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Results for “Mucopolysaccharidosis II (MPS II)”

96 trials

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Showing 20 of 96 results

Early research (Phase 1)Study completedNCT02262338
What this trial is testing

Safety and Dose Ranging Study of Insulin Receptor MoAb-IDS Fusion Protein in Patients With Hunter Syndrome

Who this might be right for
Mucopolysaccharidosis II
ArmaGen, Inc 6
Not applicableStudy completedNCT03292887
What this trial is testing

Hunter Outcome Survey (HOS)

Who this might be right for
Hunter Syndrome
Shire 1,443
Large-scale testing (Phase 3)Looking for participantsNCT07236606
What this trial is testing

RGX-121-3102 Gene Therapy in Participants With MPS II (Hunter Syndrome)

Who this might be right for
MPS IIHunter Syndrome (MPS II)
REGENXBIO Inc. 2
Not applicableStudy completedNCT01586871
What this trial is testing

Carotid Structure and Function in MPS Syndromes: A Multicenter Study of the Lysosomal Disease Network

Who this might be right for
Mucopolysaccharidoses
University of Minnesota 1,147
Not applicableStudy completedNCT01521429
What this trial is testing

Longitudinal Study of Bone Disease in Children with Mucopolysaccharidoses (MPS) I, II, and VI

Who this might be right for
Mucopolysaccharidoses
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 55
Testing effectiveness (Phase 2)Study completedNCT00146757
What this trial is testing

A Study Evaluating the Safety and Pharmacokinetics of Aldurazyme® (Laronidase) in MPS I Patients Less Than 5 Years Old

Who this might be right for
Mucopolysaccharidosis IHurler SyndromeHurler-Scheie Syndrome+1 more
Genzyme, a Sanofi Company 20
Large-scale testing (Phase 3)Study completedNCT02412787
What this trial is testing

Study of Long Term Safety and Clinical Outcomes of Idursulfase IT and Elaprase Treatment in Pediatric Participants Who Have Completed Study HGT-HIT-094

Who this might be right for
Hunter Syndrome
Shire 56
Not applicableStudy completedNCT04007536
What this trial is testing

Potential Treatment-Responsive Biomarkers and Clinical Outcomes in Hunter Syndrome

Who this might be right for
Mucopolysaccharidosis II
Denali Therapeutics Inc. 18
Large-scale testing (Phase 3)Enrolling By InvitationNCT05594992
What this trial is testing

An Extension Study of JR-141 to Evaluate the Long-term Safety and Efficacy in MPS II (Hunter Syndrome) Subjects

Who this might be right for
Mucopolysaccharidosis II
JCR Pharmaceuticals Co., Ltd. 80
Large-scale testing (Phase 3)Ended earlyNCT00748969
What this trial is testing

Clinical Trial of Growth Hormone in MPS I, II, and VI

Who this might be right for
Mucopolysaccharidosis IMucopolysaccharidosis IIMucopolysaccharidosis VI
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 2
Not applicableLooking for participantsNCT06036693
What this trial is testing

MPS (RaDiCo Cohort) (RaDiCo-MPS)

Who this might be right for
Mucopolysaccharidosis IMucopolysaccharidosis IIMucopolysaccharidosis III+5 more
Institut National de la Santé Et de la Recherche Médicale, France 1,000
Post-approval studies (Phase 4)Study completedNCT00607386
What this trial is testing

Safety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase Therapy

Who this might be right for
Hunter SyndromeMucopolysaccharidosis IIMPS II
Shire 28
Testing effectiveness (Phase 2)Study completedNCT03359213
What this trial is testing

JR-141 in Patients With Mucopolysaccharidosis II (BR21)

Who this might be right for
Mucopolysaccharidosis II
JCR Pharmaceuticals Co., Ltd. 18
Early research (Phase 1)WithdrawnNCT05238324
What this trial is testing

Safety and Efficacy of HMI-203 in ERT-Treated Adults With MPS II

Who this might be right for
Mucopolysaccharidosis II
Homology Medicines, Inc
Large-scale testing (Phase 3)Study completedNCT00069641
What this trial is testing

Iduronate-2-sulfatase Enzyme Replacement Therapy in Mucopolysaccharidosis II (MPS II)

Who this might be right for
Mucopolysaccharidosis II
Shire 96
Not applicableStudy completedNCT06022380
What this trial is testing

Core Outcome Set for Head, Neck and Respiratory Disease in Mucopolysaccharidosis II

Who this might be right for
Mucopolysaccharidosis Type II
Manchester University NHS Foundation Trust 46
Large-scale testing (Phase 3)Enrolling By InvitationNCT06075537
What this trial is testing

An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007

Who this might be right for
Mucopolysaccharidosis II
Denali Therapeutics Inc. 99
Large-scale testing (Phase 3)Looking for participantsNCT02716246
What this trial is testing

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

Who this might be right for
MPS IIIASanfilippo SyndromeSanfilippo A+1 more
Ultragenyx Pharmaceutical Inc 36
Testing effectiveness (Phase 2)Study completedNCT01155778
What this trial is testing

Safety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA Patients

Who this might be right for
Mucopolysaccharidosis (MPS)
Shire 12
Not applicableLooking for participantsNCT05619900
What this trial is testing

Registry of Patients Diagnosed With Lysosomal Storage Diseases

Who this might be right for
Mucopolysaccharidosis IMucopolysaccharidosis IIMucopolysaccharidosis IV A+5 more
University of California, San Francisco 250
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