Not applicableStudy completedNCT00359515What this trial is testingGenetic Analysis of Oculocerebrorenal Syndrome of LoweWho this might be right forLowe Syndrome National Human Genome Research Institute (NHGRI) 120
Testing effectiveness (Phase 2)Looking for participantsNCT06563999What this trial is testingNeoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations.Who this might be right forLung Cancer Stage IIIMutation Sun Yat-sen University 120
Not applicableUnknownNCT05383014What this trial is testingFLT3-ITD Gene Mutation and CD135 Expression in Acute Myeloid Leukemia.Who this might be right forAcute Myeloid Leukemia Assiut University 82
Not applicableNot Yet RecruitingNCT06393543What this trial is testingInternational Registration of Isolated STIC: to Report and Investigate the Risk of Serous Peritoneal CarcinomatosisWho this might be right forBRCA MutationSerous Tubal Intraepithelial CarcinomaOvarian Carcinoma+1 more Radboud University Medical Center 600
Not applicableLooking for participantsNCT07642908What this trial is testingStriatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD MutationWho this might be right forParkinson Disease University of Michigan 15
Testing effectiveness (Phase 2)UnknownNCT04553887What this trial is testingAlmonertinib as Upfront Treatment for Uncommon EGFR Mutation Harboring Non-Small-Cell Lung Cancer Patients: A Multicenter, Open-Label, Phase II TrialWho this might be right forNon Small Cell Lung Cancer Tianjin Medical University Cancer Institute and Hospital 53
Not applicableStudy completedNCT01352585What this trial is testingExploratory Multi-centre Trial In Patients With ET Treated With XAGRID®Who this might be right forEssential Thrombocythemia (ET) Shire 47
Large-scale testing (Phase 3)UnknownNCT06264778What this trial is testingExploration of Fenestration Decompression Combined With Dalafenib in the Treatment of BRAF Mutant AmeloblastomaWho this might be right forAmeloblastoma Shandong University 10
Not applicableUnknownNCT00977509What this trial is testingGene Mutations in Non-Small Cell Lung Cancer CellsWho this might be right forCarcinoma, Non-Small-Cell Lung National Taiwan University Hospital 200
Post-approval studies (Phase 4)Looking for participantsNCT07142343What this trial is testingTest the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) DiseaseWho this might be right forCHAPLE Disease Regeneron Pharmaceuticals 5
Large-scale testing (Phase 3)Study completedNCT03512314What this trial is testingTherapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency As Open Label ExtensionWho this might be right forXIAP DeficiencyNLRC4-MAS AB2 Bio Ltd. 11
Not applicableUnknownNCT02597335What this trial is testingNon Invasive Detection of IDH1/2 Mutation in GliomasWho this might be right forGliomaIDH1/IDH2 Mutation Assistance Publique - Hôpitaux de Paris 40
Testing effectiveness (Phase 2)Study completedNCT00890825What this trial is testingAZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC PatientsWho this might be right forNon Small Cell Lung Cancer AstraZeneca 88
Large-scale testing (Phase 3)Looking for participantsNCT06881784What this trial is testingStudy of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)Who this might be right forNSCLC (Non-small Cell Lung Cancer)Non-Small Cell Lung CancerNSCLC+2 more Revolution Medicines, Inc. 590
Not applicableStudy completedNCT01990248What this trial is testingAn Observational Safety Study in Zelboraf (Vemurafenib)-Treated Patients With BRAF-V600 Mutation-Positive Unresectable or Metastatic Melanoma (ZeSS)Who this might be right forMalignant Melanoma Hoffmann-La Roche 339
Early research (Phase 1)Looking for participantsNCT06326411What this trial is testingInvestigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid TumorsWho this might be right forOncologyMEK MutationRAF Gene Mutation+6 more Nested Therapeutics, Inc 230
Testing effectiveness (Phase 2)Ended earlyNCT04108858What this trial is testingTesting the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast CancerWho this might be right forAnatomic Stage IV Breast Cancer AJCC v8HER2-Positive Breast CarcinomaMetastatic Breast Carcinoma National Cancer Institute (NCI) 2
Not applicableLooking for participantsNCT06941584What this trial is testingAnalysis of the Role of AIRE in Autoimmune Neurological Diseases Associated With AutoantibodiesWho this might be right forAIRE Deficiency Fondazione Policlinico Universitario Agostino Gemelli IRCCS 40
Large-scale testing (Phase 3)Active Not RecruitingNCT04208178What this trial is testingStudy of Alpelisib (BYL719) in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy in Patients With HER2-positive Advanced Breast Cancer With a PIK3CA MutationWho this might be right forAdvanced HER2+Breast Cancer Novartis Pharmaceuticals 19
Not applicableLooking for participantsNCT01247597What this trial is testingDICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History StudyWho this might be right forPleuropulmonary BlastomaCystic NephromaOvarian Sertoli-Leydig Cell Tumors+2 more National Cancer Institute (NCI) 1,500