reducing Post-Intravitreal Injection Related Pain

Who this might be right for
Age-Related Macular Degeneration
Virginia Polytechnic Institute and State University 64
Early research (Phase 1)Study completedNCT04922593
What this trial is testing

Relative Bioavailability of LY03010 Compared to Listed Drug

Who this might be right for
SchizophreniaPsychotic DisordersMood Disorders+9 more
Luye Pharma Group Ltd. 281
Post-approval studies (Phase 4)Study completedNCT01828385
What this trial is testing

Effect of Magnesium on the Recovery Time of Neuromuscular Blockade With Sugammadex

Who this might be right for
Neuromuscular Blockade
Universidade Federal do Rio de Janeiro 80
Very early researchEnded earlyNCT01694381
What this trial is testing

Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor

Who this might be right for
Acute Ischemic Stroke
TSI, LLC 8
Large-scale testing (Phase 3)Study completedNCT01701401
What this trial is testing

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV

Who this might be right for
Chronic Hepatitis C Virus
Gilead Sciences 870
Testing effectiveness (Phase 2)Study completedNCT00593151
What this trial is testing

Study of Safety, Tolerability, and Anti-Viral Effect of Locteron Compared to PEG-Intron in Patients With Chronic Hepatitis C

Who this might be right for
Hepatitis C
Biolex Therapeutics, Inc. 32
Large-scale testing (Phase 3)Looking for participantsNCT07555483
What this trial is testing

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC 40
Early research (Phase 1)Active Not RecruitingNCT04572451
What this trial is testing

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

Who this might be right for
MelanomaUnresectable Solid TumorsNeoplasms+7 more
Yana Najjar 50
Testing effectiveness (Phase 2)Ended earlyNCT01555489
What this trial is testing

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

Who this might be right for
Stage IV Pancreatic Cancer
Thomas Jefferson University 11
Large-scale testing (Phase 3)UnknownNCT03889626
What this trial is testing

The Maintenance Treatment of Apatinib/Capecitabine Versus Observation in Advanced Gastric Cancer

Who this might be right for
Stomach NeoplasmsGastrointestinal NeoplasmsStomach Diseases+5 more
Fudan University 242
Early research (Phase 1)Study completedNCT04080297
What this trial is testing

Dose Escalation Study in Female Subjects With Breast Cancer Receiving Aromatase Inhibitor or Tamoxifen

Who this might be right for
Vasomotor Symptoms (VMS)
Que Oncology 21
Testing effectiveness (Phase 2)Study completedNCT00050427
What this trial is testing

ET-743 (Trabectedin) in Patients With Advanced Breast Cancer

Who this might be right for
Breast NeoplasmsNeoplasmsNeoplasms by Site+2 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 53
Not applicableApproved For MarketingNCT01779518
What this trial is testing

Expanded Access Program of Sofosbuvir With Ribavirin and With or Without Pegylated Interferon in Aggressive Post-transplant Hepatitis C

Who this might be right for
Post-transplant Hepatitis C
Gilead Sciences
Post-approval studies (Phase 4)UnknownNCT02765594
What this trial is testing

Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy

Who this might be right for
Primary IgA Nephropathy
Peking Union Medical College Hospital 98
Large-scale testing (Phase 3)UnknownNCT04703088
What this trial is testing

ONDANSETRON AND EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAREAN DELIVERY

Who this might be right for
HypotensionAnesthesia; Adverse Effect, Spinal and EpiduralCesarean Section
Laval University 60
Not applicableUnknownNCT04169230
What this trial is testing

Citalopram and Self Emotional Processing

Who this might be right for
Molecular Mechanisms of Pharmacological ActionDepressionDepressive Disorder+3 more
University of Oxford 44
Post-approval studies (Phase 4)Looking for participantsNCT05465031
What this trial is testing

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Who this might be right for
Breast CancerNeoplasm, BreastBreast Diseases+10 more
Silesian Centre for Heart Diseases 600
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