Testing effectiveness (Phase 2)Study completedNCT03561870What this trial is testingOlaparib in Recurrent IDH-mutant GliomaWho this might be right forRecurrent IDHMutant High Grade Glioma Hospices Civils de Lyon 35
Not applicableLooking for participantsNCT07832734What this trial is testingMetabolomics and Transcriptomics of Low- and High-Grade GliomasWho this might be right forIDH Wildtype GlioblastomaIDH Mutant Lower-Grade Gliomas I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 220
Early research (Phase 1)Looking for participantsNCT07223034What this trial is testing177Lu-PSMA-617 in People With GliomasWho this might be right forGliomaDiffuse Astrocytoma, IDH-Wildtype (Grade 2-4)Glioblastoma, IDH-wildtype+3 more Memorial Sloan Kettering Cancer Center 20
Early research (Phase 1)Enrolling By InvitationNCT06896110What this trial is testingIntrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade GliomaWho this might be right forGlioblastoma (GBM)Diffuse Midline Glioma (DMG)Astrocytoma, IDH-Mutant, Grade 4+2 more Andrew P. Groves 34
Not applicableStudy completedNCT05375318What this trial is testingBIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological LevelsWho this might be right forAstrocytoma, Grade IVGlioblastomaGlioblastoma Multiforme+5 more Juan M Garcia-Gomez 50
Early research (Phase 1)Looking for participantsNCT06357377What this trial is testingThe Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain TumorsWho this might be right forPediatric Tumor of CNSPediatric Tumor of BrainDiffuse Midline Glioma, H3 K27M-Mutant+5 more Neonc Technologies, Inc. 12
Early research (Phase 1)Ended earlyNCT02031965What this trial is testingOncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By SurgeryWho this might be right forRecurrent Childhood Anaplastic AstrocytomaRecurrent Childhood Anaplastic OligoastrocytomaRecurrent Childhood Anaplastic Oligodendroglioma+4 more Pediatric Brain Tumor Consortium 2
Early research (Phase 1)Active Not RecruitingNCT06632236What this trial is testing5G-EMERALD: Amivantamab in Malignant Brain TumoursWho this might be right forMalignant Primary GliomasGlioblastoma Multiform (Grade IV Astrocytoma)Diffuse Hemispheric Glioma, H3 G34-Mutant+1 more Institute of Cancer Research, United Kingdom 12
Not applicableStudy completedNCT05229198What this trial is testingALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade GliomasWho this might be right forAstrocytoma, Grade IV Juan M Garcia-Gomez 300
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07389278What this trial is testingCombination ADI-PEG 20, TMZ, and RT for Treatment of Newly Diagnosed High-grade Glioma (HGG)Who this might be right forGlioblastomaHigh-Grade Glioma (WHO III-IV)High-grade Glioma+2 more Sabine Mueller, MD, PhD 97
Testing effectiveness (Phase 2)Active Not RecruitingNCT03919071What this trial is testingDabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade GliomaWho this might be right forAnaplastic AstrocytomaAnaplastic Astrocytoma, Not Otherwise SpecifiedAnaplastic Ganglioglioma+5 more National Cancer Institute (NCI) 58
Early research (Phase 1)Looking for participantsNCT06624371What this trial is testingAtovaquone Combined With Radiation in Children With Malignant Brain TumorsWho this might be right forHigh-grade GliomaMedulloblastomaDiffuse Intrinsic Pontine Glioma+1 more Emory University 18
Early research (Phase 1)Study completedNCT01475006What this trial is testingAMG 595 First-in-Human in Recurrent GliomasWho this might be right forAdvanced Malignant GliomaAnaplastic AstrocytomasGlioblastoma Multiforme Amgen 32
Not applicableNo Longer AvailableNCT03134131What this trial is testingExpanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline High Grade GliomasWho this might be right forGlioma Jazz Pharmaceuticals
Early research (Phase 1)Study completedNCT03434262What this trial is testingSJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain TumorsWho this might be right forAnaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Looking for participantsNCT07468136What this trial is testingRetifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade GliomasWho this might be right forAnaplastic OligodendrogliomaAstrocytoma, IDH-Mutant, Grade 3Astrocytoma, IDH-Mutant, Grade 4+3 more Mayo Clinic 33
Early research (Phase 1)Active Not RecruitingNCT05538130What this trial is testingLearn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid TumorsWho this might be right forMelanomaGliomaThyroid Cancer+10 more Pfizer 148
Testing effectiveness (Phase 2)Looking for participantsNCT07301268What this trial is testingGI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 AstrocytomaWho this might be right forGlioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more Mayo Clinic 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT04145115What this trial is testingA Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational BurdenWho this might be right forAstrocytoma, IDH-Mutant, Grade 4Diffuse GliomaGlioblastoma, IDH-Wildtype+1 more National Cancer Institute (NCI) 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT03718767What this trial is testingNivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator PhenotypeWho this might be right forGliomaGlioblastomaHigh Grade Glioma+2 more National Cancer Institute (NCI) 62