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Results for “Mutation Abnormality”

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Showing 20 of 0 results

Not applicableLooking for participantsNCT00006150
What this trial is testing

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

Who this might be right for
InfectionsPneumoniaImmune System Diseases+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 600
Large-scale testing (Phase 3)UnknownNCT01405079
What this trial is testing

Gefitinib Versus Vinorelbine/Platinum as Adjuvant Treatment in Stage II-IIIA(N1-N2) NSCLC With EGFR Mutation

Who this might be right for
Non-small Cell Lung Cancer
Guangdong Association of Clinical Trials 222
Large-scale testing (Phase 3)Looking for participantsNCT07185997
What this trial is testing

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Who this might be right for
Non-Small-Cell Lung CancerMetastatic Non-Small-Cell Lung CancerAdvanced Non-Small-Cell Lung Cancer+3 more
ArriVent BioPharma, Inc.
Early research (Phase 1)Study completedNCT06056024
What this trial is testing

Test How Well Different Doses of BI 3706674 Are Tolerated by People With Advanced Cancer in the Stomach and Oesophagus

Who this might be right for
Solid Tumor, KRAS Mutation
Boehringer Ingelheim 47
Large-scale testing (Phase 3)Study completedNCT04058353
What this trial is testing

VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 271
Not applicableStudy completedNCT00721864
What this trial is testing

The Molecular Biology of Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Hemoglobinuria, Paroxysmal
University of Utah 10
Not applicableUnknownNCT03859531
What this trial is testing

Gastrointestinal Study at Orkambi Therapy in CF Patients

Who this might be right for
Cystic Fibrosis
Karolinska University Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06363734
What this trial is testing

Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial

Who this might be right for
Non-small Cell Lung CancerEGFR Activating MutationCell Cycle Deregulation+1 more
Tianjin Medical University Cancer Institute and Hospital 32
Testing effectiveness (Phase 2)Study completedNCT03796637
What this trial is testing

Assess Dystrophin Levels in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD) Who Have Been Treated With Ataluren

Who this might be right for
Duchenne Muscular Dystrophy
PTC Therapeutics 6
Not applicableUnknownNCT04921553
What this trial is testing

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)

Who this might be right for
CancerCancer MetastaticNTRK Gene Fusion Overexpression+13 more
Centre Leon Berard 500
Early research (Phase 1)Not Yet RecruitingNCT07650357
What this trial is testing

CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)

Who this might be right for
Advanced Solid TumorNon Small Cell Lung CancerPancreatic Carcinoma+1 more
Clasp Therapeutics, Inc. 140
Testing effectiveness (Phase 2)Study completedNCT02537600
What this trial is testing

Vemurafenib and Cobimetinib Combination in BRAF Mutated Melanoma With Brain Metastasis

Who this might be right for
Malignant Melanoma
Center Eugene Marquis 43
Not applicableEnded earlyNCT00763191
What this trial is testing

Analysis of Oculo-motor Deficiencies Associated With FMR1 Gene Expression (Genetic Abnormality Predisposing to a Neurodegenerative Disease)

Who this might be right for
Pre-mutation on FMR1 Gene
Nantes University Hospital 27
Not applicableNot Yet RecruitingNCT06520189
What this trial is testing

Value of F-18 FDG PET/CT for the Prediction of EGFR Mutation in Lung Cancer Patients

Who this might be right for
Lung Cancer
Assiut University 60
Testing effectiveness (Phase 2)Study completedNCT04300790
What this trial is testing

Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients

Who this might be right for
Breast Cancer
MedSIR 69
Large-scale testing (Phase 3)Not Yet RecruitingNCT07822542
What this trial is testing

A Study Evaluating HS-10370 Plus Platinum-based Doublet Chemotherapy With or Without Adebrelimab vs. Tislelizumab Plus Chemotherapy as First-Line Therapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Jiangsu Hansoh Pharmaceutical Co., Ltd. 448
Testing effectiveness (Phase 2)Looking for participantsNCT06445062
What this trial is testing

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Who this might be right for
Colorectal CancerCRCPancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc. 1,130
Large-scale testing (Phase 3)Study completedNCT00909727
What this trial is testing

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 52
Post-approval studies (Phase 4)Ended earlyNCT01147042
What this trial is testing

Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease

Who this might be right for
IFN-Gamma TherapyCGD Gene MutationCGD Response to IFNg+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 2
Not applicableWithdrawnNCT00084370
What this trial is testing

Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who Are Undergoing Prophylactic Oophorectomy

Who this might be right for
brca1 Mutation Carrierbrca2 Mutation CarrierOvarian Cancer
University of Alabama at Birmingham
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