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Results for “Mutation Abnormality”

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Showing 20 of 0 results

Early research (Phase 1)Ended earlyNCT02097225
What this trial is testing

Onalespib, Dabrafenib, and Trametinib in Treating Patients With BRAF-Mutant Melanoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Malignant Solid Neoplasm+7 more
National Cancer Institute (NCI) 22
Not applicableAvailableNCT06761976
What this trial is testing

Expanded Access to Provide Sevabertinib (BAY 2927088) for the Treatment of Locally Advanced or Metastatic NSCLC With HER2 Mutation

Who this might be right for
Advanced Non-small Cell Lung CancerCancer
Bayer
Testing effectiveness (Phase 2)Looking for participantsNCT07110246
What this trial is testing

Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

Who this might be right for
BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco 96
Large-scale testing (Phase 3)Ended earlyNCT03447262
What this trial is testing

A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 484
Not applicableUnknownNCT05556369
What this trial is testing

Genetic Characterization of Cardiomyopathies (POLICARDIOMIO2021)

Who this might be right for
Cardiomyopathies
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 288
Testing effectiveness (Phase 2)UnknownNCT04974879
What this trial is testing

Osimertinib Combined With Bevacizumab in the Treatment Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Qingdao Central Hospital 20
Not applicableUnknownNCT03852290
What this trial is testing

C677T and A1298C MTHFR Polymorphisms and Fluoropyrimidine Effectiveness in Metastatic Colon Cancer

Who this might be right for
Colon CancerMTHFR Gene MutationChemotherapeutic Toxicity+1 more
Universidad de Costa Rica 65
Not applicableLooking for participantsNCT07562542
What this trial is testing

Peripheral Blood KIT-D816V Mutation in Adult Systemic Mastocytosis

Who this might be right for
Systemic MastocytosisKIT-D816V Mutation
The First Affiliated Hospital of Soochow University 50
Large-scale testing (Phase 3)Looking for participantsNCT07623200
What this trial is testing

INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

Who this might be right for
Essential Thrombocythemia
Incyte Corporation 426
Not applicableStudy completedNCT03889171
What this trial is testing

Comparison to Psychological, Medical and Emotional Influencing Communication and Achievement Factors to Oncogenetics Tests

Who this might be right for
CancerColorectal CancerBreast Cancer+1 more
University Hospital, Montpellier 200
Testing effectiveness (Phase 2)Study completedNCT03836209
What this trial is testing

Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
PrECOG, LLC. 181
Testing effectiveness (Phase 2)Study completedNCT03117933
What this trial is testing

Olaparib +/- Cediranib or Chemotherapy in Patients With Platinum-resistant Ovarian Cancer

Who this might be right for
Ovarian Cancer
University of Oxford 139
Not applicableStudy completedNCT05404334
What this trial is testing

Of Androgen Receptor Expression in Breast Cancer With or Without BRCA Mutation

Who this might be right for
Breast Cancer
Banaras Hindu University 231
Testing effectiveness (Phase 2)Looking for participantsNCT05470504
What this trial is testing

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

Who this might be right for
Insulin Receptor MutationPartial Lipodystrophy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 25
Early research (Phase 1)UnknownNCT05768321
What this trial is testing

Study of GEC255 in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation

Who this might be right for
Advanced Solid Tumors
GenEros Biopharma Hangzhou Ltd 70
Early research (Phase 1)Active Not RecruitingNCT04141644
What this trial is testing

Safety and Efficacy of Combination Osimertinib and Ipilimumab in Patients w EGFR Mutated NSCLC

Who this might be right for
Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor (Disorder)
University of Utah 24
Not applicableUnknownNCT04216121
What this trial is testing

LAT for Oligoprogressive NSCLC Treated With First-line OSImertinib

Who this might be right for
Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
Universitaire Ziekenhuizen KU Leuven 39
Not applicableLooking for participantsNCT06643000
What this trial is testing

Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal MetastasisEGFR Gene Mutation
Henan Cancer Hospital 60
Large-scale testing (Phase 3)Study completedNCT01807923
What this trial is testing

Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis, Homozygous for the F508del CFTR Mutation
Vertex Pharmaceuticals Incorporated 559
Not applicableLooking for participantsNCT06814431
What this trial is testing

Study on the Incidence of Malignant Neoplasms in Patients With Parkinson's Disease and Heterozygous Mutation of the GBA Gene

Who this might be right for
Idiopathic Parkinson's Disease (PD)
Azienda USL Reggio Emilia - IRCCS 3,000
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