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Results for “Mutation Abnormality”

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Showing 20 of 0 results

Not applicableActive Not RecruitingNCT04499534
What this trial is testing

BRCA1/2 Flu Vaccine

Who this might be right for
BRCA1 MutationBRCA2 Mutation
Abramson Cancer Center at Penn Medicine 50
Testing effectiveness (Phase 2)Looking for participantsNCT06525636
What this trial is testing

A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia

Who this might be right for
X-linked Hypophosphatemia
Kyowa Kirin Co., Ltd. 39
Testing effectiveness (Phase 2)Study completedNCT01506609
What this trial is testing

Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
AbbVie 294
Large-scale testing (Phase 3)Ended earlyNCT01583114
What this trial is testing

PREclinical Mutation CARriers From Families With DIlated Cardiomyopathy and ACE Inhibitors

Who this might be right for
Dilated Cardiomyopathy
Institut National de la Santé Et de la Recherche Médicale, France 6
Not applicableUnknownNCT00652964
What this trial is testing

PHOX2B Mutation-Confirmed Congenital Central Hypoventilation Syndrome in A Chinese Family: Presentations From Newborn to Adulthood

Who this might be right for
Central Alveolar Hypoventilation Syndrome
National Taiwan University Hospital 20
Not applicableActive Not RecruitingNCT06733337
What this trial is testing

Learn About the Safety of TALZENNA in People With Prostate Cancer.

Who this might be right for
Prostate Cancer
Pfizer 1
Post-approval studies (Phase 4)UnknownNCT02404675
What this trial is testing

High Dose Icotinib in Advanced Non-small Cell Lung Cancer With EGFR 21 Exon Mutation

Who this might be right for
NSCLC
Betta Pharmaceuticals Co., Ltd. 240
Very early researchLooking for participantsNCT07656753
What this trial is testing

Safety and Efficacy Study of PUMCH-E111 Injection in Subjects With RLBP1 Related Inherited Retinal Dystrophy

Who this might be right for
Inherited Retinal DystrophyInherited Retinal Disease
Peking Union Medical College Hospital 6
Large-scale testing (Phase 3)Active Not RecruitingNCT05870319
What this trial is testing

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

Who this might be right for
Non-small Cell Lung Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 376
Not applicableStudy completedNCT07379528
What this trial is testing

Mesenchymal Stem Cells in NPM1 Mutated Low Risk Acute Myeloid Leukemia: a Study of the Tumor Microenvironment and Its Contribution to the Outcome

Who this might be right for
Acute Myeloid Leukaemia (AML)
Fondazione IRCCS Policlinico San Matteo di Pavia 70
Early research (Phase 1)Active Not RecruitingNCT06461286
What this trial is testing

SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)

Who this might be right for
OPA1 Gene MutationAutosomal Dominant Optic AtrophyHereditary Optic Atrophies+1 more
PYC Therapeutics 18
Testing effectiveness (Phase 2)Ended earlyNCT04780945
What this trial is testing

Functional Analysis of BRCAness

Who this might be right for
Ovarian Neoplasm EpithelialHomologous Recombination DeficiencyBRCA1 Mutation+1 more
Leiden University Medical Center 27
Testing effectiveness (Phase 2)Active Not RecruitingNCT04278781
What this trial is testing

AG-120 in People With IDH1 Mutant Chondrosarcoma

Who this might be right for
ChondrosarcomaChondrosarcoma, Grade 2Chondrosarcoma, Grade 3+1 more
Memorial Sloan Kettering Cancer Center 6
Testing effectiveness (Phase 2)UnknownNCT03514901
What this trial is testing

To Evaluate the Efficacy Beyond Progression of Vemurafenib+Cobimetinib Associated With Local Treatment Compared to Second-line Treatment in Patients With BRAFV600+ Metastatic Melanoma in Focal Progression With First-line+Vemurafenib+Cobimetinib.

Who this might be right for
Melanoma MetastaticBRAF V600 Mutation
Intergruppo Melanoma Italiano 120
Testing effectiveness (Phase 2)Study completedNCT01116219
What this trial is testing

Bevacizumab, Pemetrexed Disodium, and Cisplatin or Erlotinib Hydrochloride and Bevacizumab in Treating Patients With Stage IV Non-Small Cell Lung Cancer. A Multicenter Phase II Trial Including Biopsy at Progression (BIO-PRO Trial).

Who this might be right for
Lung Cancer
Swiss Cancer Institute 149
Early research (Phase 1)Study completedNCT02481154
What this trial is testing

Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation

Who this might be right for
Glioma
Institut de Recherches Internationales Servier 95
Testing effectiveness (Phase 2)Active Not RecruitingNCT05230459
What this trial is testing

Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)

Who this might be right for
Limb Girdle Muscular DystrophyLimb-Girdle Muscular Dystrophy Type 2LGMD2I+6 more
AskBio Inc 9
Testing effectiveness (Phase 2)Study completedNCT03456726
What this trial is testing

Study of Tazemetostat in Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma With EZH2 Gene Mutation

Who this might be right for
Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Eisai Co., Ltd. 20
Not applicableUnknownNCT02738684
What this trial is testing

Predict Gefitinib' s Efficacy for Lung Cancer by Plasma Free Nucleic Acids EGFR Gene Mutation Test

Who this might be right for
Lung Adenocarcinoma
Southwest Hospital, China 100
Not applicableUnknownNCT04489706
What this trial is testing

Arsenic Trioxide in Recurrent and Metastatic Ovarian Cancer and Endometrial Cancer With P53 Mutation

Who this might be right for
Ovarian CancerEndometrial Cancer
Ruijin Hospital 20
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