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Results for “Molecular Targeted Therapies”

161 trials

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Showing 20 of 161 results

Not applicableUnknownNCT05609695
What this trial is testing

Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeted Drugs / Locoregional Therapy in the Treatment of Hepatocellular Carcinoma

Who this might be right for
Immune Checkpoint Inhibitor Monotherapy or Combined With Molecular Targeting Drugs / Locoregional Therapy for Hepatocellular Carcinoma
Sun Yat-sen University 100
Not applicableActive Not RecruitingNCT04931329
What this trial is testing

Onco-haematology Vigilance Card

Who this might be right for
Medical OncologyHematologyMolecular Targeted Therapies
University Hospital, Limoges 100
Testing effectiveness (Phase 2)Looking for participantsNCT04116541
What this trial is testing

A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors.

Who this might be right for
Malignant Solid Tumor
Centre Leon Berard 455
Not applicableLooking for participantsNCT02290522
What this trial is testing

Copenhagen Prospective Personalized Oncology (CoPPO)

Who this might be right for
Unspecified Adult Solid Tumor, Protocol Specific
Ulrik Lassen 500
Not applicableStudy completedNCT00897702
What this trial is testing

Molecular Mechanisms of Clinical Resistance to Targeted Therapy Among Patients With Breast Cancer

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 269
Not applicableStudy completedNCT00896766
What this trial is testing

Laboratory Study of Lymphoblasts in Young Patients With High-Risk Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 150
Testing effectiveness (Phase 2)Study completedNCT02645149
What this trial is testing

Molecular Profiling and Matched Targeted Therapy for Patients With Unresectable Advanced or Metastatic Melanoma

Who this might be right for
Melanoma
Melanoma Institute Australia 216
Not applicableLooking for participantsNCT07649629
What this trial is testing

Impact of Liquid Biopsy on the Therapeutic Pathway for Lung Cancer: Advancing the Molecular Characterization of Patients With Advanced Lung Adenocarcinoma by Integrating Liquid Biopsy Into the Early Stages of the Diagnostic and Therapeutic Pathway

Who this might be right for
Advanced Non-small Cell Lung Cancer (NSCLC)
Regina Elena Cancer Institute 70
Not applicableLooking for participantsNCT05667948
What this trial is testing

Molecular Analysis and Treatment Options of Thymic Malignancies

Who this might be right for
Thymic Epithelial TumorThymic CarcinomaThymic Cancer
Shanghai Chest Hospital 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT02465060
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmBladder Carcinoma+49 more
National Cancer Institute (NCI) 6,452
Not applicableUnknownNCT06607120
What this trial is testing

Prognosis Stratification for Advanced HCC Receiving TACE with PD-1/PD-L1 Inhibitors and Molecular Target Therapies

Who this might be right for
Hepatocellular Carcinoma
Zhongda Hospital 950
Not applicableStudy completedNCT02613962
What this trial is testing

Proof -of -Concept Study To Stratify Targeted Therapies Adapted To Molecular Profiling

Who this might be right for
Relapsed or Refractory Pediatric Tumor
Gustave Roussy, Cancer Campus, Grand Paris 791
Large-scale testing (Phase 3)Looking for participantsNCT05722886
What this trial is testing

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Who this might be right for
Haematological MalignancySolid Tumour
Cancer Research UK 825
Not applicableLooking for participantsNCT04274283
What this trial is testing

Tessa Jowell BRAIN MATRIX - Platform Study

Who this might be right for
Glioma
University of Birmingham 1,000
Early research (Phase 1)Study completedNCT04023669
What this trial is testing

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

Who this might be right for
Brain TumorBrain Tumor, RecurrentBrain Tumor, Refractory+10 more
St. Jude Children's Research Hospital 21
Testing effectiveness (Phase 2)Looking for participantsNCT05564377
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Who this might be right for
Advanced Malignant Solid NeoplasmAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+12 more
National Cancer Institute (NCI) 2,900
Large-scale testing (Phase 3)Looking for participantsNCT07440290
What this trial is testing

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+17 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Study completedNCT01728233
What this trial is testing

Dacomitinib (PF-00299804) in Advanced/Metastatic Squamous Cell Carcinoma of the Penis

Who this might be right for
Penile NeoplasmsCarcinoma, Squamous Cell
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 32
Testing effectiveness (Phase 2)Looking for participantsNCT05048901
What this trial is testing

Cabozantinib and Lanreotide as Treatment for Gastroenteropancreatic Neuroendocrine Tumors

Who this might be right for
Neuroendocrine Tumors,Gastroenteropancreatic
National Health Research Institutes, Taiwan 49
Not applicableLooking for participantsNCT06876753
What this trial is testing

Regional Lymph Node Metastasis and Survival Outcomes in Advanced HCC

Who this might be right for
Hepatocellular Carcinoma (HCC)
Zhongda Hospital 300
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