Not applicableStudy completedNCT02746341What this trial is testingNatural History Study of Patients With MPS IIIAWho this might be right forMucopolysaccharidosis IIIA LYSOGENE 23
Not applicableStudy completedNCT05523206What this trial is testingA Natural History Study of Biomarkers and Clinical Outcomes in Mucopolysaccharidosis Type IIIA (MPS IIIA; Sanfilippo Syndrome)Who this might be right forMucopolysaccharidosis III-A Sanguine Biosciences 15
Not applicableStudy completedNCT01586871What this trial is testingCarotid Structure and Function in MPS Syndromes: A Multicenter Study of the Lysosomal Disease NetworkWho this might be right forMucopolysaccharidoses University of Minnesota 1,147
Early research (Phase 1)Looking for participantsNCT06567769What this trial is testingPhase 1 Study of GC1130A in Patients With Sanfilippo Syndrome Type A (MPS IIIA)Who this might be right forSanfilippo Syndrome Type A GC Biopharma Corp 9
Testing effectiveness (Phase 2)Ended earlyNCT02350816What this trial is testingAn Extension Study to Determine Safety and Efficacy for Pediatric Patients With MPS Type IIIA Disease Who Participated in Study HGT-SAN-093.Who this might be right forSanfilippo SyndromeMucopolysaccharidosis (MPS) Shire 17
Large-scale testing (Phase 3)UnknownNCT03612869What this trial is testingStudy of AAVrh10-h.SGSH Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)Who this might be right forMucopolysaccharidosis Type IIIA LYSOGENE 20
Large-scale testing (Phase 3)Looking for participantsNCT02716246What this trial is testingPhase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSHWho this might be right forMPS IIIASanfilippo SyndromeSanfilippo A+1 more Ultragenyx Pharmaceutical Inc 36
Testing effectiveness (Phase 2)Study completedNCT01155778What this trial is testingSafety, Tolerability, Ascending Dose and Dose Frequency Study of rhHNS Via an IDDD in MPS IIIA PatientsWho this might be right forMucopolysaccharidosis (MPS) Shire 12
Not applicableStudy completedNCT02037880What this trial is testingNatural History Studies of Mucopolysaccharidosis IIIWho this might be right forMucopolysaccharidosis Type IIIAMucopolysaccharidosis Type IIIB Nationwide Children's Hospital 25
Not applicableStudy completedNCT01873911What this trial is testingNeurobehavioral Phenotypes in MPS IIIWho this might be right forSanfilippo Syndrome Type ASanfilippo Syndrome Type BHurler Syndrome University of Minnesota 30
Testing effectiveness (Phase 2)Ended earlyNCT04088734What this trial is testingGene Transfer Study of ABO-102 in Patients With Middle and Advanced Phases of MPS IIIA DiseaseWho this might be right forMPS IIIASanfilippo SyndromeSanfilippo A+1 more Ultragenyx Pharmaceutical Inc 5
Not applicableStudy completedNCT01047306What this trial is testingPatients With Sanfilippo Syndrome Type A (MPS IIIA)Who this might be right forSanfilippo Syndrome Type A Shire 25
Testing effectiveness (Phase 2)Study completedNCT03423186What this trial is testingAssess the Safety and Tolerability of SOBI003 in Pediatric MPS IIIA PatientsWho this might be right forSanfilippo Syndrome Type A (MPS IIIA) Swedish Orphan Biovitrum 6
Testing effectiveness (Phase 2)Ended earlyNCT01299727What this trial is testingExtension of Study HGT-SAN-055 Evaluating Administration of rhHNS in Patients With Sanfilippo Syndrome Type A (MPS IIIA)Who this might be right forSanfilippo Syndrome Shire 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT06095388What this trial is testingPhase I/II Study of JR-441 in Patients With Mucopolysaccharidosis Type IIIAWho this might be right forMucopolysaccharidosis III-A JCR Pharmaceuticals Co., Ltd. 15
Testing effectiveness (Phase 2)Study completedNCT02060526What this trial is testingRandomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA DiseaseWho this might be right forSanfilippo Syndrome Shire 21
Large-scale testing (Phase 3)Enrolling By InvitationNCT04360265What this trial is testingFollow-up Study of AAV-Mediated Gene Transfer (UX111; Previously Known as ABO-102) for MPS Type IIIAWho this might be right forMucopolysaccharidosis IIIAMPS IIIASanfilippo Syndrome+1 more Ultragenyx Pharmaceutical Inc 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT04201405What this trial is testingGene Therapy with Modified Autologous Hematopoietic Stem Cells for Patients with Mucopolysaccharidosis Type IIIAWho this might be right forMucopolysaccharidosis Type IIIA University of Manchester 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT06181136What this trial is testingStudy of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA (Sanfilippo Syndrome Type A)Who this might be right forMucopolysaccharidosis Type IIIA Denali Therapeutics Inc. 20
Testing effectiveness (Phase 2)Study completedNCT03811028What this trial is testingAssess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA PatientsWho this might be right forSanfilippo Syndrome Type A (MPS IIIA) Swedish Orphan Biovitrum 6