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Results for “Motor Neuron Atrophy”

396 trials

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Showing 20 of 396 results

Not applicableStudy completedNCT06178393
What this trial is testing

Real-World Use of Novel Treatments in Patients With Spinal Muscular Atrophy (SMA): A Multi-Site Retrospective Chart Review of Pediatric SMA Patients Outside of the United States

Who this might be right for
Spinal Muscular Atrophy
Novartis Pharmaceuticals 162
Testing effectiveness (Phase 2)Looking for participantsNCT05747261
What this trial is testing

Study of the Safety and Efficacy of an Adeno-Associated Viral Vector Carrying the SMN Gene After a Single Intravenous Administration of Escalating Doses in Children With Spinal Muscular Atrophy (BLUEBELL)

Who this might be right for
Spinal Muscular Atrophy (SMA)
Biocad 40
Testing effectiveness (Phase 2)Looking for participantsNCT05824169
What this trial is testing

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 1 Patients

Who this might be right for
Spinal Muscular Atrophy
GeneCradle Inc 18
Not applicableEnded earlyNCT03056144
What this trial is testing

Whole Body Vibration Therapy in Children With Spinal Muscular Atrophy

Who this might be right for
Spinal Muscular Atrophy Type 3
The Hong Kong Polytechnic University 1
Not applicableUnknownNCT06320444
What this trial is testing

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Who this might be right for
Motor Neuron Disease, Amyotrophic Lateral SclerosisMotor Neuron Disease Progressive Spinal Muscle AtrophyPrimary Lateral Sclerosis+2 more
University of Dublin, Trinity College 240
Not applicableApproved For MarketingNCT04256265
What this trial is testing

An Expanded Access Program for Risdiplam in Participants With Spinal Muscular Atrophy (SMA)

Who this might be right for
Muscular Atrophy, Spinal
Genentech, Inc.
Not applicableStudy completedNCT05237544
What this trial is testing

Newborn Screening for Spinal Muscular Atrophy (SMA) - a Proof of Principle Study Using Anonymised Blood Spots.

Who this might be right for
Spinal Muscular Atrophy
Great Ormond Street Hospital for Children NHS Foundation Trust 5,065
Testing effectiveness (Phase 2)UnknownNCT06108193
What this trial is testing

Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris

Who this might be right for
Acne Vulgaris
Chang Gung Memorial Hospital 26
Not applicableActive Not RecruitingNCT02327845
What this trial is testing

Phenotype, Genotype & Biomarkers in ALS and Related Disorders

Who this might be right for
Amyotrophic Lateral SclerosisFrontotemporal DementiaPrimary Lateral Sclerosis+3 more
University of Miami 708
Testing effectiveness (Phase 2)Study completedNCT01369901
What this trial is testing

Effect of Functional Exercise in Patients With Spinal Bulbar Muscular Atrophy

Who this might be right for
Motor Neuron Disease
National Institute of Neurological Disorders and Stroke (NINDS) 61
Not applicableLooking for participantsNCT06203106
What this trial is testing

NYSCF Scientific Discovery Biobank

Who this might be right for
ALSAmyotrophic Lateral SclerosisAlzheimer Disease+26 more
New York Stem Cell Foundation Research Institute 10,000
Not applicableUnknownNCT04825119
What this trial is testing

Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusinersen

Who this might be right for
TremorInvoluntary MovementsSMA+1 more
University Medical Centre Ljubljana 110
Not applicableStudy completedNCT03555578
What this trial is testing

Specified Drug-Use Survey of Leuprorelin Acetate Injection Kit 11.25 mg "All-Case Investigation: Spinal and Bulbar Muscular Atrophy (SBMA)"

Who this might be right for
Spinal and Bulbar Muscular Atrophy
Takeda 1,905
Testing effectiveness (Phase 2)Study completedNCT00365599
What this trial is testing

Phase II Trial of SAHA & Tamoxifen for Patients With Breast Cancer

Who this might be right for
Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 43
Not applicableActive Not RecruitingNCT05042921
What this trial is testing

Pediatric Spinal Muscular Atrophy (SMA) China Registry

Who this might be right for
Muscular Atrophy, Spinal
Biogen 600
Large-scale testing (Phase 3)Study completedNCT02594124
What this trial is testing

Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies

Who this might be right for
Spinal Muscular Atrophy
Biogen 292
Not applicableUnknownNCT05761262
What this trial is testing

SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients

Who this might be right for
Spinal Muscular Atrophy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 91
Large-scale testing (Phase 3)Study completedNCT02292537
What this trial is testing

Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA)

Who this might be right for
Spinal Muscular Atrophy
Biogen 126
Not applicableLooking for participantsNCT04010604
What this trial is testing

A Registered Cohort Study on SMA

Who this might be right for
Spinal Muscular Atrophy
Wan-Jin Chen 2,000
Not applicableStudy completedNCT00466349
What this trial is testing

International SMA Patient Registry

Who this might be right for
Muscular Atrophy, Spinal
Indiana University 3,000
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