Early research (Phase 1)Ended earlyNCT06215755What this trial is testingVRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis Verge Genomics 54
Not applicableStudy completedNCT05852405What this trial is testingClinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALSWho this might be right forMotor Neuron Disease, Amyotrophic Lateral Sclerosis Ambulanzpartner Soziotechnologie APST GmbH 2,000
Not applicableLooking for participantsNCT04715399What this trial is testingUPenn Observational Research Repository on Neurodegenerative DiseaseWho this might be right forFrontotemporal Degeneration(FTD)Primary Progressive Aphasia(PPA)Familial Frontotemporal Lobar Degeneration (fFTLD)+6 more University of Pennsylvania 1,000
Not applicableLooking for participantsNCT00317616What this trial is testingThe Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) StudyWho this might be right forAmyotrophic Lateral Sclerosis University of Miami 500
Testing effectiveness (Phase 2)Study completedNCT01083667What this trial is testingSOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)Who this might be right forFamilial Amyotrophic Lateral Sclerosis Weill Medical College of Cornell University 32
Not applicableLooking for participantsNCT05744310What this trial is testingEffects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their FamiliesWho this might be right forAmyotrophic Lateral SclerosisMotor Neuron DiseaseNervous System Diseases+3 more Haukeland University Hospital 200
Large-scale testing (Phase 3)Study completedNCT00706147What this trial is testingPhase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral SclerosisWho this might be right forAmyotrophic Lateral Sclerosis University of Miami 38
Not applicableUnknownNCT05725759What this trial is testingRehabilitation in SOD1 ALS Treated With TofersenWho this might be right forAmyotrophic Lateral SclerosisLou Gehrig DiseaseFamilial Amyotrophic Lateral Sclerosis+2 more Washington University School of Medicine 10
Not applicableStudy completedNCT04293484What this trial is testingCortico-Spinal tDCS as Rehabilitative Intervention in Amyotrophic Lateral SclerosisWho this might be right forMotor Neuron Disease, FamilialAmyotrophic Lateral Sclerosis With Dementia Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 31
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06782724What this trial is testingPsilocybin Therapy for Psychological Distress in Palliative PatientsWho this might be right forCOPD (Chronic Obstructive Pulmonary Disease)ALS (Amyotrophic Lateral Sclerosis)MS (Multiple Sclerosis)+2 more University Medical Center Groningen 108
Not applicableLooking for participantsNCT06539169What this trial is testingFLOWER: Following Longitudinal Outcomes With Epidemiology for Rare DiseasesWho this might be right forAlpha-ThalassemiaBeta-ThalassemiaAmyloidosis+14 more xCures 1,000
Early research (Phase 1)UnknownNCT03981536What this trial is testingEvaluate AP-101 in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis AL-S Pharma 18
Not applicableLooking for participantsNCT03865420What this trial is testingAmyotrophic Lateral Sclerosis (ALS) Families ProjectWho this might be right forALS Columbia University 300
Not applicableUnknownNCT05589987What this trial is testingSpinal Muscular Atrophy on Wheels, Using Power MobilityWho this might be right forSpinal Muscular Atrophy University of Castilla-La Mancha 20
Not applicableWithdrawnNCT01459302What this trial is testingGenetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular DisordersWho this might be right forAmyotrophic Lateral SclerosisFrontotemporal DementiaPLS+7 more University of Massachusetts, Worcester
Very early researchStudy completedNCT03707795What this trial is testingTreatment of FUS-Related ALS With Betamethasone - The TRANSLATE StudyWho this might be right forFamilial Amyotrophic Lateral Sclerosis Edward Kasaraskis 6
Post-approval studies (Phase 4)Looking for participantsNCT05923905What this trial is testingClinical Study to Evaluate the Efficacy and Safety of FB1006 in the Treatment of ALS PatientsWho this might be right forSporadic and Familial Amyotrophic Lateral Sclerosis Peking University Third Hospital 64
Not applicableStudy completedNCT02372773What this trial is testingLongitudinal Evaluation of Familial Frontotemporal Dementia SubjectsWho this might be right forFamilial Frontotemporal Dementia Mayo Clinic 398
Not applicableEnrolling By InvitationNCT03655223What this trial is testingEarly Check: Expanded Screening in NewbornsWho this might be right forSpinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more RTI International 30,000
Not applicableEnded earlyNCT02550691What this trial is testingIdentification of a Biomarker Associated With Cis-duplication of the SMN1 GeneWho this might be right forSpinal Muscular Atrophy University Hospital, Rouen 48