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Results for “Mutant High Grade Glioma”

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Showing 20 of 0 results

Early research (Phase 1)Looking for participantsNCT04943848
What this trial is testing

RHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline Glioma, H3 K27M-Mutant
Ann & Robert H Lurie Children's Hospital of Chicago 36
Early research (Phase 1)Active Not RecruitingNCT05835687
What this trial is testing

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Who this might be right for
Central Nervous System NeoplasmsAtypical Teratoid/Rhabdoid TumorDiffuse Midline Glioma, H3 K27M-Mutant+4 more
St. Jude Children's Research Hospital 29
Testing effectiveness (Phase 2)Study completedNCT02684058
What this trial is testing

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+19 more
Novartis Pharmaceuticals 151
Testing effectiveness (Phase 2)Active Not RecruitingNCT05565521
What this trial is testing

UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the Elderly

Who this might be right for
Glioblastoma Multiforme, AdultGlioblastoma, IDH-mutant
Sunnybrook Health Sciences Centre 55
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Very early researchLooking for participantsNCT06636162
What this trial is testing

Window of Opportunity Study of DSP-0390 in Gliomas

Who this might be right for
Glioma, MalignantIDH Mutation
Washington University School of Medicine 20
Testing effectiveness (Phase 2)Study completedNCT03557359
What this trial is testing

Nivolumab for Recurrent or Progressive IDH Mutant Gliomas

Who this might be right for
Gliomas
Fabio Iwamoto, MD 35
Not applicableLooking for participantsNCT06623565
What this trial is testing

Extensive Resection of Malignant Brain Tumors Using Advanced Imaging Techniques

Who this might be right for
GlioblastomaAstrocytoma, IDH-Mutant, Grade 4
Amsterdam UMC, location VUmc 30
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
Testing effectiveness (Phase 2)Active Not RecruitingNCT04201457
What this trial is testing

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Who this might be right for
Low Grade Glioma (LGG) of Brain With BRAF AberrationHigh Grade Glioma (HGG) of the Brain With BRAF AberrationLow Grade Glioma of Brain With Neurofibromatosis Type 1
Pediatric Brain Tumor Consortium 57
Early research (Phase 1)Active Not RecruitingNCT03749187
What this trial is testing

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

Who this might be right for
GlioblastomaIDH1 Gene MutationIDH2 Gene Mutation+7 more
University of California, San Francisco 78
Testing effectiveness (Phase 2)Temporarily pausedNCT03952598
What this trial is testing

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

Who this might be right for
GliomaGliomasHigh Grade Glioma+2 more
National Cancer Institute (NCI) 42
Early research (Phase 1)Ended earlyNCT03296696
What this trial is testing

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Who this might be right for
Glioblastoma or Malignant Glioma
Amgen 30
Testing effectiveness (Phase 2)Ended earlyNCT03295396
What this trial is testing

ONC201 in Adults With Recurrent H3 K27M-mutant Glioma

Who this might be right for
Glioma
Jazz Pharmaceuticals 73
Not applicableLooking for participantsNCT06118723
What this trial is testing

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

Who this might be right for
GlioblastomaHigh-grade GliomaGlioblastoma, IDH-wildtype+9 more
Jasper Gerritsen 784
Early research (Phase 1)Looking for participantsNCT06815029
What this trial is testing

Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 3Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma
City of Hope Medical Center 27
Early research (Phase 1)Looking for participantsNCT06305910
What this trial is testing

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantRecurrent High Grade Glioma
OX2 Therapeutics 24
Testing effectiveness (Phase 2)Looking for participantsNCT06630260
What this trial is testing

5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours

Who this might be right for
Glioblastoma Multiforme (GBM)Glioblastoma Multiform (Grade IV Astrocytoma)Diffuse Hemispheric Glioma, H3 G34-Mutant+1 more
Institute of Cancer Research, United Kingdom 182
Early research (Phase 1)Looking for participantsNCT07544992
What this trial is testing

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma, IDH-Wildtype
City of Hope Medical Center 24
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